Framing expectations in early HIV cure research

Trends in Microbiology - Tập 22 - Trang 547-549 - 2014
Karine Dubé1, Gail E. Henderson2, David M. Margolis1
1Collaboratory of AIDS Researchers for Eradication (CARE), Institute for Global Health and Infectious Diseases (IGHID), The University of North Carolina at Chapel Hill, 120 Mason Farm Road, 2060 Genetic Medicine Building CB 7042, Chapel Hill, NC 27599-7042, USA
2Department of Social Medicine, School of Medicine, The University of North Carolina at Chapel Hill, 347A MacNider, Campus Box 7240, Chapel Hill, NC 27599-7240, USA

Tài liệu tham khảo

Horwitz, 1964, Nucleosides. V. The monomesylates of 1-(2′-deoxy-beta-Dlyxofuranosyl)thymidine, J. Org. Chem., 29, 2076, 10.1021/jo01030a546 Advisory Committee on Human Radiation Experiments, 1995 Prins, 1999, Immuno-activation with anti-CD3 and recombinant human IL-2 in HIV-1 infected patients on potent antiretroviral therapy, AIDS, 13, 2405, 10.1097/00002030-199912030-00012 Gordin, 2006, CD4+ count-guided interruption of antiretroviral treatment, N. Engl. J. Med., 355, 2283, 10.1056/NEJMoa062360 Allers, 2011, Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation, Blood, 117, 2791, 10.1182/blood-2010-09-309591 Persaud, 2013, Absence of detectable HIV-1 viremia after treatment cessation in an infant, N. Engl. J. Med., 369, 1828, 10.1056/NEJMoa1302976 Lehrman, 2005, Depletion of latent HIV-1 infection in vivo: a proof-of-concept study, Lancet, 366, 549, 10.1016/S0140-6736(05)67098-5 Archin, 2009, Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid, AIDS Res. Hum. Retroviruses, 25, 207, 10.1089/aid.2008.0191 Archin, 2014, HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat, J. Infect. Dis., 10.1093/infdis/jiu155 Saglio, 2014, The time is now: moving toward virus-specific T cells after allogeneic hematopoietic stem cell transplantation as the standard of care, Cytotherapy, 16, 149, 10.1016/j.jcyt.2013.11.010 Appelbaum, 1982, The therapeutic misconception: informed consent in psychiatric research, Int. J. Law Psychiatry, 5, 319, 10.1016/0160-2527(82)90026-7 Henderson, 2007, Clinical trials and medical care: defining the therapeutic misconception, PLoS Med., 4, 1735, 10.1371/journal.pmed.0040324