Increased burden of mitochondrial DNA deletions and point mutations in early-onset age-related hearing loss in mitochondrial mutator mice

Experimental Gerontology - Tập 125 - Trang 110675 - 2019
Mi-Jung Kim1, Suraiya Haroon2, Guang-Di Chen3, Dalian Ding3, Jonathan Wanagat4, Lijie Liu3, Yanping Zhang5, Karessa White1, Hyo-Jin Park1, Chul Han1, Kevin Boyd1, Isabela Caicedo1, Kaitlyn Evans1, Paul J. Linser6, Masaru Tanokura7, Tomas Prolla8, Richard Salvi3,9, Marc Vermulst2, Shinichi Someya1
1Department of Aging and Geriatric Research, University of Florida, Gainesville, FL, USA
2Center for Mitochondrial and Epigenomic Medicine, University of Pennsylvania, Philadelphia, PA, USA
3Center for Hearing and Deafness, State University of New York at Buffalo, NY, USA
4Department of Medicine, University of California, Los Angeles, CA, USA
5Gene Expression & Genotyping, Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL, USA
6Whitney Laboratory, University of Florida, St Augustine, FL, USA
7Department of Applied Biological Chemistry, University of Tokyo, Yayoi, Tokyo, Japan
8Department of Genetics, University of Wisconsin, Madison, WI, USA
9Department of Audiology and Speech-Language Pathology, Asia University, Taichung, Taiwan, ROC

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Experimental Gerontology

Tập 125

110675

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