Signaling by Extracellular Vesicles Advances Cancer Hallmarks

Trends in Cancer - Tập 2 - Trang 84-94 - 2016
Masamitsu Kanada1, Michael H. Bachmann1, Christopher H. Contag1,2,3
1Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 USA
2Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
3Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA

Tài liệu tham khảo

Raposo, 2013, Extracellular vesicles: exosomes, microvesicles, and friends, J. Cell Biol., 200, 373, 10.1083/jcb.201211138 EL Andaloussi, 2013, Extracellular vesicles: biology and emerging therapeutic opportunities, Nat. Rev. Drug Discov., 12, 347, 10.1038/nrd3978 Barteneva, 2013, Circulating microparticles: square the circle, BMC Cell Biol., 14, 23, 10.1186/1471-2121-14-23 Bergsmedh, 2001, Horizontal transfer of oncogenes by uptake of apoptotic bodies, Proc. Natl. Acad. Sci. U.S.A., 98, 6407, 10.1073/pnas.101129998 Jia, 2014, Emerging technologies in extracellular vesicle-based molecular diagnostics, Expert Rev. Mol. Diagn., 14, 307, 10.1586/14737159.2014.893828 Melo, 2015, Glypican-1 identifies cancer exosomes and detects early pancreatic cancer, Nature, 523, 177, 10.1038/nature14581 Esselman, 1977, Modulation of B cell responses by glycolipid released from antigen-stimulated T cells, J. Immunol., 119, 1994, 10.4049/jimmunol.119.6.1994 Freimuth, 1979, Soluble factors containing Thy-1 antigen shed from lymphoblastoid cells modulate in vitro plaque-forming cell response, J. Immunol., 123, 201, 10.4049/jimmunol.123.1.201 Harding, 1983, Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes, J. Cell Biol., 97, 329, 10.1083/jcb.97.2.329 Pan, 1983, Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor, Cell, 33, 967, 10.1016/0092-8674(83)90040-5 Colombo, 2014, Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles, Annu. Rev. Cell Dev. Biol., 30, 10.1146/annurev-cellbio-101512-122326 Johnstone, 1987, Vesicle formation during reticulocyte maturation Association of plasma membrane activities with released vesicles (exosomes), J. Biol. Chem., 262, 9412, 10.1016/S0021-9258(18)48095-7 Lo Cicero, 2015, Extracellular vesicles shuffling intercellular messages: for good or for bad, Curr. Opin. Cell Biol., 35, 69, 10.1016/j.ceb.2015.04.013 Boulanger, 2006, Circulating microparticles: a potential prognostic marker for atherosclerotic vascular disease, Hypertension, 48, 180, 10.1161/01.HYP.0000231507.00962.b5 Morello, 2013, Large oncosomes mediate intercellular transfer of functional microRNA, Cell Cycle, 12, 3526, 10.4161/cc.26539 Minciacchi, 2015, Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes, Semin. Cell Dev. Biol., 40, 41, 10.1016/j.semcdb.2015.02.010 Gupta, 2006, Cancer metastasis: building a framework, Cell, 127, 679, 10.1016/j.cell.2006.11.001 Hanahan, 2011, Hallmarks of cancer: the next generation, Cell, 144, 646, 10.1016/j.cell.2011.02.013 Hanahan, 2000, The hallmarks of cancer, Cell, 100, 57, 10.1016/S0092-8674(00)81683-9 Al-Nedawi, 2008, Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells, Nat. Cell Biol., 10, 619, 10.1038/ncb1725 Lee, 2014, Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells, Biochem. Biophys. Res. Commun., 451, 295, 10.1016/j.bbrc.2014.07.109 Al-Nedawi, 2009, Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR, Proc. Natl. Acad. Sci. U.S.A., 106, 3794, 10.1073/pnas.0804543106 Yu, 2005, Oncogenic events regulate tissue factor expression in colorectal cancer cells: Implications for tumor progression and angiogenesis, Blood, 105, 1734, 10.1182/blood-2004-05-2042 Johnston, 2009, Competitive interactions between cells: death, growth, and geography, Science, 324, 1679, 10.1126/science.1163862 Dejosez, 2013, Safeguards for cell cooperation in mouse embryogenesis shown by genome-wide cheater screen, Science, 341, 1511, 10.1126/science.1241628 Vincent, 2013, Mechanisms and mechanics of cell competition in epithelia, Nat. Rev. Mol. Cell Biol., 14, 581, 10.1038/nrm3639 Kosaka, 2012, Competitive interactions of cancer cells and normal cells via secretory microRNAs, J. Biol. Chem., 287, 1397, 10.1074/jbc.M111.288662 Ono, 2014, Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells, Sci. Signal., 7, ra63, 10.1126/scisignal.2005231 Aguirre-Ghiso, 2007, Models, mechanisms and clinical evidence for cancer dormancy, Nat. Rev. Cancer, 7, 834, 10.1038/nrc2256 Lowe, 2004, Intrinsic tumour suppression, Nature, 432, 307, 10.1038/nature03098 Antonyak, 2011, Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells, Proc. Natl. Acad. Sci. U.S.A., 108, 17569, 10.1073/pnas.1017667108 Cardone, 2005, The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis, Nat. Rev. Cancer, 5, 786, 10.1038/nrc1713 Parks, 2011, pH control mechanisms of tumor survival and growth, J. Cell. Physiol., 226, 299, 10.1002/jcp.22400 Parolini, 2009, Microenvironmental pH is a key factor for exosome traffic in tumor cells, J. Biol. Chem., 284, 34211, 10.1074/jbc.M109.041152 Wang, 2014, Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis, Proc. Natl. Acad. Sci. U.S.A., 111, E3234, 10.1073/pnas.1410041111 Balaj, 2011, Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences, Nat. Commun., 2, 180, 10.1038/ncomms1180 Vogt, 2004, Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas, Proc. Natl. Acad. Sci. U.S.A., 101, 11368, 10.1073/pnas.0402979101 Shimizu, 2009, Extrachromosomal double minutes and chromosomal homogeneously staining regions as probes for chromosome research, Cytogenet. Genome Res., 124, 312, 10.1159/000218135 Kahlert, 2014, Identification of double-stranded genomic dna spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer, J. Biol. Chem., 289, 3869, 10.1074/jbc.C113.532267 García-Olmo, 2010, Cell-free nucleic acids circulating in the plasma of colorectal cancer patients induce the oncogenic transformation of susceptible cultured cells, Cancer Res., 70, 560, 10.1158/0008-5472.CAN-09-3513 Kanada, 2015, Differential fates of biomolecules delivered to target cells via extracellular vesicles, Proc. Natl. Acad. Sci. U.S.A., 112, E1433, 10.1073/pnas.1418401112 Orimo, 2005, Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion, Cell, 121, 335, 10.1016/j.cell.2005.02.034 Liang, 2005, Myofibroblasts correlate with lymphatic microvessel density and lymph node metastasis in early-stage invasive colorectal carcinoma, Anticancer Res., 25, 2705 Webber, 2010, Cancer exosomes trigger fibroblast to myofibroblast differentiation, Cancer Res., 70, 9621, 10.1158/0008-5472.CAN-10-1722 Webber, 2015, Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes, Oncogene, 34, 319, 10.1038/onc.2013.560 Bhowmick, 2004, TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia, Science, 303, 848, 10.1126/science.1090922 Luga, 2012, Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration, Cell, 151, 1542, 10.1016/j.cell.2012.11.024 Gray, 2011, Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity, Dev. Cell, 21, 120, 10.1016/j.devcel.2011.06.011 Boelens, 2014, Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways, Cell, 159, 499, 10.1016/j.cell.2014.09.051 Sung, 2015, Directional cell movement through tissues is controlled by exosome secretion, Nat. Commun., 6, 7164, 10.1038/ncomms8164 Hoshino, 2015, Tumour exosome integrins determine organotropic metastasis, Nature, 527, 329, 10.1038/nature15756 Peinado, 2011, The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts, Semin. Cancer Biol., 21, 139, 10.1016/j.semcancer.2011.01.002 Kaplan, 2005, VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche, Nature, 438, 820, 10.1038/nature04186 Peinado, 2012, Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET, Nat. Med., 18, 883, 10.1038/nm.2753 Costa-Silva, 2015, Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver, Nat. Cell Biol., 17, 816, 10.1038/ncb3169 Zhou, 2014, Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis, Cancer Cell, 25, 501, 10.1016/j.ccr.2014.03.007 Zhang, 2015, Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth, Nature, 527, 100, 10.1038/nature15376 Valadi, 2007, Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells, Nat. Cell Biol., 9, 654, 10.1038/ncb1596 Redzic, 2014, Extracellular RNA mediates and marks cancer progression, Semin. Cancer Biol., 28, 14, 10.1016/j.semcancer.2014.04.010 Squadrito, 2014, Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells, Cell Rep., 8, 1432, 10.1016/j.celrep.2014.07.035 Chevillet, 2014, Quantitative and stoichiometric analysis of the microRNA content of exosomes, Proc. Natl. Acad. Sci. U.S.A., 111, 14888, 10.1073/pnas.1408301111 Maas, 2015, Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics, J. Control. Release, 200, 87, 10.1016/j.jconrel.2014.12.041 Vaupel, 2004, Tumor microenvironmental physiology and its implications for radiation oncology, Semin. Radiat. Oncol., 14, 198, 10.1016/j.semradonc.2004.04.008 Kucharzewska, 2013, Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development, Proc. Natl. Acad. Sci. U.S.A., 110, 7312, 10.1073/pnas.1220998110 Skog, 2008, Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers, Nat. Cell Biol., 10, 1470, 10.1038/ncb1800 Semenza, 2012, Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy, Trends Pharmacol. Sci., 33, 207, 10.1016/j.tips.2012.01.005 Verweij, 2011, LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation, EMBO J., 30, 2115, 10.1038/emboj.2011.123 Meckes, 2010, Human tumor virus utilizes exosomes for intercellular communication, Proc. Natl. Acad. Sci. U.S.A., 107, 20370, 10.1073/pnas.1014194107 Aga, 2014, Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes, Oncogene, 33, 4613, 10.1038/onc.2014.66 Schäfer, 2008, Cancer as an overhealing wound: an old hypothesis revisited, Nat. Rev. Mol. Cell Biol., 9, 628, 10.1038/nrm2455 Chen, 2013, Oncology meets immunology: the cancer-immunity cycle, Immunity, 39, 1, 10.1016/j.immuni.2013.07.012 Noy, 2014, Tumor-associated macrophages: from mechanisms to therapy, Immunity, 41, 49, 10.1016/j.immuni.2014.06.010 Fabbri, 2012, MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response, Proc. Natl. Acad. Sci. U.S.A., 109, E2110, 10.1073/pnas.1209414109 Matzinger, 1994, Tolerance, danger, and the extended family, Annu. Rev. Immunol., 12, 991, 10.1146/annurev.iy.12.040194.005015 Buzas, 2014, Emerging role of extracellular vesicles in inflammatory diseases, Nat. Rev. Rheumatol., 10, 356, 10.1038/nrrheum.2014.19 Lehmann, 2012, An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration, Nat. Neurosci., 15, 827, 10.1038/nn.3113 Chow, 2014, Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB, Sci. Rep., 4, 5750, 10.1038/srep05750 Pardoll, 2012, The blockade of immune checkpoints in cancer immunotherapy, Nat. Rev. Cancer, 12, 252, 10.1038/nrc3239 Wieckowski, 2009, Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes, J. Immunol., 183, 3720, 10.4049/jimmunol.0900970 Zhang, 2011, Exosomes and cancer: a newly described pathway of immune suppression, Clin. Cancer Res., 17, 959, 10.1158/1078-0432.CCR-10-1489 Valenti, 2006, Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-β-mediated suppressive activity on T lymphocytes, Cancer Res., 66, 9290, 10.1158/0008-5472.CAN-06-1819 Antonyak, 2015, Emerging picture of the distinct traits and functions of microvesicles and exosomes, Proc. Natl. Acad. Sci. U.S.A., 112, 3589, 10.1073/pnas.1502590112 Sadovska, 2015, Biodistribution, uptake and effects caused by cancer-derived extracellular vesicles, J. Circ. Biomarkers, 10.5772/60522 Lai, 2015, Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters, Nat. Commun., 6, 7029, 10.1038/ncomms8029 Lai, 2014, Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter, ACS Nano., 8, 483, 10.1021/nn404945r Takahashi, 2013, Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection, J. Biotechnol., 165, 77, 10.1016/j.jbiotec.2013.03.013 Shen, 2011, Protein targeting to exosomes/microvesicles by plasma membrane anchors, J. Biol. Chem., 286, 14383, 10.1074/jbc.M110.208660 Ridder, 2014, Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation, PLoS Biol., 12, e1001874, 10.1371/journal.pbio.1001874 Zomer, 2015, In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior, Cell, 161, 1046, 10.1016/j.cell.2015.04.042