Physiologic pharmacokinetic models and interanimal species scaling

Pharmacology & Therapeutics - Tập 29 - Trang 49-68 - 1985
Malcolm Rowland1
1Department of Pharmacy, University of Manchester, Manchester M13 9PL U.K.

Tài liệu tham khảo

Ahmad, 1983, Models of hepatic drug clearance: Discrimination between the “well-stirred” and “parallel-tube” models, J. pharm. Pharmac., 35, 219, 10.1111/j.2042-7158.1983.tb02916.x Ahmad, 1984, Influence of route of hepatic administration on drug availability, J. Pharmac. exp. Ther., 230, 118 Andersen, 1981, A physiologically based toxicokinetic description of the metabolism of inhaled gases and vapours: Analysis at steady state, Toxic. appl. Pharmac., 60, 509, 10.1016/0041-008X(81)90338-0 Anderson, 1982, Recent advances in methodology and concepts for characterising inhalation pharmacokinetic parameters in animals and man, Drug Met. Rev., 13, 791 Bass, 1978, Hepatic elimination of flowing substances: the distributed model, J. theor. Biol., 72, 161, 10.1016/0022-5193(78)90023-1 Bassingthwaighte, 1970, Blood flow and diffusion through mammalian organs, Science, 167, 1347, 10.1126/science.167.3923.1347 Bechtold, 1983, Cyclic interconversion of vitamin K1 and vitamin K1, 2,3-epoxide in man, Br. J. clin. Pharmac., 16, 683, 10.1111/j.1365-2125.1983.tb02241.x Benowitz, 1974, Lidocaine disposition kinetics in monkey and man. I. Prediction by a perfusion model, Clin. Pharmac. Ther., 16, 87, 10.1002/cpt1974161part187 Benowitz, 1974, Lidocaine disposition kinetics in monkey and man. II. Effects of haemorrhage and sympathominetic drug administration, Clin. Pharmac. Ther., 16, 99, 10.1002/cpt1974161part199 Bischoff, 1968, Thiopental pharmacokinetics, J. pharm. Sci., 57, 1346, 10.1002/jps.2600570814 Bischoff, 1970, Preliminary model of methotrexate pharmacokinetics, J. pharm. Sci., 59, 149, 10.1002/jps.2600590203 Bischoff, 1971, Methotrexate pharmacokinetics, J. pharm. Sci., 60, 1128, 10.1002/jps.2600600803 Boxenbaum, 1980, Interspecies variation in liver weight, hepatic blood flow and antipyrine iintrinsic clearance: extrapolation of data to benzodiazapines and phenytoin, J. Pharmacokin. Biopharm., 8, 165, 10.1007/BF01065191 Boxenbaum, 1982, Literature growth in pharmacokinetics, J. Pharmacokin. Biopharm., 10, 335, 10.1007/BF01059265 Boxenbaum, 1982, Interspecies scaling, allometry, physiological time and the ground plan of pharmacokinetics, J. Pharmacokin. Biopharm., 10, 201, 10.1007/BF01062336 Boxenbaum, 1982, Comparative pharmacokinetics of benzodiazepines in dog and man, J. Pharmacokin. Biopharm., 10, 411, 10.1007/BF01065172 Boxenbaum, 1984, Interspecies pharmcokinetic scaling and the evolutionary-comparative paradigm, Drug Metab. Rev., 10.3109/03602538409033558 Boxenbaum, 1983, Interspecies scaling and the pharmacokinetic space-time continuum: Ergosomes, apolysichrons, pharmacokinetic stuff and the Dedrick plots, Am. J. Physiol., 245, R768 Brodie, 1960, The importance of dissociation and lipid solubility in influencing the passage of drugs in the cerebrospinal fluid, J. Pharmac. exp. Ther., 130, 20 Bungay, 1976, Pharmacokinetic modelling of the dogfish shark (squalas acanthia). Distribution and urinary and biliary excretion of phenol red and its glucuronide, J. Pharmacokin. Biopharm., 4, 377, 10.1007/BF01062827 Chen, 1978, Pharmacokinetic model for salicylates in the cerebrospinal fluid, blood, organs and tissues, J. pharm. Sci., 67, 38, 10.1002/jps.2600670111 Chen, 1979, Estimation of tissue-to-plasma partition coefficients used in physiological pharmacokinetic models, J. Pharmacokin. Biopharm., 7, 117, 10.1007/BF01059446 Chen, 1982, Arterial and venous blood sampling in pharmacokinetic studies: Griseofulvin, J. pharm. Sci., 71, 1386, 10.1002/jps.2600711219 Cutler, 1978, Linear systems analysis in pharmacokinetics, J. Pharmacokin. Biopharm., 6, 265, 10.1007/BF01312266 Cutler, 1979, A linear recirculation model of drug disposition, J. Pharmacokin. Biopharm., 7, 101, 10.1007/BF01059445 Cutler, 1981, Properties of the recirculating model: Calculation of amount of drug in the body from blood concentration data with application to absorption rate calculations, J. Pharmacokin. Biopharm., 9, 225, 10.1007/BF01068084 Dedrick, 1974, Animal scale-up, 117 Dedrick, 1970, Interspecies correlation of plasma concentration history of methotrexate (NSC-740), Cancer Chemother. Rep., 54, 95 Dedrick, 1973, Pharmacokinetics of 1-β-D-arabino-furanosylcytosine (ARA-C) deamination in several species, Biochem. Pharmac., 22, 2405, 10.1016/0006-2952(73)90342-0 Dedrick, 1972, In vitro-in vivo correlation of drug metabolism—deamination of 1-D-arabinofuranosylcytosine, Biochem. Pharmac., 21, 1, 10.1016/0006-2952(72)90245-6 Dedrick, 1973, Transport and binding of methotrexate in vivo, J. pharm. Sci., 62, 882, 10.1002/jps.2600620603 Fleuren, 1979, Dose-dependent urinary excretion of chlorthalidone, Clin. Pharmac. Ther., 25, 806, 10.1002/cpt1979256806 Forker, 1978, Hepatic transport kinetics and plasma disappearance curves: distributed modelling versus conventional approach, Am. J. Physiol., 235, E648 Forker, 1981, Albumin helps mediate removal of taurocholate by rat liver, J. clin. Invest., 67, 1517, 10.1172/JCI110182 Gabrielsson, 1983, A physiological pharmacokinetic model for morphine disposition in the pregnant rat, J. Pharmacokin. Biopharm., 11, 147, 10.1007/BF01061846 Gambertoglio, 1980, Pharmacokinetics and bioavailability of prednisone and prednisolone in healthy volunteers and patients: A review, J. Pharmacokin. Biopharm., 8, 1, 10.1007/BF01059447 Gibaldi, 1971, Influence of first-pass effect on availability of drugs on oral administration, J. pharm. Sci., 60, 1338, 10.1002/jps.2600600909 Goresky, 1963, A linear method for determining liver sinusoidal and extravascular volume, Am. J. Physiol., 204, 626, 10.1152/ajplegacy.1963.204.4.626 Greene, 1978, Physiological perfusion model for cephalosporin antibiotics. I: Model selection based on blood drug concentrations, J. pharm. Sci., 67, 191, 10.1002/jps.2600670217 Greenway, 1971, Hepatic vascular beds, Physiol. Rev., 51, 23, 10.1152/physrev.1971.51.1.23 Guentert, 1980, Effect of plasma protein binding on quinidine kinetics in the rabbit, J. Pharmac. exp. Ther., 215, 165 Hall, 1983, Relationship between renal clearance, protein binding and urine flow for digitoxin, a compound of low clearance in the isolated perfused rat kidney, J. Pharmac. exp. Ther., 227, 174 Harris, 1975, Preliminary pharmacokinetic model for adriamycin, Cancer Chemother. Rep., 54, 819 Harrison, 1977, Physiologically based pharmacokinetic model for digoxin distribution and elimination in the rat, J. pharm. Sci., 66, 1138, 10.1002/jps.2600660822 Hekman, 1982, Kinetic modelling of the renal excretion of iodopyracet in the dog, J. Pharmacokin. Biopharm., 10, 77, 10.1007/BF01059184 Himmelstein, 1977, Mathematical model for cyclocytidine pharmacokinetics, J. pharm. Sci., 66, 1441, 10.1002/jps.2600661024 Himmelstein, 1979, A review of the applications of physiologically based pharmacokinetic modelling, J. Pharmacokin. Biopharm., 7, 127, 10.1007/BF01059734 Igari, 1982, Comparative physiologically based pharmacokinetics of hexobarbital, phenobarbital and thiopental in the rat, J. Pharmacokin. Biopharm., 10, 53, 10.1007/BF01059183 Igari, 1983, Prediction of diazepam disposition in the rat and man by a physiologically based pharmacokinetic model, J. Pharmacokin. Biopharm., 11, 577, 10.1007/BF01059058 Jansen, 1981, Influence of plasma protein binding kinetics on hepatic clearance assessed from a “tube” model and a “well-stirred” model, J. Pharmacokin. Biopharm., 9, 15, 10.1007/BF01059340 Jones, 1984, Discrimination between the venous equilibrium and sinusoidal models of hepatic drug elimination in the isolated perfused rat liver by perturbation of propranolol protein binding, J. Pharmac. exp. Ther., 229, 522 Kamiya, 1983, Quantitative investigation of renal handling of drugs in rabbits, dogs and humans, J. pharm. Sci., 72, 440, 10.1002/jps.2600720429 Kardon, 1980, Three-dimensional organisation of the hepatic microcirculation in the rodent as observed by scanning electronmicroscopy of corrosion casts, Gastroenterology, 79, 72, 10.1016/0016-5085(80)90077-3 Keiding, 1979, Hepatic clearance measurements and pharmacokinetics, Pharmacology, 19, 105, 10.1159/000137296 Keiding, 1978, Effect of sinusoidal perfusion on galactose elimination kinetics in perfused rat liver, J. Pharmac. exp. Ther., 205, 465 Keiding, 1984, Flow dependence of propranolol elimination in the perfused rat liver, J. Pharmac. exp. Ther., 230, 474 Keiding, 1976, Michealis-Menten kinetics of galactose elimination by the isolated perfused pig liver, Am. J. Physiol., 230, 1302, 10.1152/ajplegacy.1976.230.5.1302 Kety, 1951, The theory and application of inert gases at the lungs and tissues, Pharmac. Rev., 3, 1 Kill, 1961, Dynamics of renal proximal tubular secretion, Nature, 189, 927, 10.1038/189927a0 Levy, 1980, Effect of plasma protein binding on the renal clearance of drugs, J. pharm. Sci., 69, 482, 10.1002/jps.2600690437 Lin, 1982, Physiological pharmacokinetics of ethoxybenzamide based on biochemical data obtained in vitro as well as on physiological data, J. Pharmacokin. Biopharm., 10, 649, 10.1007/BF01062546 Lutz, 1977, A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat, Drug Metab. Disp., 5, 386 Lutz, 1975, The kinetics of methotrexate distribution in spontaneous canine lymphosarcoma, J. Pharmacokin. Biopharm., 3, 77, 10.1007/BF01066017 Lutz, 1977, A model for the kinetics of distribution of actinomycin-D in the beagle dog, J. Pharmac. exp. Ther., 200, 469 Mannervik, 1981, Design and analysis of kinetic experiments for distrimination between rival models, 235 Montandon, 1975, Computer simulation of sulfobromophthalein kinetics in the rat using flow-limited models with extrapolation to man, J. Pharmacokin. Biopharm., 3, 277, 10.1007/BF01066923 Nau, 1981, A new model for embryotoxicity testing: teratogenicity and pharmacokinetics of valproic acid following constant-rate administration in the mouse using human therapeutic drug and metabolite concentrations, Life Sci., 29, 2803, 10.1016/0024-3205(81)90541-5 Ockner, 1983, Hepatic uptake of albumin bound substances: albumin receptor concepts, Am. J. Physiol., 245, G13 Øie, 1980, Effect of saturable binding on the pharmacokinetics of drugs: a simulation, J. pharm. Pharmac., 32, 471, 10.1111/j.2042-7158.1980.tb12971.x Pang, 1977, Hepatic clearance of drugs. I. Theoretical considerations of a “well-stirred” and a “parallel tube” model. Influence of hepatic blood, plasma and blood binding and hepatocellular enzyme activity on hepatic drug clearance, J. Pharmacokin. Biopharm., 5, 625, 10.1007/BF01059688 Pang, 1977, Hepatic clearance of drugs. II. Experimental evidence of acceptance of the “well-stirred” model over the “parallel tube” model using lidocaine in the perfused rat liver in situ preparation, J. Pharmacokin. Biopharm., 5, 655, 10.1007/BF01059689 Pang, 1982, Retrograde perfusion to probe the heterogenous distribution of hepatic drug metabolising enzymes in rats, J. Pharmac. exp. Ther., 216, 339 Papper, 1963, Uptake and Distribution of Anesthetic Agents, 20 Papper, 1963, Uptake and Distribution of Anesthetic Agents, 123 Papper, 1963, Uptake and Distribution of Anesthetic Agents, 134 Perl, 1968, A convection-diffusion model of indicator transport through an organ, Circulation Res., 22, 273, 10.1161/01.RES.22.2.273 Pond, 1984, First pass elimination: Basic concepts and clinical consequences, Clin. Pharmacokin., 9, 1, 10.2165/00003088-198409010-00001 Price, 1960, Uptake of thiopental by body tissues and its relation to the duration of narcosis, Clin. Pharmac. Ther., 1, 16, 10.1002/cpt19601116 Van Rossum, 1983, Dose dependent kinetics, Pharmac. Ther., 21, 77, 10.1016/0163-7258(83)90068-2 Roberts, 1985, Hepatic elimination: Dispersion model, J. pharm. Sci., 74, 585, 10.1002/jps.2600740522 Rowland, 1972, Influence of route of administration on drug availability, J. pharm. Sci., 61, 70, 10.1002/jps.2600610111 Rowland, 1980, Clinical Pharmacokinetics: Concepts and Applications, 287 Rowland, 1973, Clearance concept in pharmacokinetics, J. Pharmacokin. Biopharm., 1, 123, 10.1007/BF01059626 Rowland, 1984, Protein binding and hepatic clearance: discrimination between models of hepatic clearance with diazepam, a drug of high intrinsic clearance, in the isolated perfused rat liver preparation, J. Pharmacokin. Biopharm., 12, 129, 10.1007/BF01059274 Schary, 1983, Protein binding and hepatic clearance: studies with tolbutamide, a drug of low intrinsic clearance, in the isolated perfused rat liver preparation, J. Pharmacokin. Biopharm., 11, 225, 10.1007/BF01061866 Segre, 1982, Compartmental representation, Pharmac. Ther., 17, 111, 10.1016/0163-7258(82)90049-3 Shand, 1975, Effects of route of administration and blood flow on hepatic elimination, J. Pharmac. exp. Ther., 195, 424 Tang-Liu, 1983, Dependence of renal clearance on urine flow—a mathematical model and its applications, J. pharm. Sci., 72, 154, 10.1002/jps.2600720215 Teorell, 1937, Kinetics of distribution of substances administered to the body. I. The extravascular modes of administration, Archs int. Pharmacodyn., 57, 205 Teorell, 1937, Kinetics of distribution of substances administered to the body. II. The intravascular modes of administration, Archs int. Pharmacodyn., 57, 226 Tozer, 1981, Concepts basic to pharmacokinetics, Pharmac. Ther., 12, 109, 10.1016/0163-7258(81)90077-2 Tterlikkis, 1977, Pharmacokinetics of mecaptopurine, J. pharm. Sci., 66, 1454, 10.1002/jps.2600661027 Tucker, 1981, Empirical vs compartmental vs physiological models, 33 Weiner, 1971, Excretion of drugs by the kidney Weiss, 1984, Definition of pharmacokinetic parameters: Influence of sampling site, J. Pharmacokin. Biopharm., 12, 167, 10.1007/BF01059276 Weiss, 1977, Dependence of pharmacokinetic parameters on the body weight, Int. J. clin. Pharmac., 15, 572 Wesson, 1954, A theoretical analysis of urea excretion by the mammalian kidney, Am. J. Physiol., 179, 364, 10.1152/ajplegacy.1954.179.2.364 Wilkinson, 1975, Commentary. A physiological approach to hepatic drug clearance, Clin. Pharmac. Ther., 18, 377, 10.1002/cpt1975184377 Winkler, 1974, The effect of hepatic perfusion on assessment of kinetic constants, 797