GRP78 secreted by tumor cells stimulates differentiation of bone marrow mesenchymal stem cells to cancer-associated fibroblasts

Biochemical and Biophysical Research Communications - Tập 440 - Trang 558-563 - 2013
Yanan Peng1, Zongwei Li1, Zhuoyu Li1,2
1Institute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China
2College of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, China

Tài liệu tham khảo

Dvorak, 1991, Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies, Cancer Cell, 3, 77 Spaeth, 2009, Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression, PLoS One, 4, e4992, 10.1371/journal.pone.0004992 Quante, 2011, Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth, Cancer Cell, 19, 257, 10.1016/j.ccr.2011.01.020 Pietras, 2010, Hallmarks of cancer: interactions with the tumor stroma, Exp. Cell Res., 316, 1324, 10.1016/j.yexcr.2010.02.045 Mao, 2013, Stromal cells in tumor microenvironment and breast cancer, Cancer Metastasis Rev., 32, 303, 10.1007/s10555-012-9415-3 Cuiffo, 2012, Mesenchymal stem cells in tumor development: emerging roles and concepts, Cell Adhes. Migr., 6, 220, 10.4161/cam.20875 Östman, 2009, Cancer-associated fibroblasts and tumor growth–bystanders turning into key players, Curr. Opin. Genet. Dev., 19, 67, 10.1016/j.gde.2009.01.003 Kalluri, 2006, Fibroblasts in cancer, Nat. Rev. Cancer, 6, 392, 10.1038/nrc1877 Orimo, 2005, Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion, Cell, 121, 335, 10.1016/j.cell.2005.02.034 Lee, 2010, CTGF directs fibroblast differentiation from human mesenchymal stem/stromal cells and defines connective tissue healing in a rodent injury model, J. Clin. Invest., 120, 3340, 10.1172/JCI43230 Chamberlain, 2007, Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing, Stem Cells, 25, 2739, 10.1634/stemcells.2007-0197 Shi, 2012, How mesenchymal stem cells interact with tissue immune responses, Trends Immunol., 33, 136, 10.1016/j.it.2011.11.004 Chen, 2008, Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing, PLoS One, 3, e1886, 10.1371/journal.pone.0001886 Wu, 2007, Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis, Stem Cells, 25, 2648, 10.1634/stemcells.2007-0226 Phinney, 2007, Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair—current views, Stem Cells, 25, 2896, 10.1634/stemcells.2007-0637 Liu, 2011, Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks, Cancer Res., 71, 614, 10.1158/0008-5472.CAN-10-0538 Kidd, 2009, Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging, Stem Cells, 27, 2614, 10.1002/stem.187 Zhu, 2006, Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo, Exp. Mol. Pathol., 80, 267, 10.1016/j.yexmp.2005.07.004 Ni, 2007, ER chaperones in mammalian development and human diseases, FEBS Lett., 581, 3641, 10.1016/j.febslet.2007.04.045 Haas, 1994, BiP (GRP78), an essential hsp70 resident protein in the endoplasmic reticulum, Experientia, 50, 1012, 10.1007/BF01923455 Lee, 2001, The glucose-regulated proteins: stress induction and clinical applications, Trends Biochem. Sci., 26, 504, 10.1016/S0968-0004(01)01908-9 Lee, 2007, GRP78 induction in cancer: therapeutic and prognostic implications, Cancer Res., 67, 3496, 10.1158/0008-5472.CAN-07-0325 Li, 1826, Glucose regulated protein 78: a critical link between tumor microenvironment and cancer hallmarks, Biochim. Biophys. Acta, 2012, 13 Li, 2013, Cell-surface GRP78 facilitates colorectal cancer cell migration and invasion, Int. J. Biochem. Cell Biol., 10.1016/j.biocel.2013.02.002 Dong, 2008, Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development, Cancer Res., 68, 498, 10.1158/0008-5472.CAN-07-2950 Lee, 2006, GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer, Cancer Res., 66, 7849, 10.1158/0008-5472.CAN-06-1660 Mishra, 2008, Carcinoma-associated fibroblast–like differentiation of human mesenchymal stem cells, Cancer Res., 68, 4331, 10.1158/0008-5472.CAN-08-0943 Allinen, 2004, Molecular characterization of the tumor microenvironment in breast cancer, Cancer Cell, 6, 17, 10.1016/j.ccr.2004.06.010 Hayward, 2001, Malignant transformation in a nontumorigenic human prostatic epithelial cell line, Cancer Res., 61, 8135 Olumi, 1999, Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium, Cancer Res., 59, 5002 Udagawa, 2006, Analysis of tumor-associated stromal cells using SCID GFP transgenic mice: contribution of local and bone marrow-derived host cells, FASEB J., 20, 95, 10.1096/fj.04-3669com Gu, 2012, Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-β/Smad pathway, PLoS One, 7, e52465, 10.1371/journal.pone.0052465 Jotzu, 2010, Adipose tissue-derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor-derived factors, Anal. Cell. Pathol., 33, 61, 10.1155/2010/695162 Jeon, 2008, Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast-like cells, Stem Cells, 26, 789, 10.1634/stemcells.2007-0742 Cho, 2011, Exosomes from ovarian cancer cells induce adipose tissue-derived mesenchymal stem cells to acquire the physical and functional characteristics of tumor-supporting myofibroblasts, Gynecol. Oncol., 123, 379, 10.1016/j.ygyno.2011.08.005 Condon, 2005, The role of the stromal microenvironment in prostate cancer, Semin. Cancer Biol., 15, 132, 10.1016/j.semcancer.2004.08.002 Arap, 2004, Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands, Cancer Cell, 6, 275, 10.1016/j.ccr.2004.08.018 Misra, 2009, Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis, Mol. Cancer Ther., 8, 1350, 10.1158/1535-7163.MCT-08-0990 de Ridder, 2011, Autoantibodies against cell-surface GRP78 promote tumor growth in a murine model of melanoma, Melanoma Res., 10.1097/CMR.0b013e3283426805 Kern, 2009, GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib, Blood, 114, 3960, 10.1182/blood-2009-03-209668