Synthesis of peptidomimetic-spirostane hybrids via Ugi reaction: a versatile approach for the formation of peptide–steroid conjugates

Hostettman, 1995 Mbadugha, 2003, Org. Lett., 5, 4041, 10.1021/ol030084r Cheng, 1992, J. Am. Chem. Soc., 114, 7319, 10.1021/ja00044a067 Boyce, 1994, J. Am. Chem. Soc., 116, 7955, 10.1021/ja00096a086 Cheng, 1996, J. Am. Chem. Soc., 118, 1813, 10.1021/ja952976v Madder, 2002, J. Comb. Chem., 4, 552, 10.1021/cc020016g De Muynck, 2000, Angew. Chem., Int. Ed., 39, 145, 10.1002/(SICI)1521-3773(20000103)39:1<145::AID-ANIE145>3.0.CO;2-J Ding, 2004, Org. Lett., 6, 3433, 10.1021/ol048845t Adamczyk, 2000, Steroids, 65, 387, 10.1016/S0039-128X(00)00095-7 Adamczyk, 1999, Steroids, 64, 283, 10.1016/S0039-128X(99)00004-5 Muddana, 2004, Org. Lett., 6, 1409, 10.1021/ol0497537 Dömling, 2006, Chem. Rev., 106, 17, 10.1021/cr0505728 Ugi, 2003, Molecules, 8, 53, 10.3390/80100053 Dömling, 2000, Angew. Chem., Int. Ed., 39, 3168, 10.1002/1521-3773(20000915)39:18<3168::AID-ANIE3168>3.0.CO;2-U Hulme, 2005, 311 Weber, 2002, Curr. Med. Chem., 9, 1241, 10.2174/0929867023368719 Weber, 2002, Drug Discovery Today, 7, 143, 10.1016/S1359-6446(01)02090-6 Patch, 2003, J. Am. Chem. Soc., 125, 12092, 10.1021/ja037320d Patch, 2002, Curr. Opin. Chem. Biol., 6, 872, 10.1016/S1367-5931(02)00385-X Barron, 1999, Curr. Opin. Chem. Biol., 3, 681, 10.1016/S1367-5931(99)00026-5 Miller, 1995, Drug. Dev. Res., 35, 20, 10.1002/ddr.430350105 Wessjohann, 2005, Angew. Chem., Int. Ed., 44, 4785, 10.1002/anie.200500019 Rivera, 2006, Steroids, 71, 1, 10.1016/j.steroids.2005.02.024 Rodríguez, 2003, J. Braz. Chem. Soc., 14, 466, 10.1590/S0103-50532003000300022 Iglesias-Arteaga, 2002, Steroids, 67, 159, 10.1016/S0039-128X(01)00150-7 Iglesias-Arteaga, 2001, J. Chem. Soc., Perkin Trans. 1, 3, 261, 10.1039/b007656m Lee, 2002, Org. Lett., 4, 313, 10.1021/ol0165894 Betancor, 2002, Org. Lett., 4, 1295, 10.1021/ol025580e Lee, 2003, Org. Lett., 5, 2247, 10.1021/ol034551g Li, 2003, Org. Lett., 5, 2849, 10.1021/ol034894e Pettit, 1998, J. Nat. Prod., 61, 955, 10.1021/np9800405 Fukuzawa, 1997, J. Org. Chem., 62, 4484, 10.1021/jo970091r