COX expression and PGE2 and PGD2 production in experimental acute and chronic gastric lesions

International Immunopharmacology - Tập 5 - Trang 369-379 - 2005
Virginia Motilva1, Catalina Alarcón de la Lastra1, Leo Bruseghini2, Juan Manuel Herrerias3, Susana Sánchez-Fidalgo1
1Department of Pharmacology, Faculty of Pharmacy, University of Seville, Spain
2Zambón Group, Barcelona, Spain
3Service of Digestive, “Virgen Macarena” Hospital, University of Seville, Spain

Tài liệu tham khảo

DeMaria, 2003, Coxibs-beyond the GI tract: renal and cardiovascular issues, J. Pain Symptom Manage., 25, S41, 10.1016/S0885-3924(02)00630-9 Halter, 2001, Cyclooxygenase 2, implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives, Gut, 49, 443, 10.1136/gut.49.3.443 Fukushima, 1990, Prostaglandin J2-anti-tumour and anti-viral activities and the mechanisms involved, Eicosanoids, 3, 189 Joh, 2003, The protective effect of rebamipide on paracellular permeability of rat gastric epithelial cells, Aliment. Pharmacol. Ther., 18, 133, 10.1046/j.1365-2036.18.s1.15.x Martel-Pelletier, 2003, Cyclooxygenase-2 and prostaglandins in articular tissues, Semin. Arthritis Rheum., 33, 155, 10.1016/S0049-0172(03)00134-3 Harris, 2002, Prostaglandins as modulators of immunity, Trends Immunol., 23, 144, 10.1016/S1471-4906(01)02154-8 Castrillo, 2000, Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-delta(12,14)-prostaglandin J(2) in activated murine macrophages, Mol. Cell. Biol., 20, 1692, 10.1128/MCB.20.5.1692-1698.2000 Rossi, 2000, Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase, Nature, 403, 103, 10.1038/47520 Nakajima, 2001, Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury, Gastroenterology, 120, 460, 10.1053/gast.2001.21191 Su, 1999, A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response, J. Clin. Invest., 104, 383, 10.1172/JCI7145 Kawahito, 2000, 15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats, J. Clin. Invest., 106, 189, 10.1172/JCI9652 Jimenez, 2002, Mechanisms involved in protection afforded by l-arginine in ibuprofen-induced gastric damage: role of nitric oxide and prostaglandins, Dig. Dis. Sci., 47, 44, 10.1023/A:1013203217788 Sánchez-Fidalgo, 2004, Angiogenesis, cell proliferation and apoptosis in gastric ulcer healing. Effect of a selective COX-2 inhibitor, Eur. J. Pharmacol., 505, 187, 10.1016/j.ejphar.2004.10.019 Motilva, 1996, Role of polymorphonuclear leukocytes and oxygen-derived free radicals in chronic gastric lesion induced by acetic acid in rat, Gen. Pharmacol., 27, 545, 10.1016/0306-3623(95)02025-X Du, 2002, Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine, J. Neurochem., 80, 771, 10.1046/j.0022-3042.2001.00737.x Sawaoka, 1997, Expression of the cyclooxygenase-2 gene in gastric epithelium, J. Clin. Gastroenterol., 25, S105, 10.1097/00004836-199700001-00018 Gretzer, 2001, Effects of specific inhibition of cyclooxygenase 1 and cyclooxygenase 2 in the rat stomach with normal mucosa and after acid challenge, Br. J. Pharmacol., 132, 1565, 10.1038/sj.bjp.0703955 Villegas, 2004, Mucosal damage induced by preferential COX-1 and COX-2 inhibitors: Role of prostaglandins and inflammatory response, Life Sci., 74, 873, 10.1016/j.lfs.2003.07.021 Peskar, 2001, Role of cyclooxygenase-2 in gastric mucosal defense, Life Sci., 69, 2993, 10.1016/S0024-3205(01)01407-2 Perini, 2003, Mucosal repair and COX-2 inhibition, Curr. Pharm. Des., 9, 2207, 10.2174/1381612033454027 Yamamoto, 1999, Inducible types of cyclooxygenase and nitric oxide synthase in adaptive cytoprotection in rat stomachs, J. Physiol. Paris, 93, 405, 10.1016/S0928-4257(99)00128-X Brzozowski, 2000, Expression of cyclooxygenase (COX)-1 and COX-2 in adaptive cytoprotection induced by mild stress, J. Physiol. Paris, 94, 83, 10.1016/S0928-4257(00)00145-5 Reddy, 1999, Genetic evidence for distinct roles of COX-1 and COX-2 in the immediate and delayed phases of prostaglandin synthesis in mast cells, Biochem. Biophys. Res. Commun., 265, 205, 10.1006/bbrc.1999.1658 Mizuno, 1997, Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice, Gastroenterology, 112, 387, 10.1053/gast.1997.v112.pm9024292 Schmassmann, 1998, Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats, Br. J. Pharmacol., 123, 795, 10.1038/sj.bjp.0701672 Brzozowski, 2001, Effect of local application of growth factors on gastric ulcer healing and mucosal expression of cyclooxygenase-1 and -2, Digestion, 64, 15, 10.1159/000048835 Berenguer, 2002, Chronic gastric ulcer healing in rats subjected to selective and non-selective cyclooxygenase-2 inhibitors, Eur. J. Pharmacol., 442, 125, 10.1016/S0014-2999(02)01494-2 Matsumoto, 1999, Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages, Biochem. Biophys. Res. Commun., 230, 110, 10.1006/bbrc.1996.5894 Fournier, 1997, Tumor necrosis factor-alpha inversely regulates prostaglandin D2 and prostaglandin E2 production in murine macrophages. Synergistic action of cyclic AMP on cyclooxygenase-2 expression and prostaglandin E2 synthesis, J. Biol. Chem., 272, 31065, 10.1074/jbc.272.49.31065 Naraba, 1998, Segregated coupling of phospholipases A2, cyclooxygenases, and terminal prostanoid synthases in different phases of prostanoid biosynthesis in rat peritoneal macrophages, J. Immunol., 160, 2974, 10.4049/jimmunol.160.6.2974 Brock, 1999, Arachidonic acid is preferentially metabolizated by cyclooxygenase-2 to prostacyclin and prostaglandin E2, J. Biol. Chem., 274, 11660, 10.1074/jbc.274.17.11660 Dieter, 2000, Functional coupling of cyclooxygenase 1 and 2 to discrete prostanoid synthases in liver macrophages, Biochem. Biophys. Res. Commun., 276, 488, 10.1006/bbrc.2000.3496 Longo, 1998, Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents, Prostaglandins Other Lipid Mediat., 56, 325, 10.1016/S0090-6980(98)00058-6 Watanabe, 1998, Absence of relation between the expression of cyclooxygenase isoforms and the synthesis of prostaglandin E2 in resident and thioglycollate-elicited macrophages in rats, Prostaglandins Other Lipid Mediat., 56, 7, 10.1016/S0090-6980(98)00039-2 Gao, 2003, Formation of prostaglandins E2 and D2 via the isoprostane pathway: mechanism for the generation of bioactive prostaglandins independent cyclooxygenase, J. Biol. Chem., 278, 28479, 10.1074/jbc.M303984200 Gilroy, 1998, Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation, Eur. J. Pharmacol., 355, 211, 10.1016/S0014-2999(98)00508-1 Gilroy, 1999, Inducible cyclooxygenase may have anti-inflammatory properties, Nat. Med., 5, 69, 10.1038/9550 Willoughby, 2001, COX-1, COX-2 and COX-3 and the future treatment of chronic inflammatory disease, Lancet, 355, 646, 10.1016/S0140-6736(99)12031-2 Na, 2003, Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands as bifunctional regulators of cell proliferation, Biochem. Pharmacol., 66, 1381, 10.1016/S0006-2952(03)00488-X Simmons, 1999, Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid anti-inflammatory drugs, Proc. Natl. Acad. Sci. U. S. A., 96, 3275, 10.1073/pnas.96.6.3275