Phthalate metabolites in urine of CF patients are associated with use of enteric-coated pancreatic enzymes

Centers for Disease Control Prevention, 2005 Dominguez-Munoz, 2007, Pancreatic enzyme therapy for pancreatic exocrine insufficiency, Curr. Gastroenterol. Rep., 9, 116, 10.1007/s11894-007-0005-4 Ferrone, 2007, Pancreatic enzyme pharmacotherapy, Pharmacotherapy, 27, 910, 10.1592/phco.27.6.910 Frederikson, 2007, Metabolites of phthalates in humans, Mol. Nutr. Food Res., 51, 899, 10.1002/mnfr.200600243 Hauser, 2004, Medications as a source of human exposure to phthalates, Environ. Health Perspect., 112, 751, 10.1289/ehp.6804 Hultcrantz, 1986, Morphological findings in the liver of children with cystic fibrosis: a light and electron microscopy study, Hepatology, 6, 881, 10.1002/hep.1840060513 Innis, 2008, Cystic fibrosis and nutrition: linking phospholipids and essential fatty acids with thiol metabolism, Annu. Rev. Nutr., 28, 55, 10.1146/annurev.nutr.27.061406.093625 Innis, 2007, Choline related supplements improve abnormal plasma methionine-homocysteine metabolites and glutathione status in children with cystic fibrosis, Am. J. Clin. Nutr., 85, 702, 10.1093/ajcn/85.3.702 Innis, 2006, Evidence of choline depletion with reduced betaine and dimethylglycine with increased homocysteine in children with cystic fibrosis, J. Nutr., 136, 2226, 10.1093/jn/136.8.2226 Innis, 2003, Increased plasma homocysteine and S-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis, J. Pediatr., 143, 351, 10.1067/S0022-3476(03)00326-3 Mapuskar, 2007, Dose-dependent sub-chronic toxicity of diethylphthalate in female Swiss mice, Pest. Biochem. Physiol., 87, 156, 10.1016/j.pestbp.2006.07.005 Pereira, 2006, Chronic toxicity of diethyl phthalate in male Wistar rats – a dose–response study, Regul. Toxicol. Pharmacol., 45, 169, 10.1016/j.yrtph.2006.04.006 Pereira, 2007, Chronic toxicity of diethyl phthalate. A 3 generation lactational and gestational exposure study on male Wistar rats, Environ. Toxicol. Pharmacol., 23, 319, 10.1016/j.etap.2006.12.005 Rosenfeld, 2000, Early pulmonary infection, inflammation and clinical outcomes in infants with cystic fibrosis, Pediatr. Pulmomol., 32, 356, 10.1002/ppul.1144 Roum, 1993, Systemic deficiency of glutathione in cystic fibrosis, J. Appl. Physiol., 75, 2419, 10.1152/jappl.1993.75.6.2419 Sathyanarayana, 2008, Phthalates and children's health, Curr. Probl. Pediatr. Adolesc. Health Care, 38, 34, 10.1016/j.cppeds.2007.11.001 Shea, 2003, Pediatric exposure and potential toxicity of phthalate plasticizers, Pediatrics, 111, 1467, 10.1542/peds.111.6.1467 Silva, 2007, Metabolite profiles of di-n-butyl phthalate in humans and rats, Environ. Sci. Technol., 41, 7576, 10.1021/es071142x Wolff, 2007, Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls, Environ. Health Perspect., 115, 116, 10.1289/ehp.9488