The Effect of Pregnancy on Renal Function: Physiology and Pathophysiology

The American Journal of the Medical Sciences - Tập 303 Số 3 - Trang 184-205 - 1992
Eugene Dafnis1, Sandra Sabatini2
1Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock 79430.
2Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas

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Tài liệu tham khảo

Ueland, 1969, Maternal cardiovascular dynamics: IV. The influence of gestational age on the maternal cardiovascular response to posture and exercise, Am J Obstet Gynecol, 104, 856, 10.1016/0002-9378(69)90637-1

Metcalfe, 1974, Maternal cardiovascular adjustments to pregnancy, Prog Cardiovasc Dis, 16, 363, 10.1016/0033-0620(74)90028-0

MacGillivray, 1969, Blood pressure survey in pregnancy, Clin Sci, 37, 395

Gant, 1973, A study of angiotensin II pressor response throughout primigravida pregnancy, J Clin Invest, 52, 2682, 10.1172/JCI107462

Chesley, 1972, Plasma and red cell volumes during pregnancy, Am J Obstet Gynecol, 112, 440, 10.1016/0002-9378(72)90493-0

Davison, 1980, Renal hemodynamics and tubular function in normal human pregnancy, Kidney Int, 18, 152, 10.1038/ki.1980.124

Davison, 1984, Changes in renal hemodynamics and tubular function induced by normal human pregnancy, Seminars in Nephrology, 4, 198

Baylis, 1987, The determinants of renal hemodynamics in pregnancy, Am J Kidney Dis, 9, 260, 10.1016/S0272-6386(87)80119-1

Sims, 1958, Serial studies of renal function during pregnancy and the puerperium in normal women, J Clin invest, 37, 1764, 10.1172/JCI103769

Ronco, 1988, Renal functional reserve in pregnancy, Nephrology Dialysis Transplantation, 2, 157

Barron, 1989, Effect of oral protein loading in pregnant and post partum women: How well does it predict renal reserve? abstract, Clin Exp Hypertens [A], B8, 208

Bosch, 1984, Short term protein loading in the assessment of patients with renal disease, Am J Med, 77, 873, 10.1016/0002-9343(84)90529-1

Chesley, 1978

Baylis, 1980, The mechanism of the increase in glomerular filtration rate in the twelve-day pregnant rat, J Physiol, 305, 405, 10.1113/jphysiol.1980.sp013372

Walker, 1985, Single nephron function during prolactin-induced pseudopregnancy in the rat, J Endocrinol, 107, 127, 10.1677/joe.0.1070127

Baylis, 1986, Effects of chronic prolactin administration on renal hemodynamics in the rat, Endocrinology, 117, 722, 10.1210/endo-117-2-722

Baylis, 1986, Angiotensin II inhibition on blood pressure and renal hemodynamics in pregnant rats, Am J Physiol, 250, F308

Lindheimer, 1987, Renal physiology in pregnancy, 2017

Atherton, 1988, Sodium and water reabsorption in the proximal and distal nephron in conscious pregnant rats and third trimester women, J Physiol, 396, 457, 10.1113/jphysiol.1988.sp016972

Garland, 1982, Micropuncture study of changes in glomerular filtration and ion and water handling by the rat kidney during pregnancy, J Physiol, 329, 389, 10.1113/jphysiol.1982.sp014309

Churchill, 1982, Renal function in the term pregnant rat. A micropuncture study, Renal Physiol (Basel), 5, 1

Smeaton, 1977, Study of aldosterone levels in plasma during pregnancy, J Clin Endocrinol Metab, 44, 1, 10.1210/jcem-44-1-1

Kumar, 1959, Aldosterone excretion and tissue electrolytes in normal pregnancy and preeclampsia, Lancet, 1, 541, 10.1016/S0140-6736(59)92309-8

Nolten, 1978, Desoxy-corticosterone in normal pregnancy: I. Sequential studies of the secretory patterns of desoxycorticosterone, aldosterone, and cortisol, Am J Obstet Gynecol, 132, 414, 10.1016/0002-9378(78)90777-9

Winkel, 1980, Conversion of plasma progesterone to deoxycorticosterone in men, nonpregnant, and pregnant women, and adrenalectomized subjects. Evidence for steroid 21-hydroxylase activity in nonadrenal tissues, J Clin Invest, 66, 803, 10.1172/JCI109918

Ehelick, 1972, Effect of administered mineralocorticoids or ACTH in pregnant women. Attenuation of kaliuretic influence of mineralocorticoids during pregnancy, J Clin Invest, 51, 1301, 10.1172/JCI106926

Digman, 1956, Effect of estrogens on renal hemodynamics and excretion of electrolytes in human subjects, J Clin Endocrinol Metab, 16, 1032, 10.1210/jcem-16-8-1032

O’Connell, 1969, Unbound plasma cortisol in pregnant and Enovid-E® treated women as determined by ultrafiltration, J Clin Endocrinol Metab, 29, 563, 10.1210/jcem-29-4-563

Lindheimer, 1988, The kidney in pregnancy, 1253

Chesley, 1964, The effect of posture on renal function in late pregnancy, Am J Obstet Gynecol, 89, 754, 10.1016/0002-9378(64)90178-4

Oparil, 1975, Effect of progesterone on renal sodium handling in man: Relation to aldosterone excretion and plasma renin activity, Clin Sci Mol Med, 44, 139

Cusson, 1985, Plasma concentration of atrial natriuretic factor in normal pregnancy, N Engl J Med, 313, 1230, 10.1056/NEJM198511073131919

Rutherford, 1987, Release of atrial natriuretic peptide during pregnancy and immediate Puerperium, Lancet, 1, 928, 10.1016/S0140-6736(87)92910-2

Hevet, 1988, Ouabain-like natriuretic factor and atrial natriuretic factor in pregnancy, Kidney Int, 34, S89

Hytten, 1971

Pitkin, 1988, Calcium and the parathyroid glands, 271

Kumar, 1979, Elevated 1,25 hydroxyvitamin D plasma levels in normal human pregnancy and lactation, J Clin Invest, 63, 342, 10.1172/JCI109308

Pitkin, 1979, Calcium metabolism in pregnancy: A longitudinal study, Am J Obstet Gynecol, 133, 781, 10.1016/0002-9378(79)90115-7

Paller, 1987, Fluid and electrolyte metabolism in pregnancy, 851

Semple, 1974, Serial studies of the renal clearance of urate and inulin during pregnancy and after the Puerperium in normal women, Clin Sci Mol Med, 47, 559

Seitchik, 1956, The metabolism of urate in preeclampsia, Am J Obstet Gynecol, 72, 40, 10.1016/S0002-9378(16)37509-3

Davison, 1987, Overview: Kidney function in pregnant women, Am J Kidney Dis, 9, 248, 10.1016/S0272-6386(87)80117-8

Dunlop, 1977, The effect of normal pregnancy upon the renal handling of uric acid, Br J Obstet Gynaecol, 84, 13, 10.1111/j.1471-0528.1977.tb12459.x

Coustan, 1988, Diabetes mellitus, 34

Christensen, 1958, Tubular reabsorption of glucose during pregnancy, Scand J Clin Lab Invest, 10, 364, 10.3109/00365515809051238

Atherton, 1983, Renal function in pregnancy, Clin Sci, 65, 449, 10.1042/cs0650449

Welsh, 1960, The mechanisms of renal glucosuria in pregnancy, Diabetes, 9, 363, 10.2337/diab.9.5.363

Davison, 1975, The effect of pregnancy on the renal handling of glucose, Br J Obstet Gynaecol, 82, 374, 10.1111/j.1471-0528.1975.tb00652.x

Bishop, 1981, Effects of pregnancy on glucose reabsorption by the proximal convoluted tubule in the rat, J Physiol, 319, 271, 10.1113/jphysiol.1981.sp013907

Bishop, 1983, Glucose handling by distal portions of the nephron during pregnancy in the rat, J Physiol, 336, 131, 10.1113/jphysiol.1983.sp014572

Daniel, 1974, Carbohydrate metabolism in pregnancy. XI. Response to plasma glucagon to over-night fast and oral glucose during normal pregnancy and in gestational diabetes, Diabetes, 23, 771, 10.2337/diab.23.9.771

Kuhl, 1976, Plasma glucagon and the insulin: Glucagon ratio in gestational diabetes, Diabetes, 25, 16, 10.2337/diab.25.1.16

Hytten, 1972, The amino aciduria of pregnancy, The Journal of Obstetrics and Gynaecology of the British Commonwealth, 79, 424, 10.1111/j.1471-0528.1972.tb14180.x

Wullraff, 1950, Urinary excretion of amino acids in pregnancy, J Clin Invest, 29, 1542, 10.1172/JCI102395

Zinneman, 1967, Urinary amino acid in pregnancy following progesterone and estrogen, J Clin Endocrinol Metab, 27, 397, 10.1210/jcem-27-3-397

Ferris, 1988, Renal diseases, 277

Lyons, 1959, The sensitivity of the respiratory center in pregnancy and after the administration of progesterone, Trans Assoc Am Physicians, 72, 173

Assali, 1955, Renal response to ammonium chloride acidosis in normal and toxemic pregnancies, J App Physiol, 7, 367, 10.1152/jappl.1955.7.4.367

Lim, 1976, Acid-base regulation in pregnancy, Am J Physiol, 231, 1764, 10.1152/ajplegacy.1976.231.6.1764

Davison, 1981, Plasma osmolality and urinary concentration and dilution during and after pregnancy: Evidence that lateral recumbency inhibits maximal concentration ability, Br J Obstet Gynaecol, 88, 472, 10.1111/j.1471-0528.1981.tb01019.x

Lindheimer, 1989, Osmoregulation of thirst and vasopressin release in pregnancy, Am J Physiol, 257, F159

Davison, 1984, Altered osmotic thresholds for vasopressin secretion and thirst in human pregnancy, Am J Physiol, 246, F105

Davison, 1988, Serial evaluation of vasopressin and thirst in human pregnancy. Role of human chorionic gonadotropin on the osmoregulatory changes of gestation, J Clin Invest, 81, 798, 10.1172/JCI113386

Forsling, 1981, Variations in plasma concentrations of vasopressin during the menstrual cycle, J Endocrinol, 89, 263, 10.1677/joe.0.0890263

Spruce, 1985, Variation in osmoregulation of arginine vasopressin during the human menstrual cycle, Clin Endocrinol, 22, 37, 10.1111/j.1365-2265.1985.tb01062.x

Skowsky, 1979, Effects of sex steroid hormones on arginine vasopressin in intact and castrated male and female rats, Endocrinology, 104, 106, 10.1210/endo-104-1-105

Barron, 1986, Effect of ovarian sex steroids on osmoregulation and vasopressin secretion in the rat, Am J Physiol, 250, E352

Lindheimer, 1987, Water homeostasis and vasopressin release during rodent human gestation, Am J Kidney Dis, 9, 270, 10.1016/S0272-6386(87)80121-X

Schrier, 1988, Pathogenesis of sodium and water retention in high output and low output cardiac failure, nephrotic syndrome, cirrhosis, and pregnancy. (Second of two parts.), N Engl J Med, 319, 1127, 10.1056/NEJM198810273191705

Robertson, 1976, The interaction of blood osmolality and blood volume in regulating plasma vasopressin in man, J Clin Endocrinol Metab, 42, 613, 10.1210/jcem-42-4-613

Gallery, 1977, Control of sodium excretion in human pregnancy, Am J Kidney Dis, 9, 290, 10.1016/S0272-6386(87)80124-5

Schrier, 1987, Pregnancy: An overfill or underfill state, Am J Kidney Dis, 9, 284, 10.1016/S0272-6386(87)80123-3

Symonds, 1983, Renin-angiotensin in normal and hypertensive pregnancy, 91

Goodman, 1982, Prostacyclin production during pregnancy: Comparison of production during normal pregnancy and pregnancy complicated by hypertension, Am J Obstet Gynecol, 142, 817, 10.1016/S0002-9378(16)32525-X

Conrand, 1986, Evidence against the hypothesis that prostaglandins are the vasodepressor agents of pregnancy: Serial studies in chronically instrumented conscious rats, J Clin Invest, 77, 236, 10.1172/JCI112282

Venuto, 1982, Prostaglandin E2, plasma renin activity, and renal function throughout rabbit pregnancy, J Lab Clin Med, 99, 239

Whalen, 1978, Plasma prostaglandins in pregnancy, Obstet Gynecol, 51, 52

Paller, 1987, Decreased pressor responsiveness in pregnancy: Studies in experimental animals, Am J Kidney Dis, 9, 308, 10.1016/S0272-6386(87)80127-0

Baylis, 1985, Tubuloglomerular feedback activity in virgin and 12-day-pregnant rats, Am J Physiol, 249, F169

Guzick, 1987, Risk factors for the occurrence of pregnancy-induced hypertension, Clin Exp Hypertens [A] B, 6, 281

First, 1988, Pregnancy and renal disease, 2533

Lindheimer, 1989, Preeclampsia: Pathophysiology, diagnosis, and management, Annu Reu Med, 40, 233, 10.1146/annurev.me.40.020189.001313

Gant, 1974, A clinical test useful for predicting the development of acute hypertension in pregnancy, Am J Obstet Gynecol, 120, 1, 10.1016/0002-9378(74)90170-7

Lindheimer, 1983, Hypertension in pregnancy, 887

Annat, 1978, Maternal and fetal plasma renin and dopamine β-hydroxylase activities in toxemic pregnancy, Obstet Gynecol, 52, 219

Broughton Pipkin, 1982, The renin-angiotensin system in pregnancy: Why bother?, Br J Obstet Gynaecol, 89, 591, 10.1111/j.1471-0528.1982.tb04708.x

Lindheimer, 1989, Diagnosis and management of hypertension complicating pregnancy, Am J Kidney Dis, 13, 17

Makila, 1984, Evidence that prostacyclin deficiency is a specific feature in preeclampsia, Am J Obstet Gynecol, 148, 772, 10.1016/0002-9378(84)90564-7

Moodley, 1984, Central venous concentrations of immunoreactive prostaglandins E, F, and 6-ketoprostaglandin F1 in eclampsia, Br Med J, 288, 1487, 10.1136/bmj.288.6429.1487

Remuzzi, 1980, Reduced umbilical and placental vascular prostacyclin in severe preeclampsia, Prostaglandins, 20, 105, 10.1016/0090-6980(80)90010-6

Walsh, 1985, Preeclampsia: An imbalance in placental prostacyclin and thromboxane production, Am J Obstet Gynecol, 152, 335, 10.1016/S0002-9378(85)80223-4

Thorp, 1986, Vasoconstrictive effects of leukotriene (LT5) compared with thromboxane A2 in perfused human placental cotyledon, abstract

Beaufils, 1985, Prevention of preeclampsia by early antiplatelet therapy, Lancet, 1, 840, 10.1016/S0140-6736(85)92207-X

Gastaldi, 1988, Prevention of preeclampsia and possible correlation with physiopathology, Clin Exp Hypertens B, 7, 139, 10.3109/10641958809023510

Masotti, 1979, Differential inhibition of prostacyclin production and platelet aggregation by aspirin, Lancet, 2, 1213, 10.1016/S0140-6736(79)92334-1

Schiff, 1989, The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of thromboxane A2 to prostacyclin in relatively high risk pregnancies, N Engl J Med, 321, 351, 10.1056/NEJM198908103210603

Benigni, 1989, Effect of low dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension, N Engl J Med, 321, 357, 10.1056/NEJM198908103210604

Ramos, 1987, Effect of low-dose aspirin on angiotensin II pressor response in human pregnancy, Am J Obstet Gynecol, 156, 193, 10.1016/0002-9378(87)90236-5

Gant, 1980, Control of vascular responsiveness during human pregnancy, Kidney Int, 18, 253, 10.1038/ki.1980.133

Ferris, 1988, Toxemia and hypertension, 1

Groenendijk, 1984, Hemodynamic measurements in preeclampsia: Preliminary observations, Am J Obstet Gynecol, 150, 232, 10.1016/S0002-9378(84)90357-0

Hankins, 1984, Longitudinal evaluation of hemodynamic changes in eclampsia, Am J Obstet Gynecol, 150, 506, 10.1016/S0002-9378(84)90429-0

Lindheimer, 1991, Introduction and overview, Am J Kidney Dis, 17, 95, 10.1016/S0272-6386(12)81110-3

Mochizuki, 1991, Vascular reactivity in normal and abnormal gestation, Am J Kidney Dis, 17, 139, 10.1016/S0272-6386(12)81118-8

Ignarro, 1989, Endothelium-derived nitric oxide: Actions and properties, FASEB J, 3, 31, 10.1096/fasebj.3.1.2642868

Rees, 1989, Role of endothelium-derived nitric oxide in the regulation of blood pressure, Proc Natl Acad Sci USA, 86, 3375, 10.1073/pnas.86.9.3375

Weiner, 1987, The clinical spectrum of preeclampsia, AmJ Kidney Dis, 9, 312, 10.1016/S0272-6386(87)80128-2

Goodlin, 1976, Severe preeclampsia: Another great imitator, Am J Obstet Gynaecol, 125, 747, 10.1016/0002-9378(76)90841-3

Arulkumaran, 1985, Transient blindness associated with pregnancy-induced hypertension, Case reports, Br J Obstet Gynaecol, 92, 847, 10.1111/j.1471-0528.1985.tb03058.x

Krieger, 1984, Reversible tubular lesion in pregnancy-induced hypertension detected by urinary β2-microglobulin, Obstet Gynecol, 63, 533

Fisher, 1981, Hypertension in pregnancy: Clinical-pathological correlations and remote prognosis, Medicine, 60, 267, 10.1097/00005792-198107000-00002

Taufield, 1987, Hypocalciuria in preeclampsia, N Engl J Med, 316, 715, 10.1056/NEJM198703193161204

Varma, 1982, Serum uric acid levels as an index of fetal prognosis in pregnancies complicated by preexisting hypertension and preeclampsia of pregnancy, Int J Gynaecol Obstet, 20, 401, 10.1016/0020-7292(82)90200-4

Gant, 1977, A prospective study of angiotensin II pressor responsiveness in pregnancies complicated by chronic essential hypertension, Am J Obstet Gynecol, 127, 369, 10.1016/0002-9378(77)90492-6

Weiner, 1985, Antithrombin III activity in women with hypertension during pregnancy, Obstet Gynecol, 65, 301

Entman, 1987, Increased levels of carboxy hemoglobin and serum iron as an indication of increased red cell turnover in preeclampsia, Am J Obstet Gynecol, 156, 1169, 10.1016/0002-9378(87)90134-7

Foidart, 1966, Antibodies to laminin in preeclampsia, Kidney Int, 29, 1050, 10.1038/ki.1986.106

Gaber, 1987, Pregnancy-induced nephropathy: The significance of focal segmental glomerulosclerosis, Am J Kidney Dis, 9, 317, 10.1016/S0272-6386(87)80129-4

Surian, 1984, Glomerular disease and pregnancy, Nephron, 36, 101, 10.1159/000183126

Schenker, 1982, Pheochromocytoma and pregnancy: An update appraisal, Aust NZ J Obstet Gynaecol, 22, 1, 10.1111/j.1479-828X.1982.tb01388.x

Packham, 1987, Renal biopsy: Indications and complications in pregnancy, Br J Obstet Gynaecol, 94, 935, 10.1111/j.1471-0528.1987.tb02266.x

Lindheimer, 1984, Renal biopsy during pregnancy: “To b…or not to b…”?, Br J Obstet Gynaecol, 94, 932, 10.1111/j.1471-0528.1987.tb02265.x

Schewitz, 1962, Preeclampsia and eclampsia in early pregnancy, Am J Obstet Gynecol, 84, 1330, 10.1016/S0002-9378(16)35743-X

Pritchard, 1980, Management of preeclampsia and eclampsia, Kidney Int, 18, 259, 10.1038/ki.1980.134

Watson, 1986, Magnesium sulfate: Rationale for its use in preeclampsia, Proc Natl Acad Sci USA, 83, 1075, 10.1073/pnas.83.4.1075

Thurnau, 1987, Cerebrospinal fluid levels of magnesium in patients with preeclampsia after treatment with magnesium sulfate: A preliminary report, Am J Obstet Gynecol, 157, 1435, 10.1016/S0002-9378(87)80239-9

Cree, 1973, Diazepam in labour: Its metabolism and effect on the clinical condition of thermogenesis of the newborn, Br Med J, 4, 251, 10.1136/bmj.4.5887.251

Cunningham, 1989, Prevention of preeclampsia—a reality, N Engl J Med, 321, 606, 10.1056/NEJM198908313210908

Weksler, 1983, Eicosanoids and the endothelium: Studies in vivo and in vitro, 243

Collins, 1985, Overview of randomized trials of diuretics in pregnancy, Br Med J, 290, 17, 10.1136/bmj.290.6461.17

Gallery, 1981, Antihypertensive effects of volume expansion in pregnancy-associated hypertension, Aust NZ J Med, 11, 20

Strauss, 1980, Hemodynamic monitoring of cardiogenic pulmonary edema complicating toxemia in pregnancy, Obstet Gynecol, 55, 170

Newman, 1979, Diazoxide for the acute control of severe hypertension complicating pregnancy. A pilot study, Obstet Gynecol, 53, S50

Vink, 1980, Effect of hydralazine on the fetus in the treatment of the maternal hypertension, Obstet Gynecol, 55, 519

Lunell, 1982, Acute effect of an antihypertensive drug, labetalol, on uteroplacental blood flow, Br J Obstet Gynaecol, 89, 640, 10.1111/j.1471-0528.1982.tb04719.x

Karlsson, 1982, Blood flow of the reproductive system in renal hypertensive rats during pregnancy, Am J Obstet Gynecol, 142, 1039, 10.1016/0002-9378(82)90790-6

Suonio, 1981, Acute effects of hydralazine mesylate, furosemide and metoprolol on maternal hemodynamics in pregnancy induced hypertension, Am J Obstet Gynecol, 155, 122, 10.1016/0002-9378(86)90093-1

Lewis, 1977, Placental transfer and fetal toxicity of sodium nitroprusside, abstract, Gynecol Obstet Invest, 8, 46

Stempel, 1982, Use of sodium nitroprusside in complications of gestational hypertension, Obstet Gynecol, 60, 533

Jouppila, 1986, Labetalol does not alter the placental and fetal blood flow or maternal prostanoids in preeclampsia, Br J Obstet Gynaecol, 93, 543, 10.1111/j.1471-0528.1986.tb07951.x

Garden, 1982, Intravenous labetalol and intravenous hydralazine in severe hypertension in pregnancy, lin Exp Hypertens, B1, 371

Ashe, 1987, Comparison of labetalol and dihydralazine in hypertensive emergencies of pregnancy, S Afr Med J, 71, 354

Mabie, 1987, A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy, Obstet Gynecol, 70, 328

Kjellmer, 1984, Maternal beta-adrenoceptor reduces fetal tolerance to asphyxia, Acta Obstet Gynecol Scand [Suppl], 118, S75, 10.3109/00016348409157128

Allen, 1987, Acute effects of nitrendipine in pregnancy-induced hypertension, Br J Obstet Gynaecol, 94, 222, 10.1111/j.1471-0528.1987.tb02358.x

Walters, 1984, Treatment of severe pregnancy associated hypertension with the calcium antagonist nifedipine, Br J Obstet Gynaecol, 91, 330, 10.1111/j.1471-0528.1984.tb05918.x

Parisi, 1989, Fetal vascular responses to maternal nicardipine administration in the hypertensive ewe, Am J Obstet Gynecol, 161, 1035, 10.1016/0002-9378(89)90779-5

Rosa, 1989, Neonatal anuria with maternal angiotensin-converting enzyme inhibition, Obstet Gynecol, 74, 371

Katz, 1985, Does pregnancy aggravate primary glomerular disease?, Am J Kidney Dis, 6, 261, 10.1016/S0272-6386(85)80185-2

Davison, 1985, Pregnancy in women with renal disease and renal transplantation, Proc Eur Dial Transplant Assoc, 22, 439

Hayslett, 1985, Pregnancy does not exacerbate primary glomerular diseases, Am J Kidney Dis, 6, 273, 10.1016/S0272-6386(85)80187-6

Bear, 1976, Pregnancy in patients with renal disease, Obstet Gynecol, 48, 13

Hou, 1987, Pregnancy in women requiring dialysis for renal failure, Am J Kidney Dis, 9, 368, 10.1016/S0272-6386(87)80139-7

Ahallah, 1985, 185

Nageotte, 1988, Pregnancy outcome in women requiring chronic hemodialysis, Obstet Gynecol, 72, 456

Kioko, 1983, Successful pregnancy in a diabetic patient treated with continuous ambulatory peritoneal dialysis, Diabetes Care, 6, 298, 10.2337/diacare.6.3.298

Davison, 1991, Dialysis, transplantation and pregnancy, Am J Kidney Dis, 17, 127, 10.1016/S0272-6386(12)81116-4

Davison, 1987, Renal transplantation and pregnancy, Am J Kidney Dis, 9, 374, 10.1016/S0272-6386(87)80140-3

Lewis, 1983, Successful pregnancy in a renal transplant recipient taking cyclosporin A, Br Med J, 286, 603, 10.1136/bmj.286.6365.603

Pickrell, 1988, Pregnancy after transplantation: Severe intrauterine growth retardation during treatment with cyclosporin A, Br Med J, 296, 825, 10.1136/bmj.296.6625.825

Williams, 1987, Pregnancy after transplantation, Br Med J, 296, 1400, 10.1136/bmj.296.6633.1400-b

Davison, 1984, Pregnancy in women with renal allografts, Seminars in Nephrology, 4, 240

Kitzmiller, 1981, Diabetic nephropathy and perinatal outcome, Am J Obstet Gynecol, 141, 741, 10.1016/0002-9378(81)90698-0

Hayslett, 1987, Effect of diabetic nephropathy in pregnancy, Am J Kidney Dis, 9, 344, 10.1016/S0272-6386(87)80134-8

McCance, 1989, Urinary albumin excretion in diabetic pregnancy, Diabetologia, 32, 236, 10.1007/BF00285290

Bobrie, 1987, Pregnancy in lupus nephritis and related disorders, Am J Kidney Dis, 9, 339, 10.1016/S0272-6386(87)80133-6

Cameron, 1985, The outcome of pregnancy in patients with lupus nephritis, Proc Eur Dial Transplant Assoc, 22, 487

Hayslett, 1980, Effect of pregnancy in patients with lupus nephropathy, Kidney Int, 18, 207, 10.1038/ki.1980.129

Abramowsky, 1980, Decidual vasculopathy of the placenta in lupus erythematosus, N Engl J Med, 303, 668, 10.1056/NEJM198009183031204

Milutinovic, 1983, Fertility and pregnancy complications in women with autosomal dominant polycystic kidney disease, Obstet Gynecol, 61, 566

Mictheson, 1977, Clinical aspects of polycystic disease of the kidneys, Br Med J, 1, 1196, 10.1136/bmj.1.6070.1196

Kincaid-Smith, 1967, Kidney disease and pregnancy, Med J Aust, 2, 1155, 10.5694/j.1326-5377.1967.tb27360.x

Kincaid-Smith, 1987, Renal disease in pregnancy. Three controversial areas: Mesangial IgA nephropathy, focal glomerular sclerosis (focal and segmental hyalinosis and sclerosis), and reflux nephropathy, Am J Kidney Dis, 9, 328, 10.1016/S0272-6386(87)80131-2

Jungers, 1986, Chronic kidney disease and pregnancy, Adv Nephrol, 15, 103

Hankins, 1985, Acute urinary tract infections in pregnancy, Clin Obstet Gynecol, 28, 266, 10.1097/00003081-198528020-00004

Fairley, 1966, The site of infection in pregnancy bacteriuria, Lancet, 1, 939, 10.1016/S0140-6736(66)90944-5

Anonymous, 1985, Urinary tract infection during pregnancy, Lancet, 2, 190

Zinner, 1979, Bacteriuria and babies revisited, N Engl J Med, 300, 853, 10.1056/NEJM197904123001510

Kutz, 1989, Kidney disease and hypertension in pregnancy, 1003

VanDorsten, 1986, Office diagnosis of asymptomatic bacteriuria in pregnant women, Am J Obstet Gynecol, 155, 777, 10.1016/S0002-9378(86)80019-9

Pedler, 1987, Management of bacteriuria in pregnancy, Drugs, 3, 413, 10.2165/00003495-198733040-00005

McNeely, 1987, Treatment of urinary tract infections during pregnancy, Clin Obstet Gynecol, 13, 480

Harris, 1974, Prevention of recurrent pyelonephritis during pregnancy, Obstet Gynecol, 44, 637

Jakobi, 1987, Single dose antimicrobial therapy in the treatment of asymptomatic bacteriuria in pregnancy, Am J Obstet Gynecol, 156, 1148, 10.1016/0002-9378(87)90129-3

Olsen, 1989, Single-dose versus six-day therapy with sulfamethizole for asymptomatic bacteriuria during pregnancy. A prospective randomized study, Dan Med Bull, 36, 486

Gerstner, 1989, Amoxicillin in the treatment of asymptomatic bacteriuria in pregnancy: A single dose of 3g amoxicillin versus a 4-day of 3 doses 750mg amoxicillin, Gynecol Obstet Invest, 27, 84, 10.1159/000293624

Leveno, 1981, Bladder versus renal bacteriuria during pregnancy. Recurrence after treatment, Am J Obstet Gynecol, 139, 403, 10.1016/0002-9378(81)90316-1

Campbell-Brown, 1987, Is screening for bacteriuria in pregnancy worthwhile?, Br Med J, 294, 1579, 10.1136/bmj.294.6587.1579

Smith, 1987, Is screening for bacteriuria in pregnancy worthwhile?, Br Med J, 295, 445, 10.1136/bmj.295.6595.445-c

Robinson, 1991, “Non-sweet” diabetes of pregnancy, N Eng J Med, 324, 556, 10.1056/NEJM199102213240809

Lindheimer, 1991, Osmotic and volume control of vasopressin release in pregnancy, Am J Kidney Dis, 17, 105, 10.1016/S0272-6386(12)81112-7

Iwasaki, 1991, Aggravation of subclinical diabetes insipidus during pregnancy, N Engl J Med, 324, 522, 10.1056/NEJM199102213240803

Durr, 1987, Diabetes insipidus in pregnancy, Am J Kidney Dis, 9, 276, 10.1016/S0272-6386(87)80122-1

Horowitz, 1985, Renal calculi in pregnancy, Clin Obstet Gynecol, 28, 324, 10.1097/00003081-198528020-00009

Mainkranz, 1987, Nephrolithiasis in pregnancy, Am J Kidney Dis, 9, 354, 10.1016/S0272-6386(87)80136-1

Gambaro, 1988, Increased urinary excretion of glycos-aminoglycans in pregnancy and diabetes mellitus: A protective factor against nephrolithiasis, Nephron, 50, 62, 10.1159/000185120

Folger, 1955, Pain and pregnancy, Obstet Gynecol, 5, 580

Lattanzi, 1980, Urinary calculi in pregnancy, Obstet Gynecol, 56, 462

Jones, 1978, Urolithiasis associated with pregnancy, J Urol, 122, 333, 10.1016/S0022-5347(17)56393-4

Drago, 1982, Management of urinary calculi in pregnancy, Urology, 20, 578, 10.1016/0090-4295(82)90302-8

Armon, 1977, Obstructed labour due to vesical calculus, Br Med J, 2, 498, 10.1136/bmj.2.6085.498

Gregory, 1983, Pregnancy and cystinuria, Lancet, 2, 1158, 10.1016/S0140-6736(83)91213-8

Crawhall, 1967, Dissolution of cystine stones during D-penicillamine treatment of a pregnant patient with cystinuria, Br Med J, 2, 216, 10.1136/bmj.2.5546.216

Pertuiset, 1984, Acute renal failure in pregnancy: An update, Seminars in Nephrology, 4, 232

Grunfeld, 1980, Acute renal failure in pregnancy, Kidney Int, 18, 179, 10.1038/ki.1980.127

Kaplan, 1985, Current concepts: Acute fatty liver of pregnancy, N Engl J Med, 313, 367, 10.1056/NEJM198508083130606

Hayslett, 1985, Postpartum renal failure, N Engl J Med, 312, 1556, 10.1056/NEJM198506133122407

Vitsky, 1969, The hemolytic-uremic syndrome: A study of renal pathologic alterations, Am J Pathol, 57, 627

Grunfeld, 1987, Acute renal failure in pregnancy, Am J Kidney Dis, 9, 359, 10.1016/S0272-6386(87)80137-3