CSF biomarkers for Alzheimer's disease: current utility and potential future use

Neurobiology of Aging - Tập 32 - Trang S4-S9 - 2011
David M. Holtzman1
1Department of Neurology, Developmental Biology, Knight Alzheimer's Disease Research Center, and the Hope Center for Neurological Disorders, Washington University, St. Louis, MO, USA

Tài liệu tham khảo

Arai, 2000, CSF phosphorylated tau protein and mild cognitive impairment: a prospective study, Exp. Neurol, 166, 201, 10.1006/exnr.2000.7501 Arai, 1997, Cerebrospinal fluid tau levels in neurodegenerative diseases with distinct tau-related pathology, Biochem. Biophys. Res. Commun, 236, 262, 10.1006/bbrc.1997.6908 Blennow, 2004, CSF biomarkers for mild cognitive impairment, J. Intern. Med, 256, 224, 10.1111/j.1365-2796.2004.01368.x Blennow, 2001, CSF total tau, Abeta42 and phosphorylated tau protein as biomarkers for Alzheimer's disease, Mol. Neurobiol, 24, 87, 10.1385/MN:24:1-3:087 Buée, 2000, Tau protein isoforms, phosphorylation and role in neurodegenerative disorders, Brain Res. Brain Res. Rev, 33, 95, 10.1016/S0165-0173(00)00019-9 Buerger, 2002, Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine, Arch. Neurol, 231, 59, 1267, 10.1001/archneur.59.8.1267 Cairns, 2009, Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report, Arch. Neurol, 66, 1557, 10.1001/archneurol.2009.279 2000 Craig-Schapiro, 2010, YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease, Biol Psychiatry, 68, 903, 10.1016/j.biopsych.2010.08.025 Crystal, 1988, Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease, Neurology, 38, 1682, 10.1212/WNL.38.11.1682 de Leon, 2007, Imaging and CSF studies in the preclinical diagnosis of Alzheimer's disease, Ann. N. Y. Acad. Sci, 1097, 114, 10.1196/annals.1379.012 Fagan, 2006, Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans, Ann. Neurol, 59, 512, 10.1002/ana.20730 Fagan, 2009, Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease, EMBO Mol. Med, 1, 371, 10.1002/emmm.200900048 Fagan, 2007, Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults, Arch. Neurol, 64, 343, 10.1001/archneur.64.3.noc60123 Gustafson, 2007, Cerebrospinal fluid beta-amyloid 1–42 concentration may predict cognitive decline in older women, J. Neurol. Neurosurg. Psychiatry, 78, 461, 10.1136/jnnp.2006.100529 Hampel, 2004, Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study, Arch. Gen. Psychiatry, 61, 95, 10.1001/archpsyc.61.1.95 Hansson, 2006, Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study, Lancet Neurol, 5, 228, 10.1016/S1474-4422(06)70355-6 Hardy, 2002, The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics, Science, 297, 353, 10.1126/science.1072994 Hesse, 2001, Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke, Neurosci. Lett, 297, 187, 10.1016/S0304-3940(00)01697-9 Hu, 2002, Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay, Am. J. Pathol, 160, 1269, 10.1016/S0002-9440(10)62554-0 Jagust, 2009, Relationships between biomarkers in aging and dementia, Neurology, 73, 1193, 10.1212/WNL.0b013e3181bc010c Li, 2007, CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study, Neurology, 69, 631, 10.1212/01.wnl.0000267428.62582.aa Mattsson, 2009, CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment, JAMA, 302, 385, 10.1001/jama.2009.1064 Morris, 1993, The Clinical Dementia Rating (CDR): current version and scoring rules, Neurology, 43, 2412, 10.1212/WNL.43.11.2412-a Motter, 1995, Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease, Ann. Neurol, 38, 643, 10.1002/ana.410380413 Petersen, 1999, Mild cognitive impairment: clinical characterization and outcome, Arch. Neurol, 56, 303, 10.1001/archneur.56.3.303 Portelius, 2008, Characterization of tau in cerebrospinal fluid using mass spectrometry, J. Proteome Res, 7, 2114, 10.1021/pr7008669 Riemenschneider, 2002, Cerebrospinal fluid tau and beta-amyloid 42 proteins identify Alzheimer disease in subjects with mild cognitive impairment, Arch. Neurol, 59, 1729, 10.1001/archneur.59.11.1729 Rowe, 2007, Imaging beta-amyloid burden in aging and dementia, Neurology, 68, 1718, 10.1212/01.wnl.0000261919.22630.ea Shaw, 2009, Cerebrospinal fluid biomarker signature in Alzheimer's Disease Neuroimaging Initiative subjects, Ann. Neurol, 65, 403, 10.1002/ana.21610 Shoji, 1998, Combination assay of CSF tau, A beta 1–40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease, J. Neurol. Sci, 158, 134, 10.1016/S0022-510X(98)00122-1 Skoog, 2003, Cerebrospinal fluid beta-amyloid 42 is reduced before the onset of sporadic dementia: a population-based study in 85-year-olds, Dement. Geriatr. Cogn. Disord, 15, 169, 10.1159/000068478 Snider, 2009, Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer type, Arch. Neurol, 66, 638, 10.1001/archneurol.2009.55 Stomrud, 2007, Cerebrospinal fluid biomarkers predict decline in subjective cognitive function over 3 years in healthy elderly, Dement. Geriatr. Cogn. Disord, 24, 118, 10.1159/000105017 Sunderland, 2003, Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease, JAMA, 289, 2094, 10.1001/jama.289.16.2094 Sunderland, 1999, Longitudinal stability of CSF tau levels in Alzheimer patients, Biol. Psychiatry, 46, 750, 10.1016/S0006-3223(99)00143-2 Tapiola, 2009, Cerebrospinal fluid {beta}amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain, Arch. Neurol, 66, 382, 10.1001/archneurol.2008.596 Verbeek, 2009, Cerebrospinal fluid amyloid beta(40) is decreased in cerebral amyloid angiopathy, Ann. Neurol, 66, 245, 10.1002/ana.21694 Welge, 2009, Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease, J. Neural Transm, 116, 203, 10.1007/s00702-008-0177-6