Alginate microparticles prepared by spray–coagulation method: Preparation, drug loading and release characterization

International Journal of Pharmaceutics - Tập 303 Số 1-2 - Trang 171-181 - 2005
Junpin Tu1, Srinivasa Rao Bolla1, John Barr2, Jan‐Pieter Miedema2, X. Li1, Bhaskara Jasti1
1Thomas J Long School of Pharmacy and Health Sciences, University of the Pacific, 751 Brookside Road, Stockton, CA 95211, USA
2AP Pharma. Inc., Redwood City, CA 94063, USA

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Tài liệu tham khảo

Chan, 2002, Cross-linking mechanisms of calcium and zinc in production of alginate microspheres, Int. J. Pharm., 242, 255, 10.1016/S0378-5173(02)00169-2

Chan, 2002, Production of alginate microspheres by internal gelation using an emulsification method, Int. J. Pharm., 242, 259, 10.1016/S0378-5173(02)00170-9

Fundueanu, 1999, Physio-chemical characterization of Ca–alginate microparticles produced with different methods, Biomaterials, 20, 1427, 10.1016/S0142-9612(99)00050-2

Gometz, 1998, Protein release from alginate matrices, Adv. Drug Deliv. Rev., 31, 267, 10.1016/S0169-409X(97)00124-5

Kikuchi, 1997, Pulsed dextran release from calcium–alginate gel beads, J. Control Release, 47, 21, 10.1016/S0168-3659(96)01612-4

Kikuchi, 1999, Effect of Ca2+–alginate gel dissolution on release of dextran with different molecular weights, J. Control Release, 58, 21, 10.1016/S0168-3659(98)00141-2

Kwok, 1991, Production of 5–15mm diameter alginate–polylysine microcapsules by an air-atomization technique, Pharm. Res., 8, 341, 10.1023/A:1015841531372

Mandal, 2001, Porous biodegradable microparticles for delivery of pentamidine, Eur. J. Pharm. Biopharm., 52, 91, 10.1016/S0939-6411(01)00150-3

Martin, 1993

Miyazaki, 1995, Drug release from oral mucosal adhesive tablets of chitosan and sodium alginate, Int. J. Pharm., 118, 257, 10.1016/0378-5173(94)00396-M

Mofidi, 2000, Mass preparation and characterization of alginate microspheres, Process Biochem., 35, 885, 10.1016/S0032-9592(99)00149-1

Poncelet, 2001, Production of alginate beads by emulsification/internal gelation, Ann. N.Y. Acad. Sci., 944, 74, 10.1111/j.1749-6632.2001.tb03824.x

Shu, 2002, The release behavior of brilliant blue from calcium–alginate gel beads coated by chitosan: the preparation method effect, Eur. J. Pharm. Biopharm., 53, 193, 10.1016/S0939-6411(01)00247-8

Tonnesen, 2002, Alginate in drug delivery systems, Drug Dev. Ind. Pharm., 28, 621, 10.1081/DDC-120003853

Vauthier, 2000

You, 2001, Preparation of regular sized Ca–alginate microspheres using memethylene bluerane emulsification method, J. Microencapsul., 18, 521, 10.1080/02652040010018128