Motherhood alters the cellular response to estrogens in the hippocampus later in life

Allen, 2006, Clinical relevance of the neurotrophins and their receptors, Clin. Sci., 110, 175, 10.1042/CS20050161 Barha, 2009, Different forms of oestrogen rapidly upregulate cell proliferation in the dentate gyrus of adult female rats, J. Neuroendol., 21, 155, 10.1111/j.1365-2826.2008.01809.x Barha, 2010, Low doses of 17α-estradiol and 17β-estradiol facilitate, whereas higher doses of estrone and 17α- and 17β-estradiol impair, contextual fear conditioning in adult female rats, Neuropsychopharm., 35, 547, 10.1038/npp.2009.161 Baum, 2005, Sex, hormones, and Alzheimer's disease, J. Gerontol. A Biol. Sci. Med. Sci., 60, 736, 10.1093/gerona/60.6.736 Brewer, 2009, Estradiol reverses a calcium-related biomarker of brain aging in female rats, J. Neurosci., 29, 6058, 10.1523/JNEUROSCI.5253-08.2009 Brown, 2003, Transient expression of doublecortin during adult neurogenesis, J. Comp. Neurol., 467, 1, 10.1002/cne.10874 Cameron, 1993, Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat, Neurosci, 56, 337, 10.1016/0306-4522(93)90335-D Cameron, 2001, Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus, J. Comp. Neurol., 435, 406, 10.1002/cne.1040 Chiba, 2007, Involvement of granulin in estrogen-induced neurogenesis in the adult rat hippocampus, J. Reprod. Dev., 53, 297, 10.1262/jrd.18108 Dayer, 2003, Short-term and long-term survival of new neurons in the rat dentate gyrus, J. Comp. Neurol., 460, 563, 10.1002/cne.10675 Drapeau, 2003, Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis, Proc. Natl. Acad. Sci. U.S.A., 100, 14385, 10.1073/pnas.2334169100 Galea, 2008, Endocrine regulation of cognition and neuroplasticity: our pursuit to unveil the complex interaction between hormones, the brain, and behavior, Can. J. Exp. Psychol., 62, 247, 10.1037/a0014501 Gatewood, 2005, Motherhood mitigates aging-related decrements in learning and memory, Brain Res. Bull., 66, 91, 10.1016/j.brainresbull.2005.03.016 Hogervorst, 2000, The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: a meta-analysis, Neurosci., 101, 485, 10.1016/S0306-4522(00)00410-3 Jessberger, 2007, Epigenetic modulation of seizure-induced neurogenesis and cognitive decline, J. Neurosci., 30, 5967, 10.1523/JNEUROSCI.0110-07.2007 Jakubs, 2006, Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability, Neuron, 52, 1047, 10.1016/j.neuron.2006.11.004 Kinsley, 2008, Motherhood induces and maintains behavioral and neural plasticity across the lifespan in the rat, Arch. Sex Behav., 37, 43, 10.1007/s10508-007-9277-x Kuhn, 1996, Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation, J. Neurosci., 16, 2027, 10.1523/JNEUROSCI.16-06-02027.1996 Macbeth, 2008, Effects of multiparity on recognition memory, monoaminergic neurotransmitters, and brain-derived neurotrophic factor, Horm. Behav., 54, 7, 10.1016/j.yhbeh.2007.08.011 Pawluski, 2009, Effects of steroid hormones on neurogenesis in the hippocampus of the adult female rodent during the estrous cycle, pregnancy, lactation and aging, Front. Neuroendocrinol., 30, 343, 10.1016/j.yfrne.2009.03.007 Plumpe, 2006, Variability of doublecortin-associated dendrite maturation in adult hippocampal neurogenesis is independent of the regulation of precursor cell proliferation, BMC Neurosci., 7, 77, 10.1186/1471-2202-7-77 Ryan, 2008, Hormonal treatment, mild cognitive impairment and Alzheimer's disease, Int. Psychgeriatr., 20, 47, 10.1017/S1041610207006485 Ryan, 2009, Life-time estrogen exposure and cognitive functioning in later life, Psychoneuroendocrinology, 34, 287, 10.1016/j.psyneuen.2008.09.008 Scharfman, 2006, Estrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: complexity of steroid hormone-growth factor interactions in the adult CNS, Front. Neuroendocrinol., 27, 415, 10.1016/j.yfrne.2006.09.004 Shumaker, 2003, Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the women's health initiative memory study: a randomized controlled trial, JAMA, 289, 2651, 10.1001/jama.289.20.2651 Sun, 2004, Programmed cell death of adult-generated hippocampal neurons is mediated by the proapoptotic gene Bax, J. Neurosci., 24, 11205, 10.1523/JNEUROSCI.1436-04.2004 Turnbull, 1999, Sprague-Dawley rats obtained from different vendors exhibit distinct adrenocorticotropic responses to inflammatory stimuli, Neuroendocrinology, 70, 186, 10.1159/000054475 Veiga, 2004, Sex hormones and brain aging, Exp. Gerontol., 39, 1623, 10.1016/j.exger.2004.05.008 Winocur, 2006, Inhibition of neurogenesis interferes with hippocampus-dependent memory function, Hippocampus, 16, 296, 10.1002/hipo.20163