The MerR heavy metal receptor mediates positive activation in a topologically novel transcription complex

Anderson, 1987, Structure of the repressor-operator complex of bacteriophage 434, Nature, 326, 846, 10.1038/326846a0

Barrineau, 1984, The DNA sequence of the mercury resistance operon of the Inc FII Plasmid NR1, J. Mol. Appl. Genet., 2, 601

Borowiec, 1986, High resolution analysis of lac transcription complexes inside cells, Biochemistry, 25, 5051, 10.1021/bi00366a012

Borowiec, 1987, DNA supercoiling promotes formation of a bent repression loop in lac DNA, J. Mol. Biol., 196, 101, 10.1016/0022-2836(87)90513-4

Bushman, 1988, Turning λ Cro into a transcriptional activator, Cell, 54, 191, 10.1016/0092-8674(88)90551-X

Fried, 1981, Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis, Nucl. Acids Res., 9, 6505, 10.1093/nar/9.23.6505

Foster, 1979, Transposon generated mutations in the mercuric resistance genes of plasmid R100-1, J. Bacteriol., 140, 167, 10.1128/JB.140.1.167-181.1979

Garner, 1981, A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: applications to components of the E. coli lactose operon regulatory system, Nucl. Acids Res., 9, 3047, 10.1093/nar/9.13.3047

Gartenberg, 1988, DNA sequence determinants of CAP-induced bending and protein binding affinity, Nature, 333, 824, 10.1038/333824a0

Grossman, 1984, The htpR gene product of E. coli is a sigma factor for heat shock promoters, Cell, 38, 383, 10.1016/0092-8674(84)90493-8

Guarente, 1982, Mutant λ phage repressor with a specific defect in its positive control function, 79, 2236

Harley, 1987, Analysis of E. coli promoter sequences, Nucl. Acids Res., 15, 2343, 10.1093/nar/15.5.2343

Hayatsu, 1967, The selective degradation of pyrimidines in nucleic acids by permanganate oxidation, Biochem. Biophys. Res. Commun., 29, 556, 10.1016/0006-291X(67)90521-9

Heltzel, 1987, Overexpression and DNA binding properties of the mer-encoded regulatory protein from plasmid NR1 (Tn21), J. Bacteriol., 169, 3379, 10.1128/jb.169.7.3379-3384.1987

Ho, 1983, Bacteriophage λ protein cII binds promoters on the opposite face of the DNA helix from RNA polymerase, Nature, 304, 703, 10.1038/304703a0

Hochschild, 1983, Repressor structure and the mechanism of positive control, Cell, 32, 319, 10.1016/0092-8674(83)90451-8

Huo, 1988, Alternative DNA loops regulate the arabinose operon of Escherichia coli, 85, 5444

Jordan, 1988, Structure of the lambda complex at 2.5 Å resolution: detail of the repressor-operator interactions, Science, 242, 893, 10.1126/science.3187530

Karin, 1987, Metal-responsive elements act as positive modulators of human metallothionein-IIA enhancer activity, Mol. Cell. Biol., 7, 606, 10.1128/MCB.7.2.606

Kirkegaard, 1983, Mapping of single-stranded regions in duplex DNA at the sequence level: single-strand-specific cytosine methylation in RNA polymerase-promoter complexes, 80, 2544

Klotz, 1986

Koudelkae, 1987, Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro, Nature, 326, 886, 10.1038/326886a0

Lee, 1987, Arabinose-induced binding of AraC protein to aral2 activates the araBAD operon promoter, 84, 8814

Levin, 1987, Isolation and properties of transcribing ternary complexes of Escherichia coli RNA polymerase positioned at a single template base, J. Mol. Biol., 196, 85, 10.1016/0022-2836(87)90512-2

Lund, 1987, Role of the merT and merP gene products of transposon Tn501 in the induction and expression of resistance to mercuric ions, Gene, 52, 207, 10.1016/0378-1119(87)90047-3

Lund, 1986, Transcriptional regulation of the mercury-resistance genes of transposon Tn501, J. Gen. Microbiol., 132, 465

Maxam, 1980, Sequencing end-labeled DNA with base-specific chemical cleavages, Meth. Enzymol., 65, 499, 10.1016/S0076-6879(80)65059-9

Meyer, 1975, λ repressor turns off transcription of tis own gene, 72, 4785

Misra, 1984, Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory region and the first two structural genes, 81, 5975

Ni'Bhrian, 1983, Tn5 insertion mutations in the mercuric ion resistance genes derived from plasmid R100, J. Bacteriol., 155, 690, 10.1128/JB.155.2.690-703.1983

O'Halloran, 1989, Metalloregulatory proteins: metal-responsive molecular switches governing gene expression, Vol. 25

O'Halloran, 1987, Metalloregulatory DNA binding protein encoded by the merR gene: isolation and characterization, Science, 235, 211, 10.1126/science.3798107

Poteete, 1982, Control of transcription by the bacteriophage P22 repressor, J. Mol. Biol., 157, 21, 10.1016/0022-2836(82)90511-3

Raibaud, 1984, Positive control of transcription initiation in bacteria, Annu. Rev. Genet., 18, 173, 10.1146/annurev.ge.18.120184.001133

Ronson, 1987, Conserved domains in bacterial regulatory proteins that respond to environmental stimuli, Cell, 49, 579, 10.1016/0092-8674(87)90530-7

Rubin, 1980, Pyrimidine-specific chemical reactions useful for DNA sequencing, Nucl. Acids Res., 8, 4613, 10.1093/nar/8.20.4613

Saxe, 1979, Cooperative binding to DNA of catabolite activator protein of E. coli, Biochemistry, 18, 255, 10.1021/bi00569a003

Seguin, 1987, Regulation in vitro of metal lothionein gene binding factors, Science, 235, 1383, 10.1126/science.3103216

Shanblatt, 1986, The binding of catabolite activator protein and RNA polymerase to the Escherichia coli galactose and lactose promoters probed by alkylation interference studies, J. Biol. Chem., 261, 10885, 10.1016/S0021-9258(18)67470-8

Siebenlist, 1980, E. coli RNA polymerase interacts homologously with two different promoters, Cell, 20, 269, 10.1016/0092-8674(80)90613-3

Spassky, 1985, Changes in the DNA structure of the lac UV5 promoter during formation of an open complex with Escherichia coli RNA polymerase, Biochemistry, 24, 2723, 10.1021/bi00332a019

Stefano, 1982, Spacer mutations in the lac p5 promoter, 79, 1069

Straney, 1985, Intermediates in transcription initiation from the E. coli lac UV5 promoter, Cell, 43, 449, 10.1016/0092-8674(85)90175-8

Straney, 1987, Kinetics of the stages of transcription initiation at the Escherichia coli lac UV5 promoter, Biochemistry, 26, 5063, 10.1021/bi00390a027

Summers, 1986, Organization, expression, and evolution of genes for mercury resistance, Annu. Rev. Microbiol., 40, 607, 10.1146/annurev.mi.40.100186.003135

Teo, 1986, The intracellular signal for induction of resistance to alkylating agents in E. coli, Cell, 45, 315, 10.1016/0092-8674(86)90396-X

Travers, 1987, DNA wrapping and writhing, Nature, 327, 280, 10.1038/327280a0

Tullius, 1986, Hydroxyl radical “footprinting”: high-resolution information about DNA-protein contacts and application to lambda repressor and cro protein, 83, 5469

Tullius, 1987, Hydroxyl radical footprinting: a high resolution method for mapping protein-DNA contacts, Meth. Enzymol., 155, 537, 10.1016/0076-6879(87)55035-2

Walsh, 1988, Molecular basis of bacterial resistance to organomercurial and inorganic mercuric salts, FASEB J., 2, 124, 10.1096/fasebj.2.2.3277886

Wray, 1981, Silver staining of proteins in polyacrylamide gels, Anal. Biochem., 118, 197, 10.1016/0003-2697(81)90179-2