Non-adenomatous sellar lesions: experience of a single centre and review of the literature

Springer Science and Business Media LLC - Tập 33 - Trang 465-476 - 2010
Maria Koutourousiou1, George Kontogeorgos2, Andreas Seretis1
1Department of Neurosurgery, “G. Gennimatas” Athens General Hospital, Athens, Greece
2Department of Pathology, G. Gennimatas Athens General Hospital, Athens, Greece

Tóm tắt

Non-adenomatous sellar lesions represent a diagnostic and occasionally a therapeutic challenge. The purpose of the study was to provide an overview of the clinical and radiographic characteristics of non-adenomatous sellar lesions operated at our department, with emphasis on treatment options. In our transsphenoidal surgical series of 300 cases, 29 non-adenomatous sellar lesions (9.7%) were identified by histology. Medical files and imaging findings were retrospectively analysed. Clinical presentation was usually a result of local mass effect. Imaging features were not always diagnostic. Of 29 non-adenomatous sellar lesions, total tumour excision with transsphenoidal surgery was achieved in 17, and no supplemental treatment was needed. Lesions partially resected were further treated with reoperation, radiation therapy, or medical therapy, tailored to individuals. In our experience, non-adenomatous sellar lesions represent a more prevalent clinical entity than expected. Pituitary surgeons should be aware of their existence to reconstruct treatment strategy, proceeding to adjuvant therapy when necessary.

Tài liệu tham khảo

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