Follow-up of skin lesions during the evolution of COVID-19: a case report

Springer Science and Business Media LLC - Tập 313 - Trang 603-606 - 2020
Vanessa Lucilia Silveira de Medeiros1, Lucas Fagundes Teixeira Silva2
1Dermatology Clinic, Tropical Medicine Department of Federal, Clinics Hospital, University of Pernambuco, Recife, Brazil
2Medical Faculty of Recife, Centro de Ciências Médicas, Federal University of Pernambuco, Recife, Brazil

Tóm tắt

The disease caused by the new coronavirus (COVID-19) has many systemic manifestations affecting the upper airways, lungs, gastrointestinal tract and inducing hematological repercussions. With the evolution of the pandemic, skin lesions were observed. However, there is little information about the evolution of the lesions at this moment. The authors report a case of a patient who had more than one exposure to the coronavirus during the evolution of the disease and manifested different types of edematous lesions. The lesions started in the prodromal period and changed their presentation and localization during the evolution of COVID-19. The lesions regressed quickly with the use of corticoid cream and antihistamine. Viral skin lesions are frequent causes of exanthema. However, viral etiology is not always investigated in acute urticarial and atypical erythematous-edematous conditions. The immunological basis of acute urticaria has points in common with COVID-19, justifying the appearance of lesions. Investigation of viral etiology should always be remembered in acute urticarial and edematous conditions.

Tài liệu tham khảo

Wang C, Horby PW, Hayden FG, Gao GF (2020) A novel coronavirus outbreak of global health concern. Lancet 395(10223):470–473 Liu SL, Saif L (2020) Emerging viruses without borders: The Wuhan Coronavirus. Viruses. https://doi.org/10.3390/v12020130 Imbalzano E, Casciaro M, Quartuccio S, Minciullo PL, Cascio A, Calapai G, Gangemi S (2016) Cutaneous manifestations in COVID-19: a first perspective. J Eur Acad Dermatol. 37(1):18–22 Joob B, Wiwanitkit V (2020) COVID-19 can present with a rash and be mistaken for Dengue. J Am Acad Dermatol. https://doi.org/10.1016/j.jaad.2020.03.036 Cardoso CW, Paploski IAD, Kikuti M, Rodrigues MS, Silva MMO, Campos GS, Sardi SI, Kitron U, Reis MG, Ribeiro GS (2015) Outbreak of exanthematous illness associated with Zika, Chikungunya, and Dengue viruses, Salvador, Brazil. Emerg Infect Dis 21(12):2274–2276. https://doi.org/10.3201/eid2112.151167 Drago F, Ciccarese G, Rebora A, Broccolo F, Parodi A (2016) Pityriasis rosea: a comprehensive classification. Dermatology 232(4):431–437. https://doi.org/10.1159/000445375(Epub 2016 Apr 21) Abdelmaksoud A (2019) Aciclovir for treatment of pityriasis lichenoides? Clin Exp Dermatol 44(1):64. https://doi.org/10.1111/ced.13694(Epub 2018 Jun 20) de Carvalho GC, Hirata FYA, Domingues R, Figueiredo CA, Zaniboni MC, Pereira NV, Sotto MN, Aoki V, da Silva Duarte AJ, Sato MN (2018) Up-regulation of HMGB1 and TLR4 in skin lesions of lichen planus. Arch Dermatol Res 310(6):523–528. https://doi.org/10.1007/s00403-018-1837-5(Epub 2018 May 4) Imbalzano E, Casciaro M, Quartuccio S, Minciullo PL, Cascio A, Calapai G, Gangemi S (2016) Association between urticaria and virus infections: a systematic review. Allergy Asthma Proc 37(1):18–22. https://doi.org/10.2500/aap.2016.37.3915 Kasperska-Zajac A (2012) Acute-phase response in chronic urticaria. J Eur Acad Dermatol Venereol 26(6):665–672 Grzanka R, Damasiewicz-Bodzek A, Kasperska-Zajac A (2018) Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria. Allergy Asthma Clin Immunol 14:27. https://doi.org/10.1186/s13223-018-0255-8 Zhang W, Zhao Y, Zhang F, Wang Q, Li T, Liu Z, Wang J, Qin Y, Zhang X, Yan X, Zeng X, Zhang S (2020) The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): the perspectives of clinical immunologists from China. Clin Immunol 214:108393. https://doi.org/10.1016/j.clim.2020.108393 Chuamanochan M, Chiewchanvit S, Tovanabutra N, Rujiwetpongstorn R, Laosakul K, Maurer M (2019) A case of dengue fever presenting with acute urticaria. Asian Pac J Allergy Immunol. https://doi.org/10.12932/AP-150419-0539 Drago F, Merlo G, Cozzani E, Parodi A (2019) Urticaria associated with Epstein-Barr virus reactivation. G Ital Dermatol Venereol 154(6):721–722