Bioadhesive microdevices with multiple reservoirs: a new platform for oral drug delivery

Saffran, 1990, Biodegradable azopolymer coating for oral delivery of peptide drugs, Biochem. Soc. Trans., 18, 752, 10.1042/bst0180752 Iwanaga, 1999, Application of surface-coated liposomes for oral delivery of peptide: effects of coating the liposome’s surface on the GI transit of insulin, J. Pharm. Sci., 88, 248, 10.1021/js980235x Ponchel, 1998, Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract, Adv. Drug Deliv. Rev., 34, 191, 10.1016/S0169-409X(98)00040-4 Arangoa, 2000, Bioadhesive potential of gliadin nanoparticulate systems, Eur. J. Pharm. Sci., 11, 333, 10.1016/S0928-0987(00)00121-4 Lehr, 2000, Lectin-mediated drug delivery, J. Control. Release, 65, 19, 10.1016/S0168-3659(99)00228-X Fara, 1985, Evaluation of oxprenolol and metoprolol Oros systems in the dog: comparison of in vivo and in vitro drug release, and of drug absorption from duodenal and colonic infusion sites, Br. J. Clin. Pharmacol., 19, 91S, 10.1111/j.1365-2125.1985.tb02748.x Davis, 1988, Relationship between the rate of appearance of oxprenolol in the systemic circulation and the location of an oxprenolol 16/260 drug delivery system within the gastrointestinal tract as determined by scinigraphy, Br. J. Clin. Pharmacol., 26, 435, 10.1111/j.1365-2125.1988.tb03403.x Fasano, 1997, Modulation of intestinal tight junctions by Zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model, J. Clin. Invest., 99, 1158, 10.1172/JCI119271 Fasano, 1998, Innovative strategies for the oral delivery of drugs and peptides, Trends Biotechnol., 16, 152, 10.1016/S0167-7799(97)01170-0 Schwarz, 2000, Int. J. Clin. Pharmacol. Ther., 38, 161, 10.5414/CPP38161 Leoni, 2001, Nanoporous biocapsules for the encapsulation of insulinoma cells: biotransport and biocompatibility considerations, IEEE Trans. Biomed. Eng., 48, 11, 10.1109/10.959329 Santini, 1999, A controlled release microchip, Nature, 397, 335, 10.1038/16898 Irrache, 1996, Bioadhesion of lectin–latex conjugates to rat intestinal mucosa, Pharm. Res., 13, 1716, 10.1023/A:1016405126656 Hussain, 1997, Enhanced oral uptake of tomato-lectin-conjugated nanoparticles in the rat, Pharm. Res., 14, 613, 10.1023/A:1012153011884 Nashat, 1998, Detection of functional groups and antibodies on microfabricated surfaces by confocal microscopy, Biotechnol. Bioeng., 60, 137, 10.1002/(SICI)1097-0290(19981020)60:2<137::AID-BIT1>3.0.CO;2-O Sultzbaugh, 1996, A method to attach lectins to the surface of spermine alginate microcapsules based on avidin biotin interaction, J. Microencapsul., 13, 363, 10.3109/02652049609026023 Gabor, 1998, Lectin-mediated bioadhesion: binding characteristics of plant lectins on the enterocyte-like cell lines Caco-2, HT-29, and HCT-8, J. Control. Release, 55, 131, 10.1016/S0168-3659(98)00043-1 Desai, 1995, Silicon microimplants: fabrication and biocompatibility, 97 Zhang, 1998, Proteins and Cells on PEG Immobilized Silicon Surfaces, Biomaterials, 19, 953, 10.1016/S0142-9612(98)00026-X C. Bonner, S. Tao, T.A. Desai. Fabrication and characterization of PMMA microdevices for drug delivery, (2002) in preparation. Eaimtrakarn, 2001, Retention and transit of intestinal mucoadhesive films in rat small intestine, Int. J. Pharm., 224, 61, 10.1016/S0378-5173(01)00738-4 Sangalli, 2001, In vitro and in vivo evaluation of an oral system for time and/or site-specific drug delivery, J. Control. Release, 73, 103, 10.1016/S0168-3659(01)00291-7