PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells

Toxicology in Vitro - Tập 27 Số 6 - Trang 1762-1770 - 2013
Xiaobei Deng1, Fang Zhang1, Rui Wei1, Fang Long1, Lijuan Wang2, Zhaohan Feng3, Deliang Chen1, Wenjun Ding1
1Laboratory of Environment and Health, College of Life Sciences, University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, 100049, China
2Institute of Zoology, Chinese Academy of Sciences, Beichen Xi Road 1-5, Beijing 100101, China
3Department of Urology, China-Japan Friendship Hospital, Beijing 100029, China

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Abounit, 2012, Autophagy in mammalian cells, World Journal of Biological Chemistry, 3, 1, 10.4331/wjbc.v3.i1.1

Anderson, 2012, Clearing the air: a review of the effects of particulate matter air pollution on human health, Journal of Medical Toxicology, 8, 166, 10.1007/s13181-011-0203-1

Azad, 2009, Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment, Antioxidants & Redox Signaling, 11, 777, 10.1089/ars.2008.2270

Billet, 2007, Ambient particulate matter (PM2.5): physicochemical characterization and metabolic activation of the organic fraction in human lung epithelial cells (A549), Environmental Research, 105, 212, 10.1016/j.envres.2007.03.001

Brigelius-Flohé, 2009, Commentary: oxidative stress reconsidered, Genes & Nutrition, 4, 161, 10.1007/s12263-009-0131-8

Brunekreef, 2002, Air pollution and health, Lancet, 360, 1233, 10.1016/S0140-6736(02)11274-8

Cao, 2005, Characterization and source apportionment of atmospheric organic and elemental carbon during fall and winter of 2003 in Xi’an, China, Atmospheric Chemistry and Physics Discussions, 5, 3561, 10.5194/acpd-5-3561-2005

Chen, 2007, Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells, Cell Death & Differentiation, 15, 171, 10.1038/sj.cdd.4402233

Chen, 2012, Targeting protective autophagy exacerbates UV-triggered apoptotic cell death, International Journal of Molecular Sciences, 13, 1209, 10.3390/ijms13011209

Chirino, 2010, PM10 impairs the antioxidant defense system and exacerbates oxidative stress driven cell death, Toxicology Letters, 193, 209, 10.1016/j.toxlet.2010.01.009

Chow, 1996, Descriptive analysis of PM2.5 and PM10 at regionally representative locations during SJVAQS/AUSPEX, Atmospheric Environment, 30, 2079, 10.1016/1352-2310(95)00402-5

Fridovich, 1986, Biological effects of the superoxide radical, Archives of Biochemistry and Biophysics, 247, 1, 10.1016/0003-9861(86)90526-6

Geng, 2006, In vitro responses of rat alveolar macrophages to particle suspensions and water-soluble components of dust storm PM2.5, Toxicology in Vitro, 20, 575, 10.1016/j.tiv.2005.09.015

Ghio, 2012, Composition of air pollution particles and oxidative stress in cells, tissues, and living systems, Journal of Toxicology and Environmental Health, Part B, 15, 1, 10.1080/10937404.2012.632359

Gualtieri, 2009, Winter fine particulate matter from Milan induces morphological and functional alterations in human pulmonary epithelial cells (A549), Toxicology Letters, 188, 52, 10.1016/j.toxlet.2009.03.003

Gualtieri, 2010, Differences in cytotoxicity versus pro-inflammatory potency of different PM fractions in human epithelial lung cells, Toxicology in Vitro, 24, 29, 10.1016/j.tiv.2009.09.013

Gualtieri, 2012, Gene expression profiling of A549 cells exposed to Milan PM2.5, Toxicology Letters, 209, 136, 10.1016/j.toxlet.2011.11.015

Harrison, 2000, Particulate matter in the atmosphere: which particle properties are important for its effects on health?, Science of the Total Environment, 249, 85, 10.1016/S0048-9697(99)00513-6

Imrich, 2000, Insoluble components of concentrated air particles mediate alveolar macrophage responses in vitro, Toxicology and Applied Pharmacology, 167, 140, 10.1006/taap.2000.9002

Kiffin, 2006, Oxidative stress and autophagy, Antioxidants & Redox Signaling, 8, 152, 10.1089/ars.2006.8.152

Kiyono, 2009, Autophagy is activated by TGF-β and potentiates TGF-β-mediated growth inhibition in human hepatocellular carcinoma cells, Cancer Research, 69, 8844, 10.1158/0008-5472.CAN-08-4401

Knaapen, 2004, Inhaled particles and lung cancer. Part A: Mechanisms, International Journal of Cancer, 109, 799, 10.1002/ijc.11708

Koh, 2001, The effects of metallothionein on the activity of enzymes involved in removal of reactive oxygen species, Bulletin-Korean Chemical Society, 22, 362

Kondo, 2006, Autophagy and cancer therapy, Autophagy, 2, 85, 10.4161/auto.2.2.2463

Kouassi, 2010, Oxidative damage induced in A549 cells by physically and chemically characterized air particulate matter (PM2.5) collected in Abidjan, Côte d’Ivoire, Journal of Applied Toxicology, 30, 310, 10.1002/jat.1496

Lee, 2011, Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells, Archives of Toxicology, 85, 1529, 10.1007/s00204-011-0714-1

Leeuwenburgh, 2001, Oxidative stress and antioxidants in exercise, Current Medicinal Chemistry, 8, 829, 10.2174/0929867013372896

Levy, 2000, Estimating the mortality impacts of particulate matter: what can be learned from between-study variability?, Environmental Health Perspectives, 108, 109, 10.1289/ehp.00108109

Mosmann, 1983, Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays, Journal of Immunological Methods, 65, 55, 10.1016/0022-1759(83)90303-4

Pamplona, 2011, Molecular and structural antioxidant defenses against oxidative stress in animals, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 301, R843, 10.1152/ajpregu.00034.2011

Pope, 2002, Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution, JAMA: the Journal of the American Medical Association, 287, 1132, 10.1001/jama.287.9.1132

Riva, 2011, Low dose of fine particulate matter (PM2.5) can induce acute oxidative stress, inflammation and pulmonary impairment in healthy mice, Inhalation Toxicology, 23, 257, 10.3109/08958378.2011.566290

Van Limbergen, 2009, Autophagy: from basic science to clinical application, Mucosal Immunology, 2, 315, 10.1038/mi.2009.20

Viola, 2011, MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells, Biochemical Pharmacology, 83, 16, 10.1016/j.bcp.2011.09.017

Wei, 2011, Oxidative stress induced by urban fine particles in cultured EA. hy926 cells, Human & Experimental Toxicology, 30, 579, 10.1177/0960327110374207

White, 2009, The double-edged sword of autophagy modulation in cancer, Clinical Cancer Research, 15, 5308, 10.1158/1078-0432.CCR-07-5023

Wu, 2006, The signaling mechanism of ROS in tumor progression, Cancer and Metastasis Reviews, 25, 695, 10.1007/s10555-006-9037-8

Yi, 2012, Water-insoluble fraction of airborne particulate matter (PM10) induces oxidative stress in human lung epithelial A549 cells, Environmental Toxicology

Zhang, 2007, Comparison of cytotoxicity and genotoxicity induced by the extracts of methanol and gasoline engine exhausts, Toxicology in Vitro, 21, 1058, 10.1016/j.tiv.2007.04.001

Zhang, 2008, Characteristics of particulate carbon emissions from real-world Chinese coal combustion, Environmental Science & Technology, 42, 5068, 10.1021/es7022576

Zhang, 2009, Harmonizing molecular marker analyses of organic aerosols, Aerosol Science and Technology, 43, 275, 10.1080/02786820802609740