Rare Germline Pathogenic Mutations of DNA Repair Genes Are Most Strongly Associated with Grade Group 5 Prostate Cancer

European urology oncology - Tập 3 - Trang 224-230 - 2020
Yishuo Wu1,2, Hongjie Yu1, Shuwei Li3, Kathleen Wiley4, S. Lilly Zheng1, Holly LaDuca3, Marta Gielzak4, Rong Na1, Brice A.J. Sarver3, Brian T. Helfand1, Patrick C. Walsh4, Tamara L. Lotan5,6, Kathleen A. Cooney7, Mary Helen Black3, Jianfeng Xu1,2, William B. Isaacs4,6
1Program for Personalized Cancer Care and Department of Surgery, NorthShore University HealthSystem, Evanston, IL, USA
2Fudan Institute of Urology, Huashan Hospital, Fudan University, Shanghai, China
3Ambry Genetics, Aliso Viejo, CA, USA
4Department of Urology and the James Buchanan Brady Urologic Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD USA.
6Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA
7Duke University School of Medicine and Duke Cancer Institute, Durham, NC, USA

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