Clinical profile and predictors of mortality in patients of acute-on-chronic liver failure

Jalan, 2002, Acute-on-chronic liver failure: pathophysiological basis of therapeutic options, Blood Purif, 20, 252, 10.1159/000047017 O’Grady, 1989, Early indicators of prognosis in fulminant hepatic failure, Gastroenterology, 97, 439, 10.1016/0016-5085(89)90081-4 Sarin, 2009, Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL), Hepatol Int, 3, 269, 10.1007/s12072-008-9106-x Jenq, 2007, RIFLE classification can predict short-term prognosis in critically ill cirrhotic patients, Intensive Care Med, 33, 1921, 10.1007/s00134-007-0760-6 Sen, 2004, Pathophysiological effects of albumin dialysis in acute-on-chronic liver failure: a randomized controlled study, Liver Transpl, 10, 1109, 10.1002/lt.20236 Wehler, 2001, Short-term prognosis in critically ill patients with cirrhosis assessed by prognostic scoring systems, Hepatology, 34, 255, 10.1053/jhep.2001.26522 Cholongitas, 2006, Risk factors, sequential organ failure assessment and model for end-stage liver disease scores for predicting short term mortality in cirrhotic patients admitted to intensive care unit, Aliment Pharmacol Ther, 23, 883, 10.1111/j.1365-2036.2006.02842.x Vincent, 1998, Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on “sepsis-related problems” of the European Society of Intensive Care Medicine, Crit Care Med, 26, 1793, 10.1097/00003246-199811000-00016 Tsai, 2004, Multiple organ system failure in critically ill cirrhotic patients. A comparison of two multiple organ dysfunction/failure scoring systems, Digestion, 69, 190, 10.1159/000078789 Zauner, 2000, Short-term prognosis in critically ill patients with liver cirrhosis: an evaluation of a new scoring system, Eur J Gastroenterol Hepatol, 12, 517, 10.1097/00042737-200012050-00007 Zauner, 1996, Outcome prediction for patients with cirrhosis of the liver in a medical ICU: a comparison of the APACHE scores and liver-specific scoringsystems, Intensive Care Med, 22, 559, 10.1007/BF01708096 Rabe, 2004, Does intubation really equal death in cirrhotic patients? Factors influencing outcome in patients with liver cirrhosis requiring mechanical ventilation, Intensive Care Med, 30, 1564, 10.1007/s00134-004-2346-x Aggarwal, 2001, Predictors of mortality and resource utilization in cirrhotic patients admitted to the medical ICU, Chest, 119, 1489, 10.1378/chest.119.5.1489 Gildea, 2004, Predictors of long-term mortality in patients with cirrhosis of the liver admitted to a medical ICU, Chest, 126, 1598, 10.1378/chest.126.5.1598 Singh, 1998, Outcome of patients with cirrhosis requiring intensive care unit support: prospective assessment of predictors of mortality, J Gastroenterol, 33, 73, 10.1007/s005350050047 Heemann, 2002, Albumin dialysis in cirrhosis with superimposed acute liver injury: a prospective, controlled study, Hepatology, 36, 949, 10.1053/jhep.2002.36130 Sen, 2004, Baseline SOFA score and its lack of early improvement accurately predicts mortality in patients with acute-on-chronic liver failure, Hepatology, 40, 489A Stauber, 2006, Evaluation of four prognostic scores in patients with acute-on-chronic liver failure, J Hepatol, 44, S69, 10.1016/S0168-8278(06)80166-2 Liu, 2009, Analysis of prognostic factors for patients with acute-on-chronic liver failure, Zhonghua Gan Zang Bing Za Zhi, 17, 607 Yu, 2006, Prediction of the prognosis in patients with acute-on-chronic hepatitis using the MELD scoring system, J Gastroenterol Hepatol, 21, 1519, 10.1111/j.1440-1746.2006.04510.x Tsai, 2003, Organ system failure scoring system can predict hospital mortality in critically ill cirrhotic patients, J Clin Gastroenterol, 37, 251, 10.1097/00004836-200309000-00011 Ho, 2004, Outcome prediction for critically ill cirrhotic patients: a comparison of APACHE II and Child–Pugh scoring systems, J Intensive Care Med, 19, 105, 10.1177/0885066603261991 Cholongitas, 2005, MELD is not enough–enough of MELD?, J Hepatol, 42, 475, 10.1016/j.jhep.2005.02.002 Papatheodoridis, 2005, MELD vs Child–Pugh and creatinine-modified Child–Pugh score for predicting survival in patients with decompensated cirrhosis, World J Gastroenterol, 11, 3099, 10.3748/wjg.v11.i20.3099