IL-8 negatively regulates ABCA1 expression and cholesterol efflux via upregulating miR-183 in THP-1 macrophage-derived foam cells

Cytokine - Tập 122 - Trang 154385 - 2019
Xiao-Er Tang1, Heng Li2, Ling-Yan Chen3, Xiao-Dan Xia3, Zhen-Wang Zhao3, Xi-Long Zheng4, Guo-Jun Zhao5, Chao-Ke Tang3
1Department of Pathophysiology, Shaoyang University, Shaoyang, Hunan 422000, China
2The Clinic Medical College, Guilin Medical University, No. 1 Zhiyuan Road, Guilin, Guangxi 541100, China
3Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medicine Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan 421001, China
4Department of Biochemistry and Molecular Biology, The Libin Cardiovascular Institute of Alberta, The University of Calgary, Health Sciences Center, 3330 Hospital Dr. N.W., Calgary, Alberta T2N 4N1, Canada
5Department of Histology and Embryology, Guilin Medical University, Guilin, Guangxi 541004, China

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