Long non-coding RNA NEAT1 regulates permeability of the blood-tumor barrier via miR-181d-5p-mediated expression changes in ZO-1, occludin, and claudin-5

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease - Tập 1863 Số 9 - Trang 2240-2254 - 2017
Junqing Guo1,2, Heng Cai3,4, Jian Zheng3,4, Xiaobai Liu3,4, Yunhui Liu3,4, Jun Ma1,2, Zhongyou Que3,4, Wei Gong1,2, Yana Gao1,2, Tao Wei1,2, Yixue Xue1,2
1Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang 110122, People’s Republic of China
2Key Laboratory of Cell Biology, Ministry of Public Health of China, and Key Laboratory of Medical Cell Biology, Ministry of Education of China, China Medical University, Shenyang 110122, People’s Republic of China
3Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China
4Liaoning Research Center for Translational Medicine in Nervous System Disease, Shenyang 110004, People’s Republic of China

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Van Meir, 2010, Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma, CA Cancer J. Clin., 60, 166, 10.3322/caac.20069

Neuwelt, 2008, Strategies to advance translational research into brain barriers, Lancet Neurol., 7, 84, 10.1016/S1474-4422(07)70326-5

Czupalla, 2014, In vitro models of the blood-brain barrier, Methods Mol. Biol., 1135, 415, 10.1007/978-1-4939-0320-7_34

Abbott, 2010, Structure and function of the blood-brain barrier, Neurobiol. Dis., 37, 13, 10.1016/j.nbd.2009.07.030

Gu, 2009, The molecular mechanism of dexamethasone-mediated effect on the blood-brain tumor barrier permeability in a rat brain tumor model, Neurosci. Lett., 452, 114, 10.1016/j.neulet.2008.12.047

Vorbrodt, 2003, Molecular anatomy of intercellular junctions in brain endothelial and epithelial barriers: electron microscopist's view, Brain Res. Brain Res. Rev., 42, 221, 10.1016/S0165-0173(03)00177-2

Yeung, 2008, Decreased junctional adhesion molecule-A expression during blood-brain barrier breakdown, Acta Neuropathol., 115, 635, 10.1007/s00401-008-0364-4

Cai, 2015, The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144, Oncotarget, 6, 19759, 10.18632/oncotarget.4331

Miao, 2015, MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5, Cell. Signal., 27, 156, 10.1016/j.cellsig.2014.10.008

Gutschner, 2012, The hallmarks of cancer: a long non-coding RNA point of view, RNA Biol., 9, 703, 10.4161/rna.20481

Naganuma, 2013, Paraspeckle formation during the biogenesis of long non-coding RNAs, RNA Biol., 10, 456, 10.4161/rna.23547

Chakravarty, 2014, The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer, Nat. Commun., 5, 5383, 10.1038/ncomms6383

Pan, 2015, Upregulation and clinicopathological significance of long non-coding NEAT1 RNA in NSCLC tissues, Asian Pac. J. Cancer Prev., 16, 2851, 10.7314/APJCP.2015.16.7.2851

Kim, 2010, Identification of differentially expressed genes using an annealing control primer system in stage III serous ovarian carcinoma, BMC Cancer, 10, 576, 10.1186/1471-2407-10-576

Li, 2015, NEAT expression is associated with tumor recurrence and unfavorable prognosis in colorectal cancer, Oncotarget, 6, 27641, 10.18632/oncotarget.4737

He, 2016, Aberrant NEAT1 expression is associated with clinical outcome in high grade glioma patients, APMIS, 124, 169, 10.1111/apm.12480

He, 2004, MicroRNAs: small RNAs with a big role in gene regulation, Nat. Rev. Genet., 5, 522, 10.1038/nrg1379

Alvarez-Garcia, 2005, MicroRNA functions in animal development and human disease, Development, 132, 4653, 10.1242/dev.02073

Slaby, 2010, MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients, Neoplasma, 57, 264, 10.4149/neo_2010_03_264

Zhang, 2012, miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression, Neuro-Oncology, 14, 712, 10.1093/neuonc/nos089

Ma, 2014, MiR-181a regulates blood-tumor barrier permeability by targeting Kruppel-like factor 6, J. Cereb. Blood Flow Metab., 34, 1826, 10.1038/jcbfm.2014.152

Sun, 2012, MicroRNA-181b regulates NF-kappaB-mediated vascular inflammation, J. Clin. Invest., 122, 1973

Tominaga, 2015, Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier, Nat. Commun., 6, 6716, 10.1038/ncomms7716

Wang, 2012, MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2, J. Cancer Res. Clin. Oncol., 138, 573, 10.1007/s00432-011-1114-x

Lefebvre, 2010, The SoxD transcription factors–Sox5, Sox6, and Sox13–are key cell fate modulators, Int. J. Biochem. Cell Biol., 42, 429, 10.1016/j.biocel.2009.07.016

Hersh, 2011, SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development, Am. J. Respir. Crit. Care Med., 183, 1482, 10.1164/rccm.201010-1751OC

Ueda, 2007, Preferential expression and frequent IgG responses of a tumor antigen, SOX5, in glioma patients, Int. J. Cancer, 120, 1704, 10.1002/ijc.22472

Yang, 2013, Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice, J. Clin. Invest., 123, 418, 10.1172/JCI64547

Cesana, 2011, A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA, Cell, 147, 358, 10.1016/j.cell.2011.09.028

Xu, 2014, Long non-coding RNAs: new players in ocular neovascularization, Mol. Biol. Rep., 41, 4493, 10.1007/s11033-014-3320-5

Lopez-Pajares, 2015, A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation, Dev. Cell, 32, 693, 10.1016/j.devcel.2015.01.028

Prensner, 2011, The emergence of lncRNAs in cancer biology, Cancer Discov., 1, 391, 10.1158/2159-8290.CD-11-0209

Clemson, 2009, An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles, Mol. Cell, 33, 717, 10.1016/j.molcel.2009.01.026

Choudhry, 2015, Tumor hypoxia induces nuclear paraspeckle formation through HIF-2alpha dependent transcriptional activation of NEAT1 leading to cancer cell survival, Oncogene, 34, 4546, 10.1038/onc.2014.431

You, 2014, MicroRNA-449a inhibits cell growth in lung cancer and regulates long noncoding RNA nuclear enriched abundant transcript 1, Indian J. Cancer, 51, e77, 10.4103/0019-509X.154055

Zhen, 2016, Long noncoding RNA NEAT1 promotes glioma pathogenesis by regulating miR-449b-5p/c-Met axis, Tumour Biol., 37, 673, 10.1007/s13277-015-3843-y

Cai, 2015, Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression, J. Neuropathol. Exp. Neurol., 74, 25, 10.1097/NEN.0000000000000146

Liu, 2014, Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer, Mol. Cancer, 13, 92, 10.1186/1476-4598-13-92

Jalali, 2013, Systematic transcriptome wide analysis of lncRNA-miRNA interactions, PLoS One, 8, 10.1371/journal.pone.0053823

Li, 2015, Genome-scale identification of miRNA-mRNA and miRNA-lncRNA interactions in domestic animals, Anim. Genet., 46, 716, 10.1111/age.12329

Wang, 2015, Long non-coding RNA CASC2 suppresses malignancy in human gliomas by miR-21, Cell. Signal., 27, 275, 10.1016/j.cellsig.2014.11.011

Zhao, 2015, miR-34c regulates the permeability of blood-tumor barrier via MAZ-mediated expression changes of ZO-1, occludin, and claudin-5, J. Cell. Physiol., 230, 716, 10.1002/jcp.24799

Zhao, 2015, MiR-34a regulates blood-tumor barrier function by targeting protein kinase Cepsilon, Mol. Biol. Cell, 26, 1786, 10.1091/mbc.e14-10-1474

Zietara, 2013, Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells, Proc. Natl. Acad. Sci. U. S. A., 110, 7407, 10.1073/pnas.1221984110

Belkaya, 2014, Transgenic expression of microRNA-181d augments the stress-sensitivity of CD4(+)CD8(+) thymocytes, PLoS One, 9, e85274, 10.1371/journal.pone.0085274

Lefebvre, 2007, Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors, Int. J. Biochem. Cell Biol., 39, 2195, 10.1016/j.biocel.2007.05.019

Suto, 2015, Sox5 and Th17 cell differentiation, Oncotarget, 6, 19952, 10.18632/oncotarget.4784

Ma, 2009, DNA fingerprinting tags novel altered chromosomal regions and identifies the involvement of SOX5 in the progression of prostate cancer, Int. J. Cancer, 124, 2323, 10.1002/ijc.24243

Riker, 2008, The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis, BMC Med. Genet., 1, 13

Huang, 2008, Transcription factor SOX-5 enhances nasopharyngeal carcinoma progression by down-regulating SPARC gene expression, J. Pathol., 214, 445, 10.1002/path.2299

Pei, 2014, Sox5 induces epithelial to mesenchymal transition by transactivation of Twist1, Biochem. Biophys. Res. Commun., 446, 322, 10.1016/j.bbrc.2014.02.109