Positive feedback interactions between microtubule and actin dynamics during cell motility

Current Opinion in Cell Biology - Tập 11 - Trang 61-67 - 1999
Clare M Waterman-Storer1, ED Salmon1
1Department of Biology, 607 Fordham Hall, University of North Carolina, Chapel Hill, NC 27599-3280, USA

Tài liệu tham khảo

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Cell Motil Cytoskeleton 1999, in press. This paper examines microtubule dynamics in living migrating epithelial cells and documents differences in microtubule behavior that depend on subcellular location, such that microtubules at the leading edge exhibit net growth and microtubules at the inactive sides of cells are quiescent and shorten more. 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Cell Motil Cytoskeleton 1999, in press. Statistical correlations are drawn between parameters of dynamic instability, cell movement rates, and lamellipodial area in both control and taxol or nocodazole treated migrating cells. 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