Aggresomes, inclusion bodies and protein aggregation

London, 1974, Renaturation of Escherichia coli tryptophanase after exposure to 8 m urea. Evidence for the existence of nucleation centers, Eur. J. Biochem., 47, 409, 10.1111/j.1432-1033.1974.tb03707.x Wetzel, 1994, Mutations and off-pathway aggregation of proteins, Trends Biotechnol., 12, 193, 10.1016/0167-7799(94)90082-5 Haase-Pettingell, 1988, Formation of aggregates from a thermolabile in vivo folding intermediate in P22 tailspike maturation. A model for inclusion body formation, J. Biol. Chem., 263, 4977, 10.1016/S0021-9258(18)68883-0 Fink, 1998, Protein aggregation: folding aggregates, inclusion bodies and amyloid, Fold. Design, 3, R9, 10.1016/S1359-0278(98)00002-9 Ellgaard, 1999, Setting the standards: quality control in the secretory pathway, Science, 286, 1882, 10.1126/science.286.5446.1882 Wickner, 1999, Posttranslational quality control: folding, refolding, and degrading proteins, Science, 286, 1888, 10.1126/science.286.5446.1888 Tran, 1999, Aggregates in neurodegenerative disease: crowds and power?, Trends Neurosci., 22, 194, 10.1016/S0166-2236(99)01409-5 Serio, 2000, Protein-only inheritance in yeast: something to get [PSI+]-ched about, Trends Cell Biol., 10, 98, 10.1016/S0962-8924(99)01711-0 Agashe, 2000, Roles of molecular chaperones in cytoplasmic protein folding, Semin. Cell Dev. Biol., 11, 15, 10.1006/scdb.1999.0347 Hammond, 1995, Quality control in the secretory pathway, Curr. Opin. Cell Biol., 7, 523, 10.1016/0955-0674(95)80009-3 Kopito, 1997, ER quality control: the cytoplasmic connection, Cell, 88, 427, 10.1016/S0092-8674(00)81881-4 Ward, 1995, Degradation of CFTR by the ubiquitin–proteasome pathway, Cell, 83, 121, 10.1016/0092-8674(95)90240-6 Fayadat, 1998, Human thyroperoxidase is largely retained and rapidly degraded in the endoplasmic reticulum. Its N-glycans are required for folding and intracellular trafficking, Endocrinology, 139, 4277, 10.1210/en.139.10.4277 Ward, 1994, Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins, J. Biol. Chem., 269, 25710, 10.1016/S0021-9258(18)47306-1 Petaja-Repo, 2000, Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor, J. Biol. Chem., 275, 13727, 10.1074/jbc.275.18.13727 Couve, 1998, Intracellular retention of recombinant GABAB receptors, J. Biol. Chem., 273, 26361, 10.1074/jbc.273.41.26361 Chen, 1988, Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment, J. Cell Biol., 107, 2149, 10.1083/jcb.107.6.2149 Schubert, 2000, Rapid degradation of a large fraction of newly synthesized proteins by proteasomes, Nature, 404, 770, 10.1038/35004754 Zhou, 1999, The engagement of Sec61p in the ER dislocation process, Mol. Cell, 4, 925, 10.1016/S1097-2765(00)80222-1 Voges, 1999, The 26S proteasome: a molecular machine designed for controlled proteolysis, Annu. Rev. Biochem., 68, 1015, 10.1146/annurev.biochem.68.1.1015 Johnston, 1995, Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway, J. Biol. Chem., 270, 8172, 10.1074/jbc.270.14.8172 Thrower, 2000, Recognition of the polyubiquitin proteolytic signal, EMBO J., 19, 94, 10.1093/emboj/19.1.94 Zettlmeissl, 1979, Reconstitution of lactic dehydrogenase. Noncovalent aggregation vs. reactivation. 1. Physical properties and kinetics of aggregation, Biochemistry, 18, 5567, 10.1021/bi00592a007 Speed, 1996, Specific aggregation of partially folded polypeptide chains: the molecular basis of inclusion body composition, Nat. Biotechnol., 14, 1283, 10.1038/nbt1096-1283 Lansbury, 1997, Structural neurology: are seeds at the root of neuronal degeneration?, Neuron, 19, 1151, 10.1016/S0896-6273(00)80406-7 Garcı́a-Mata, 1999, Characterization and dynamics of aggresome formation by a cytosolic GFP chimera, J. Cell Biol., 146, 1239, 10.1083/jcb.146.6.1239 Johnston, 1998, Aggresomes: a cellular response to misfolded proteins, J. Cell Biol., 143, 1883, 10.1083/jcb.143.7.1883 Wigley, 1999, Dynamic association of proteasomal machinery with the centrosome, J. Cell Biol., 145, 481, 10.1083/jcb.145.3.481 Notterpek, 1999, PMP22 accumulation in aggresomes: implications for CMT1A pathology, Neurobiol. Dis., 6, 450, 10.1006/nbdi.1999.0274 Johnston, 2000, Formation of high molecular weight complexes of mutant Cu, Zn superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis, Proc. Natl. Acad. Sci. U. S. A., 97, 12571, 10.1073/pnas.220417997 Lippincott-Schwartz, 1998, Cytoskeletal proteins and Golgi dynamics, Curr. Opin. Cell Biol., 10, 52, 10.1016/S0955-0674(98)80086-0 Wójcik, 1996, Ubiquitin-mediated proteolysis centers in HeLa cells: indication from studies of an inhibitor of the chymotrypsin-like activity of the proteasome, Eur. J. Cell Biol., 71, 311 Wójcik, 1997, An inhibitor of the chymotrypsin-like activity of the proteasome (PSI) induces similar morphological changes in various cell lines, Folia Histochem. Cytobiol., 35, 211 Fabunmi, 2000, Activity and regulation of the centrosome-associated proteasome, J. Biol. Chem., 275, 409, 10.1074/jbc.275.1.409 Antón, 1999, Intracellular localization of proteasomal degradation of a viral antigen, J. Cell Biol., 146, 113, 10.1083/jcb.146.1.113 Herrmann, 2000, Intermediate filaments and their associates: multi-talented structural elements specifying cytoarchitecture and cytodynamics, Curr. Opin. Cell Biol., 12, 79, 10.1016/S0955-0674(99)00060-5 Goldman, 1971, The role of three cytoplasmic fibers in BHK-21 cell motility. I. Microtubules and the effects of colchicine, J. Cell Biol., 51, 752, 10.1083/jcb.51.3.752 Laszlo, 1991, The latent membrane protein-1 in Epstein–Barr-virus-transformed lymphoblastoid cells is found with ubiquitin–protein conjugates and heat-shock protein 70 in lysosomes oriented around the microtubule organizing centre, J. Pathol., 164, 203, 10.1002/path.1711640305 Vidair, 1996, Heat shock causes protein aggregation and reduced protein solubility at the centrosome and other cytoplasmic locations, Int. J. Hyperthermia, 12, 681, 10.3109/02656739609027676 Brown, 1994, Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes, J. Cell. Physiol., 160, 47, 10.1002/jcp.1041600107 Wójcik, 1997, On the spatial organization of ubiquitin-dependent proteolysis in HeLa cells, Folia Histochem. Cytobiol., 35, 117 Palmer, 1996, Subpopulations of proteasomes in rat liver nuclei, microsomes and cytosol, Biochem. J., 316, 401, 10.1042/bj3160401 Hershko, 1997, Roles of ubiquitin-mediated proteolysis in cell cycle control, Curr. Opin. Cell Biol., 9, 788, 10.1016/S0955-0674(97)80079-8 Mortimore, 1996, Autophagy, Subcell. Biochem., 27, 93, 10.1007/978-1-4615-5833-0_4 Mayer, 1989, Intermediate filament–ubiquitin diseases: implications for cell sanitization, Biochem. Soc. Symp., 55, 193 Okamoto, 1991, Reexamination of granulovacuolar degeneration, Acta Neuropathol., 82, 340, 10.1007/BF00296544 Teckman, 2000, Retention of mutant a1-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response, Am. J. Physiol., 279, G961 Baas, 1998, The role of motor proteins in establishing the microtubule arrays of axons and dendrites, J. Chem. Neuroanat., 14, 175, 10.1016/S0891-0618(98)00012-X Gonatas, 1998, The involvement of the Golgi apparatus in the pathogenesis of amyotrophic lateral sclerosis, Alzheimer's disease, and ricin intoxication, Histochem. Cell Biol., 109, 591, 10.1007/s004180050257