Overcoming drug resistance of MCF-7/ADR cells by altering intracellular distribution of doxorubicin via MVP knockdown with a novel siRNA polyamidoamine-hyaluronic acid complex

Journal of Controlled Release - Tập 163 - Trang 136-144 - 2012
Min Han1, Qing Lv1,2, Xin-Jiang Tang1, Yu-Lan Hu1, Dong-Hang Xu3, Fan-Zhu Li2, Wen-Quan Liang1, Jian-Qing Gao1,4
1Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, P.R. China
2College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, P.R. China
3The Second Affiliated Hospital of Zhejiang University, Hangzhou 310001, P.R. China
4Soft Matter Research Center, Zhejiang University, Hangzhou 310058, P.R. China

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