Induction of a Th17 cell response by Helicobacter pylori Urease subunit B

Akhiani, 2002, Protection against Helicobacter pylori infection following immunization is IL-12-dependent and mediated by Th1 cells, J. Immunol., 169, 6977, 10.4049/jimmunol.169.12.6977 Andersen, 2007, Colonization and infection by Helicobacter pylori in humans, Helicobacter, 12, 12, 10.1111/j.1523-5378.2007.00574.x Andrutis, 1995, Inability of an isogenic urease-negative mutant stain of Helicobacter mustelae to colonize the ferret stomach, Infect. Immun., 63, 3722, 10.1128/IAI.63.9.3722-3725.1995 Bamford, 1998, Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype, Gastroenterology, 114, 482, 10.1016/S0016-5085(98)70531-1 Bettelli, 2006, Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells, Nature, 441, 235, 10.1038/nature04753 Caruso, 2008, IL-23-mediated regulation of IL-17 production in Helicobacter pylori-infected gastric mucosa, Eur. J. Immunol., 38, 470, 10.1002/eji.200737635 DeLyria, 2009, Vaccination of mice against H. pylori induces a strong Th-17 response and immunity that is neutrophil dependent, Gastroenterology, 136, 247, 10.1053/j.gastro.2008.09.017 Dong, 2008, TH17 cells in development: an updated view of their molecular identity and genetic programming, Nat. Rev. Immunol., 8, 337, 10.1038/nri2295 Eaton, 2001, The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice, J. Immunol., 166, 7456, 10.4049/jimmunol.166.12.7456 Ermak, 1998, Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responses, J. Exp. Med., 188, 2277, 10.1084/jem.188.12.2277 Harrington, 2005, Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages, Nat. Immunol., 6, 1123, 10.1038/ni1254 Harris, 1996, Helicobacter pylori urease is a potent stimulus of mononuclear phagocyte activation and inflammatory cytokine production, Gastroenterology, 111, 419, 10.1053/gast.1996.v111.pm8690207 Ikeda, 2007, Aggregated ursolic acid, a natural triterpenoid, induces IL-1beta release from murine peritoneal macrophages: role of CD36, J. Immunol., 178, 4854, 10.4049/jimmunol.178.8.4854 Kusters, 2006, Pathogenesis of Helicobacter pylori infection, Clin. Microbiol. Rev., 19, 449, 10.1128/CMR.00054-05 Li, 2006, Cholesterol-induced apoptotic macrophages elicit an inflammatory response in phagocytes, which is partially attenuated by the Mer receptor, J. Biol. Chem., 281, 6707, 10.1074/jbc.M510579200 Li, 2005, Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis, J. Biol. Chem., 280, 21763, 10.1074/jbc.M501759200 Lu, 2003, Recombinant Helicobacter pylori urease B subunit and its biological properties, Di Yi Jun Yi Da Xue Xue Bao, 23, 549 Lundgren, 2005, Helicobacter pylori-specific CD4+ T cells home to and accumulate in the human Helicobacter pylori-infected gastric mucosa, Infect. Immun., 73, 5612, 10.1128/IAI.73.9.5612-5619.2005 Luzza, 2000, Up-regulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa, J. Immunol., 165, 5332, 10.4049/jimmunol.165.9.5332 Mikula, 2003, Quantitative detection for low levels of Helicobacter pylori infection in experimentally infected mice by real-time PCR, J. Microbiol. Methods, 55, 351, 10.1016/S0167-7012(03)00166-0 Mizuno, 2005, Interleukin-17 levels in Helicobacter pylori-infected gastric mucosa and pathologic sequelae of colonization, World J. Gastroenterol., 11, 6305, 10.3748/wjg.v11.i40.6305 Mohammadi, 1996, Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotype and promote a delayed-type hypersensitivity response in the stomachs of mice, J. Immunol., 156, 4729, 10.4049/jimmunol.156.12.4729 Mus, 2010, IL-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for IL-22 but not IL-21 in autoimmune experimental arthritis, Arthritis Rheum., 62, 1043, 10.1002/art.27336 Novak, 1999, Poliovirus replicons encoding the B subunit of Helicobacter pylori urease elicit a Th1 associated immune response, Vaccine, 17, 2384, 10.1016/S0264-410X(99)00035-3 Pappo, 1999, Helicobacter pylori infection in immunized mice lacking major histocompatibility complex class I and class II functions, Infect. Immun., 67, 337, 10.1128/IAI.67.1.337-341.1999 Roussel, 2005, Evaluation of DNA extraction methods from mouse stomachs for the quantification of H. pylori by real-time PCR, J. Microbiol. Methods, 62, 71, 10.1016/j.mimet.2005.01.011 Shi, 2010, Helicobacter pylori-induced Th17 responses modulate Th1 cell responses, benefit bacterial growth, and contribute to pathology in mice, J. Immunol., 184, 5121, 10.4049/jimmunol.0901115 Smythies, 2005, Poliovirus replicons encoding the B subunit of Helicobacter pylori urease protect mice against H. pylori infection, Vaccine, 23, 901, 10.1016/j.vaccine.2004.07.037 Smythies, 2000, Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-gamma, gene-deficient mice, J. Immunol., 165, 1022, 10.4049/jimmunol.165.2.1022 Tan, 2004, Motility of urease-deficient derivatives of Helicobacter pylori, J. Bacteriol., 186, 885, 10.1128/JB.186.3.885-888.2004 Tsuda, 1994, A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach, Infect. Immun., 62, 3586, 10.1128/IAI.62.8.3586-3589.1994 Velin, 2009, Interleukin-17 is a critical mediator of vaccine-induced reduction of Helicobacter infection in the mouse model, Gastroenterology, 136, 2237, 10.1053/j.gastro.2009.02.077 Wu, 2005, Preparation of anti-Helicobacter pylori UreB monoclonal antibody and the detection of the ability of inhibition the urease activity, Immunol. J., 21, 393 Yang, 2005, Oral immunization of mice with vaccine of attenuated Salmonella typhimurium expressing Helicobacter pylori urease B subunit, Biomed. Environ. Sci., 18, 411