Anaesthesia for liver transplantation in two infants with an organic acidaemia

Pediatric Transplantation - Tập 10 Số 5 - Trang 623-628 - 2006
Diego Manzoni1, Angelica Spotti1, Bruno Carrara1, Paolo Gritti1, Valter Sonzogni1
1Department of Anaesthesia and Intensive Care 1, Ospedali Riuniti di Bergamo, Bergamo, Italy

Tóm tắt

Abstract:  Liver transplantation is an accepted option of treatment in patients with inborn errors of metabolism limited to or mainly located into hepatocytes who have not responded well to medical treatment. Recurrent metabolic failure and neurological impairment might be an indication for early transplantation in patients with organic acidaemias. We discuss the anaesthetic management and metabolic implications of acidaemia in the first two cases of successfully treated propionic and methylmalonic acidaemia in Italy. A nine and 12 month follow up did not show any further metabolic failure after the procedure, indicating that early liver transplantation improves the quality of life of these patients.

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Thông tin xuất bản

Pediatric Transplantation

Tập 10 Số 5

623-628

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