Somatostatin: A peptide with unexpected physiologic activities

The American Journal of Medicine - Tập 81 - Trang 8-13 - 1986
Paul Brazeau1
1Neuroendocrinology Laboratory, NotreDame Hospital, University of Montreal, Montreal, Quebec, Canada

Tài liệu tham khảo

Brazeau, 1985, Somatostatin: a peptide at the origin of many debates, 25, 257 Furness, 1985, 219 Bohlen, 1980, Isolation and amino acid composition of two somatostatin-like peptides from ovine hypothalamus: somatostatin-28 and somatostatin-25, Biochem Biophys Res Commun, 96, 725, 10.1016/0006-291X(80)91415-1 Brazeau, 1984, Evidence for immunoreactive and bioactive somatostatins secreted in the lumen of the gastrointestinal tract: assessment of intraluminal exocrine secretion, 113 Brazeau, 1984, Gut hormones stimulate two forms of somatostatins (somatostatin-14 and somatostatin28) from the gastro-intestinal tract, 9 Brazeau, 1981, High biological activity of the synthetic replicates of hypothalamic somatostatin-28 and somatostatin-25, Regul Pept, 1, 255, 10.1016/0167-0115(81)90048-3 Schlegel, 1977, Inhibition of secretin, pancreozymin and gastrin release and their biological activities by somatostatin, 361 Schlegel, 1977, Inhibition of cholecystokinin-pancreozymin release by somatostatin, Lancet, II, 166, 10.1016/S0140-6736(77)90182-9 Efendic, 1978, Effect of somatostatin on intestinal motility, Acta Radiol [Diagn] [Stockh], 19, 348, 10.1177/028418517801900209 Stadaas, 1978, Somatostatin inhibits gastric motility in response to distention, Scand J Gastroenterol, 13, 145, 10.3109/00365527809181740 Efendic, 1976, Somatostatin, more than a third pancreatic hormone, Rev Invest Clin, 28, 183 Orci, 1976, Somatostatin in the pancreas and the gastrointestinal tract, 73 Berelowitz, 1978, Subcellular localisation of growth hormone release inhibiting hormone in rat hypothalamus, cerebral cortex, striatum and thalamus, J Neurochem, 31, 351, 10.1111/j.1471-4159.1978.tb07851.x Brazeau, 1978, Somatostatin: isolation, characterization, distribution and blood determination, Metabolism, 27, 1133, 10.1016/0026-0495(78)90031-8 Creutzfeldt, 1978, Somatostatin and the stomach: exocrine and endocrine aspects, Metabolism, 27, 1309, 10.1016/0026-0495(78)90064-1 Uvmas-Wallenstein, 1978, Release of somatostatin into the antral lumen of cats, Metabolism, 27, 1233, 10.1016/0026-0495(78)90049-5 Konturek, 1977, Effect of somatostatin analogs on gastric and pancreatic secretion, 155, 519 Konturek, 1978, Somatostatin and gastrointestinal secretion and motility, Adv Exp Med Biol, 106, 227, 10.1007/978-1-4684-7248-6_30 Schusdziarra, 1978, Pancreatic and gastric somatostatin release in response to intragastric and intraduodenal nutrients and HCI in the dog, J Clin Invest, 62, 509, 10.1172/JCI109154 Zysnar, 1979, Properties of somatostatin-like immunoreactive polypeptides in the canine extrahypothalamic brain and stomach, Endocrinology, 105, 1426, 10.1210/endo-105-6-1426 Trent, 1981, Heterogeneity of somatostatin-like peptides in rat brain pancreas and gastrointestinal tract, Endocrinology, 108, 2033, 10.1210/endo-108-6-2033 Efendic, 1980, Somatostatin, 12, 87 Uvnas-Wallensten, 1980, Effect of intraluminal pH on the release of somatostatin and gastrin into antral, bulbar and ileal pouches of conscious dogs, Acta Physiol Scand, 110, 391, 10.1111/j.1748-1716.1980.tb06686.x Patel, 1981, Multiple forms of immunoreactive somatostatin: comparison of distribution in neural and nonneural tissues and portal plasma of the rat, Endocrinology, 109, 1943, 10.1210/endo-109-6-1943 Brazeau, 1973, A hypothalamic polypeptide that inhibits the secretion of pituitary growth hormone, Science, 179, 77, 10.1126/science.179.4068.77 Mortimer, 1974, Effects of growth-hormone release-inhibiting hormone on circulating glucagon, insulin and growth hormone in normal, diabetic, acromegalic and hypopituitary patients, Lancet, I, 697, 10.1016/S0140-6736(74)92903-1 Parker, 1974, Inhibition of the sleep-related peak in physiologic human growth hormone release by somatostatin, J Clin Endocrinol Metab, 38, 496, 10.1210/jcem-38-3-496 Vale, 1975, Somatostatin, Recent Prog Horm Res, 31, 365 Guillemin, 1976, Somatostatin: physiological and clinical significance, Ann Rev Med, 18, 173 Gerich, 1974, Effects of somatostatin on plasma glucose and glucagon levels in human diabetes mellitus, 291, 544 Yen, 1973, Biological effects of somatostatin in normal and acromegalic subjects, Vol 1, 609 Brazeau, 1974, Inhibition of growth hormone secretion in the rat by synthetic somatostatin, Endocrinology, 94, 184, 10.1210/endo-94-1-184 Brazeau, 1974, Trans-hypothalamic effects of drugs of abuse on the secretion of pituitary hormone, 109 Renaud, 1975, Depressant action of TRH, LH-RH and somatostatin on the activity of central neurons, Nature, 255, 233, 10.1038/255233a0 Martin, 1975, Functions of the central nervous system in the regulation of pituitary GH secretion, 217 Martin, 1977, Neuroendocrine organization of growth hormone secretion, Vol 56, 329 Besser, 1974, Growth hormone release inhibiting hormone in acromegaly, Br Med J, 1, 352, 10.1136/bmj.1.5904.352 Alberti, 1973, Inhibition of insulin secretion by somatostatin, Lancet, II, 1299, 10.1016/S0140-6736(73)92873-0 Koerker, 1974, Somatostatin: hypothalamic inhibitor of the endocrine pancreas, Science, 184, 482, 10.1126/science.184.4135.482 Yen, 1974, Effect of somatostatin in patients with acromegaly: suppression of growth hormone, prolactin, insulin and glucose levels, N Engl J Med, 290, 935, 10.1056/NEJM197404252901704 Gerich, 1978, Somatostatin, 62, 375 Hayes, 1975, Inhibition of gastrin release by somatostatin in vitro, Endocrinology, 96, 1374, 10.1210/endo-96-6-1374 Konturek, 1976, Effect of somatostatin on gastric secretion, mucosal blood flow, and serum gastrin, Gastroenterology, 70, 737, 10.1016/S0016-5085(76)80265-X Konturek, 1976, Somatostatin and the gastrointestinal secretions, Scand J Gastroenterol, 11, 1, 10.1080/00365521.1976.12097064 Robberecht, 1975, Effects of somatostatin on pancreatic exocrine function, 67, 315 Boden, 1975, Somatostatin suppresses secretin and pancreatic exocrine secretion, Science, 190, 163, 10.1126/science.1166308 Konturek, 1976, Effect of growth hormone release-inhibiting hormone on hormones stimulating exocrine pancreatic secretion, J Clin Invest, 58, 1, 10.1172/JCI108438 Gomez-Pan, 1976, Actions of growth hormone releasing inhibiting hormone (somatostatin on the renin aldosterone system), J Clin Endocrinol Metab, 43, 240, 10.1210/jcem-43-1-240 Quesada, 1976, Effect of somatostatin on renin secretion in the isolated perifused rat kidney, Rev Esp Fisiol, 32, 107 Rosenthal, 1976, Inhibition of frusemide-induced hypereminaemia by growth hormone release-inhibiting hormone in man, Lancet, I, 772, 10.1016/S0140-6736(76)91611-1 Bloom, 1975, Effects of somatostatin on motiline levels and gastric emptying, Gut, 16, 834 Deftos, 1976, Somatostatin does not suppress plasma parathyroid hormone, J Clin Endocrinol Metab, 43, 205, 10.1210/jcem-43-1-205 Ipp, 1977, Release of immunoreactive somatostatin from the pancreas in response to glucose, amino acids, cholescystokinin and tolbutamide, J Clin Invest, 60, 760, 10.1172/JCI108829 Ipp, 1977, Release of immunoreactive somatostatin from the pancreas in response to glucose, amino acids, cholescystokinin and tolbutamide, J Clin Invest, 60, 1216, 10.1172/JCI108875 Cherrington, 1977, The effect of somatostatin on glucose uptake and production by rat tissues in vitro, Diabetes, 26, 740, 10.2337/diab.26.8.740 Pott, 1977, Somatostatin effect on intestinal absorption, Verh Dtsch Ges Inn Med, 83, 443 Arnold, 1976, Inhibition of gastric acid and gastrin secretion by somatostatin in man, Z Gastroenterol [Verh], 10, 43 Schrumpf, 1976, The effect of somatostatin on gastrin release and secretion, Scand J Gastroenterol, 11, 41 Guillemin, 1976, Somatostatin inhibits the release of acetylcholine induced electrically in the mysenteric plexus, Endocrinology, 99, 1653, 10.1210/endo-99-6-1653 Renaud, 1976, Hypothalamic releasing factors: physiologic evidence for a regulatory action on central neurons and pathways for their distribution in brain, Pharmacol Biochem Behav, 5, 171, 10.1016/0091-3057(76)90348-8 Regek, 1976, Central site of action of somatostatin (SRIF), Neuropharmacology, 15, 499, 10.1016/0028-3908(76)90062-9