A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis
Tài liệu tham khảo
Davis, 2016, Glioblastoma: overview of disease and treatment, Clin J Oncol Nurs, 20, S2, 10.1188/16.CJON.S1.2-8
Ou, 2020, Molecular mechanisms of treatment resistance in glioblastoma, Int J Mol Sci, 22, 351, 10.3390/ijms22010351
Juratli, 2018, Molecular pathogenesis and therapeutic implications in pediatric high-grade gliomas, Pharmacol Ther, 182, 70, 10.1016/j.pharmthera.2017.08.006
Aldape, 2015, Glioblastoma: pathology, molecular mechanisms and markers, Acta Neuropathol, 129, 829, 10.1007/s00401-015-1432-1
Festuccia, 2020, Targeted molecular therapy in glioblastoma, J Oncol, 2020, 10.1155/2020/5104876
Iser, 2017, The epithelial-to-mesenchymal transition-like process in glioblastoma: an updated systematic review and in silico investigation, Med Res Rev, 37, 271, 10.1002/med.21408
Mittal, 2018, Epithelial mesenchymal transition in tumor metastasis, Annu Rev Pathol, 13, 395, 10.1146/annurev-pathol-020117-043854
Li, 2020, A potent CBP/p300-Snail interaction inhibitor suppresses tumor growth and metastasis in wild-type p53-expressing cancer, Sci Adv, 6, 10.1126/sciadv.aaw8500
Tao, 2020, Genomics and prognosis analysis of epithelial-mesenchymal transition in glioma, Front Oncol, 10, 183, 10.3389/fonc.2020.00183
Iwadate, 2016, Epithelial-mesenchymal transition in glioblastoma progression, Oncol Lett, 11, 1615, 10.3892/ol.2016.4113
Zhang, 2020, TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox 2 expression, Neuro Oncol, 22, 1797, 10.1093/neuonc/noaa138
Jimenez-Pascual, 2019, ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells, Cancer Discov, 9, 1574, 10.1158/2159-8290.CD-18-1308
Marseglia, 2019, Fibroblast growth factor receptor inhibitors: patent review (2015-2019), Expert Opin Ther Pat, 29, 965, 10.1080/13543776.2019.1688300
Turner, 2010, Fibroblast growth factor signalling: from development to cancer, Nat Rev Cancer, 10, 116, 10.1038/nrc2780
Katoh, 2014, FGF receptors: cancer biology and therapeutics, Med Res Rev, 34, 280, 10.1002/med.21288
Dai, 2019, Fibroblast growth factor receptors (FGFRs): structures and small molecule inhibitors, Cells, 8, E614, 10.3390/cells8060614
Jimenez-Pascual, 2019, Fibroblast growth factor receptor functions in glioblastoma, Cells, 8, 715, 10.3390/cells8070715
Touat, 2015, Targeting FGFR signaling in cancer, Clin Cancer Res, 21, 2684, 10.1158/1078-0432.CCR-14-2329
Koole, 2016, FGFR1 is a potential prognostic biomarker and therapeutic target in head and neck squamous cell carcinoma, Clin Cancer Res, 22, 3884, 10.1158/1078-0432.CCR-15-1874
Gouazé-Andersson, 2018, FGFR1/FOXM1 pathway: a key regulator of glioblastoma stem cells radioresistance and a prognosis biomarker, Oncotarget, 9, 31637, 10.18632/oncotarget.25827
Pennisi, 2009, FGFR-1 is required by epicardium-derived cells for myocardial invasion and correct coronary vascular lineage differentiation, Dev Biol, 328, 148, 10.1016/j.ydbio.2009.01.023
Zakrzewska, 2013, ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling, Sci Signal, 6, ra11, 10.1126/scisignal.2003087
Obenauer, 2003, Scansite 2.0:Proteome-wide prediction of cell signaling interactions using short sequence motifs, Nucleic Acids Res, 31, 3635, 10.1093/nar/gkg584
Hallinan, 2016, Targeting the fibroblast growth factor receptor family in cancer, Cancer Treat Rev, 46, 51, 10.1016/j.ctrv.2016.03.015
Weaver, 2021, Fibroblast growth factor receptor (FGFR) inhibitors: a review of a novel therapeutic class, J Oncol Pharm Pract, 27, 702, 10.1177/1078155220983425
Goodfellow, 2013, Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3, J Med Chem, 56, 8032, 10.1021/jm401094t
Jafari, 2014, The cellular thermal shift assay for evaluating drug target interactions in cells, Nat Protoc, 9, 2100, 10.1038/nprot.2014.138
Di, 2019, Discovery of a natural small-molecule compound that suppresses tumor EMT, stemness and metastasis by inhibiting TGFβ/BMP signaling in triple-negative breast cancer, J Exp Clin Cancer Res, 38, 134, 10.1186/s13046-019-1130-2
Babina, 2017, Advances and challenges in targeting FGFR signalling in cancer, Nat Rev Cancer, 17, 318, 10.1038/nrc.2017.8
Akinleye, 2013, Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics, J Hematol Oncol, 6, 88, 10.1186/1756-8722-6-88
Meng, 2018, Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling, Oncogene, 37, 5843, 10.1038/s41388-018-0392-z
Zhou, 2004, Dual regulation of Snail by GSK-3 beta-mediated phosphorylation in control of epithelial-mesenchymal transition, Nat Cell Biol, 6, 931, 10.1038/ncb1173
Bao, 2006, Glioma stem cells promote radioresistance by preferential activation of the DNA damage response, Nature, 444, 756, 10.1038/nature05236
Wang, 2016, Tenuigenin prevents IL-1β-induced inflammation in human osteoarthritis chondrocytes by suppressing PI3K/AKT/NF-κB signaling pathway, Inflammation, 39, 807, 10.1007/s10753-016-0309-3
He, 2021, Curcumol alleviates the inflammation of nucleus pulposus cells via the PI3K/Akt/NF-κB signaling pathway and delays intervertebral disk degeneration, World Neurosurg, 155, e402, 10.1016/j.wneu.2021.08.079
Hoesel, 2013, The complexity of NF-κB signaling in inflammation and cancer, Mol Cancer, 12, 86, 10.1186/1476-4598-12-86
Presta, 2017, Fibroblast growth factors (FGFs) in cancer: FGF traps as a new therapeutic approach, Pharmacol Ther, 179, 171, 10.1016/j.pharmthera.2017.05.013
Grose, 2005, Fibroblast growth factor signaling in tumorigenesis, Cytokine Growth Factor Rev, 16, 179, 10.1016/j.cytogfr.2005.01.003
Giacomini, 2016, Blocking the FGF/FGFR system as a “two-compartment” antiangiogenic/antitumor approach in cancer therapy, Pharmacol Res, 107, 172, 10.1016/j.phrs.2016.03.024
Peng, 2020, Resistance to FGFR1-targeted therapy leads to autophagy via TAK1/AMPK activation in gastric cancer, Gastric Cancer, 23, 988, 10.1007/s10120-020-01088-y
Mohammadi, 1996, Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction, Mol Cell Biol, 16, 977, 10.1128/MCB.16.3.977
Sørensen, 2008, Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus, Mol Cell Biol, 28, 4129, 10.1128/MCB.02117-07