Carbonate-doped hydroxyapatite
Tóm tắt
A hydroxyapatite slurry was prepared by stirring into water a stoichiometric mixture of tricalcium phosphate and calcium hydroxide until the solid content was 50 wt%. Samples were then prepared by slip casting, drying and firing in vacuum at 1000 to 1300° C for 1 h. The fired samples were crushed and soaked in ordinary mineral water for up to 2 months and examined by differential thermal analysis and thermogravimetry, infrared spectroscopy, X-ray diffraction, scanning electron microscopy and energy-dispersive X-ray analysis, and direct-current plasma emission spectroscopy. One phosphate ion was found to be replaced by carbonate and practically all hydroxide by water, regardless of heat treatment. The infrared spectra showed a close resemblance to that obtained from natural bone.
Tài liệu tham khảo
C. P. A. T. KLEIN, A. A. DRIESSEN, K. DE GROOT and A. VAN DEN HOOFF,J. Biomed. Mater. Res. 17 (1983) 769.
K. DE GROOT, R. G. T. GEESINK, J. G. C. WOLKE and C. P. A. T. KLEIN, in Transactions of the 3rd World Biomaterials Congress, Kyoto, Japan, April 1988, Vol. XI, (Free University, Amsterdam) p. 306.
R. M. BILTZ and E. D. PELLEGRINO,J. Dent. Res. 62 (1983) 1190.
D. G. A. NELSON, ibid.60C (1981) 1622.
D. G. A. NELSON, J. D. B. FEATHERSTONE, J. F. DUNCAN and T. W. CUTRESS,Caries Res. 17 (1983) 200.
L. G. ELLIES, J. M. CARTER, J. R. NATIELLA, J. D. B. FEATHERSTONE and D. G. A. NELSON,J. Biomed. Mater. Res. 22 (1988) 137.
D. McCONNELL, “Apatite: Its Crystal Chemistry, Mineralogy, Utilization, and Geologic and Biologic Occurrences”, 1st Edn (Springer-Verlag, New York, 1973) p. 39.
L. G. ELLIES, D. G. A. NELSON and J. D. B. FEATHERSTONE,J. Biomed. Mater. Res. 22 (1988) 541.
K. C. BLAKESLEE and R. A. CONDRATE, Sr,J. Amer. Ceram. Soc. 54 (1971) 559.
F. C. M. DRIESSENS,Bull. Soc. Chim. Belg. 89 (1980) 663.
J. E. HARRIES, S. S. HASNAIN and J. S. SHAH,Calcif. Tissue Int. 41 (1987) 346.