Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence

Biomaterials - Tập 176 - Trang 13-23 - 2018
Silvia A. Ferreira1, Peter A. Faull2, Alexis J. Seymour1, Tracy T.L. Yu1, Sandra Loaiza3, Holger W. Auner3, Ambrosius P. Snijders2, Eileen Gentleman1
1Centre for Craniofacial and Regenerative Biology, King’s College London, London SE1 9RT, UK
2Protein Analysis and Proteomics Platform, The Francis Crick Institute, London NW1 1AT, UK
3Cancer Cell Protein Metabolism Group, Department of Medicine, Imperial College London, London W12 0NN, UK

Tài liệu tham khảo

Foyt, 2018, Exploiting advanced hydrogel Technologies to address key challenges in regenerative medicine, Adv. Healthcare Mater., 7, 10.1002/adhm.201700939 Kloxin, 2009, Photodegradable hydrogels for dynamic tuning of physical and chemical properties, Science, 324, 59, 10.1126/science.1169494 Lutolf, 2003, Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics, Proc. Natl. Acad. Sci. U. S. A., 100, 5413, 10.1073/pnas.0737381100 Walters, 2015, Evolving insights in cell-matrix interactions: elucidating how non-soluble properties of the extracellular niche direct stem cell fate, Acta Biomater., 11, 3, 10.1016/j.actbio.2014.09.038 Bian, 2013, Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis, Proc. Natl. Acad. Sci. U. S. A., 110, 10117, 10.1073/pnas.1214100110 Chung, 2009, Influence of three-dimensional hyaluronic acid microenvironments on mesenchymal stem cell chondrogenesis, Tissue Eng. Part A, 15, 243, 10.1089/ten.tea.2008.0067 Lee, 2017, Mechanical confinement regulates cartilage matrix formation by chondrocytes, Nat. Mater., 16, 1243, 10.1038/nmat4993 Huebsch, 2010, Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate, Nat. Mater., 9, 518, 10.1038/nmat2732 Khetan, 2013, Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels, Nat. Mater., 12, 458, 10.1038/nmat3586 Das, 2016, Stress-stiffening-mediated stem-cell commitment switch in soft responsive hydrogels, Nat. Mater., 15, 318, 10.1038/nmat4483 Chaudhuri, 2016, Hydrogels with tunable stress relaxation regulate stem cell fate and activity, Nat. Mater., 15, 326, 10.1038/nmat4489 Ferreira, 2017, Bi-directional interactions between stem cells and their pericellular matrix direct fate in 3D hydrogels, eCM Meeting Rumman, 2015, Concise review: quiescence in adult stem cells: biological significance and relevance to tissue regeneration, Stem Cell., 33, 2903, 10.1002/stem.2056 Madl, 2017, Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling, Nat. Mater., 16, 1233, 10.1038/nmat5020 Li, 2010, Coexistence of quiescent and active adult stem cells in mammals, Science, 327, 542, 10.1126/science.1180794 Cheung, 2013, Molecular regulation of stem cell quiescence, Nat. Rev. Mol. Cell Biol., 14, 329, 10.1038/nrm3591 Shu, 2002, Disulfide cross-linked hyaluronan hydrogels, Biomacromolecules, 3, 1304, 10.1021/bm025603c Turley, 2002, Signaling properties of hyaluronan receptors, J. Biol. Chem., 277, 4589, 10.1074/jbc.R100038200 Rehfeldt, 2012, Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells, Integr. Biol. (Camb)., 4, 422, 10.1039/c2ib00150k Lv, 2014, Concise review: the surface markers and identity of human mesenchymal stem cells, Stem Cell., 32, 1408, 10.1002/stem.1681 Shu, 2006, Synthesis and evaluation of injectable, in situ crosslinkable synthetic extracellular matrices for tissue engineering, J. Biomed. Mater. Res. A, 79, 902, 10.1002/jbm.a.30831 Chandrasekhar, 1943, Stochastic problems in physics and astronomy, Rev. Mod. Phys., 15, 0001, 10.1103/RevModPhys.15.1 Becker, 2006, Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase, J. Cell. Physiol., 209, 883, 10.1002/jcp.20776 McLeod, 2016, High fidelity visualization of cell-to-cell variation and temporal dynamics in nascent extracellular matrix formation, Sci. Rep., 6, 38852, 10.1038/srep38852 Rappsilber, 2003, Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics, Anal. Chem., 75, 663, 10.1021/ac026117i Eliuk, 2016 Bartosh, 2010, Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their anti-inflammatory properties, Proc. Natl. Acad. Sci. U. S. A., 107, 13724, 10.1073/pnas.1008117107 Ho, 2016, Increased survival and function of mesenchymal stem cell spheroids entrapped in instructive alginate hydrogels, Stem Cells Transl. Med., 5, 773, 10.5966/sctm.2015-0211 Oberlender, 1994, Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis, Development, 120, 177, 10.1242/dev.120.1.177 DeLise, 2002, Alterations in the spatiotemporal expression pattern and function of N-cadherin inhibit cellular condensation and chondrogenesis of limb mesenchymal cells in vitro, J. Cell. Biochem., 87, 342, 10.1002/jcb.10308 Rodgers, 2014, mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert), Nature, 510, 393, 10.1038/nature13255 Yu, 2012, miR-125b Is an adhesion-regulated microRNA that protects mesenchymal stem cells from anoikis, Stem Cell., 30, 956, 10.1002/stem.1064 Mendez-Ferrer, 2010, Mesenchymal and haematopoietic stem cells form a unique bone marrow niche, Nature, 466, 829, 10.1038/nature09262 Morikawa, 2009, Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow, J. Exp. Med., 206, 2483, 10.1084/jem.20091046 Jones, 1993, Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression, Cell, 73, 713, 10.1016/0092-8674(93)90251-K Barker, 2008, The intestinal stem cell, Genes Dev., 22, 1856, 10.1101/gad.1674008 Morrison, 2008, Stem cells and niches: mechanisms that promote stem cell maintenance throughout life, Cell, 132, 598, 10.1016/j.cell.2008.01.038 Ahmed, 2016, Extracellular matrix regulation of stem cell behavior, Curr. Stem Cell Rep., 2, 197, 10.1007/s40778-016-0056-2 Billing, 2016, Comprehensive transcriptomic and proteomic characterization of human mesenchymal stem cells reveals source specific cellular markers, Sci. Rep., 6, 21507, 10.1038/srep21507 Gadde, 2004, Mechanisms and molecules of the mitotic spindle, Curr. Biol., 14, R797, 10.1016/j.cub.2004.09.021 Winer, 2009, Bone marrow-derived human mesenchymal stem cells become quiescent on soft substrates but remain responsive to chemical or mechanical stimuli, Tissue Eng. Part A, 15, 147, 10.1089/ten.tea.2007.0388 Chiquet-Ehrismann, 2014, Tenascins in stem cell niches, Matrix Biol. : J. Int. Soc. Matrix Biol., 37, 112, 10.1016/j.matbio.2014.01.007 Gattazzo, 2014, Extracellular matrix: a dynamic microenvironment for stem cell niche, Biochim. Biophys. Acta, 1840, 2506, 10.1016/j.bbagen.2014.01.010 Yamaguchi, 1990, Negative regulation of transforming growth factor-beta by the proteoglycan decorin, Nature, 346, 281, 10.1038/346281a0 Bi, 2005, Extracellular matrix proteoglycans control the fate of bone marrow stromal cells, J. Biol. Chem., 280, 30481, 10.1074/jbc.M500573200 Chen, 2007, Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts, J. Bone Miner. Res. : Off. J. Am. Soc. Bone Min. Res., 22, 1943, 10.1359/jbmr.070725 Annes, 2003, Making sense of latent TGF-beta activation, J. Cell Sci., 116, 217, 10.1242/jcs.00229 Qazi, 2017, Biomaterials that promote cell-cell interactions enhance the paracrine function of MSCs, Biomaterials, 140, 103, 10.1016/j.biomaterials.2017.06.019 Davis, 2008, Membrane nanotubes: dynamic long-distance connections between animal cells, Nat. Rev. Mol. Cell Biol., 9, 431, 10.1038/nrm2399 Andaloussi, 2013, Extracellular vesicles: biology and emerging therapeutic opportunities, Nat. Rev. Drug Discov., 12, 347, 10.1038/nrd3978 Mauck, 2006, Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture, Osteoarthritis Cartilage, 14, 179, 10.1016/j.joca.2005.09.002 Fuchs, 2009, The tortoise and the hair: slow-cycling cells in the stem cell race, Cell, 137, 811, 10.1016/j.cell.2009.05.002 Quarta, 2016, An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy, Nat. Biotechnol., 34, 752, 10.1038/nbt.3576