Investigations of excess environmental risks around putative sources: Statistical problems and a proposed test

Statistics in Medicine - Tập 7 Số 6 - Trang 649-660 - 1988
Richard A. Stone1
1CSIRO Division of Mathematics & Statistics, Private Bag 10, Clayton, Victoria 3168, Australia

Tóm tắt

AbstractIndividual reactions to a report which identifies an excess of risk near a putative source are determined mainly by some quoted significance level. One reaction, involving a commonly used ‘coincidence’ argument is given a simple Bayesian explanation. It is argued that interpretations of such reports should if possible allow both for data selection and for uncertainty in the null expectations underlying the significance levels. Tests are proposed, based on the first isotonic regression estimator under an order restriction, which allow for the effects of selecting a study region in the light of the data and have a simple form. Data on cancer incidence around two nuclear plants are used to illustrate.

Từ khóa


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Statistics in Medicine

Tập 7 Số 6

649-660

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