Retrovirus Restriction Factors

Molecular Cell - Tập 16 - Trang 849-859 - 2004
Stephen P. Goff1
1Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University, 701 West 168th Street, New York, NY 10032 USA

Tài liệu tham khảo

Alce, 2004, APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein, J. Biol. Chem, 279, 34083, 10.1074/jbc.C400235200 Bassin, 1980, Macromolecular requirements for abrogation of Fv-1 restriction by murine leukemia viruses, J. Virol, 35, 287, 10.1128/JVI.35.2.287-297.1980 Beale, 2004, Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes, J. Mol. Biol, 337, 585, 10.1016/j.jmb.2004.01.046 Benit, 1997, Cloning of a new murine endogenous retrovirus, MuERV-L, with strong similarity to the human HERV-L element and with a gag coding sequence closely related to the Fv1 restriction gene, J. Virol, 71, 5652, 10.1128/JVI.71.7.5652-5657.1997 Berkhout, 1994, The unusual nucleotide content of the HIV RNA genome results in a biased amino acid composition of HIV proteins, Nucleic Acids Res, 22, 1705, 10.1093/nar/22.9.1705 Besnier, 2002, Restriction of lentivirus in monkeys, Proc. Natl. Acad. Sci. USA, 99, 11920, 10.1073/pnas.172384599 Besnier, 2003, Characterization of murine leukemia virus restriction in mammals, J. Virol, 77, 13403, 10.1128/JVI.77.24.13403-13406.2003 Best, 1996, Positional cloning of the mouse retrovirus restriction gene Fv1, Nature, 382, 826, 10.1038/382826a0 Bick, 2003, Expression of the zinc-finger antiviral protein inhibits alphavirus replication, J. Virol, 77, 11555, 10.1128/JVI.77.21.11555-11562.2003 Bishop, 2004, Cytidine deamination of retroviral DNA by diverse APOBEC proteins, Curr. Biol, 14, 1392, 10.1016/j.cub.2004.06.057 Bishop, 2004, APOBEC-mediated editing of viral RNA, Science, 305, 645, 10.1126/science.1100658 Bogerd, 2004, A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor, Proc. Natl. Acad. Sci. USA, 101, 3770, 10.1073/pnas.0307713101 Borden, 2002, Pondering the promyelocytic leukemia protein (PML) puzzle, Mol. Cell. Biol, 22, 5259, 10.1128/MCB.22.15.5259-5269.2002 Braaten, 2001, Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells, EMBO J, 20, 1300, 10.1093/emboj/20.6.1300 Braaten, 1996, Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription, J. Virol, 70, 3551, 10.1128/JVI.70.6.3551-3560.1996 Cen, 2004, The interaction between HIV-1 Gag and APOBEC3G, J. Biol. Chem, 279, 33177, 10.1074/jbc.M402062200 Conticello, 2003, The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G, Curr. Biol, 13, 2009, 10.1016/j.cub.2003.10.034 Cowan, 2002, Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism, Proc. Natl. Acad. Sci. USA, 99, 11914, 10.1073/pnas.162299499 de The, 1991, The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR, Cell, 66, 675, 10.1016/0092-8674(91)90113-D Decker, 1998, The exosome, Curr. Biol, 8, R238, 10.1016/S0960-9822(98)70149-6 DesGroseillers, 1983, Physical mapping of the Fv-1 tropism host range determinant of BALB/c murine leukemia viruses, J. Virol, 48, 685, 10.1128/JVI.48.3.685-696.1983 Dorfman, 1996, The human immunodeficiency virus type 1 capsid p2 domain confers sensitivity to the cyclophilin-binding drug SDZ NIM 811, J. Virol, 70, 5751, 10.1128/JVI.70.9.5751-5757.1996 Duran-Troise, 1981, Balb/3T3 cells chronically infected with N-tropic murine leukemia virus continue to express Fv-1b restriction, Virology, 112, 795, 10.1016/0042-6822(81)90329-9 Franke, 1994, Specific incorporation of cyclophilin A into HIV-1 virions, Nature, 372, 359, 10.1038/372359a0 Gamble, 1996, Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid, Cell, 87, 1285, 10.1016/S0092-8674(00)81823-1 Gao, 2002, Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein, Science, 297, 1703, 10.1126/science.1074276 Goff, 1996, Operating under a Gag order, Cell, 86, 691, 10.1016/S0092-8674(00)80141-5 Guo, 2004, The zinc finger antiviral protein directly binds to specific viral mRNAs through the CCCH zinc finger motifs, J. Virol, 78, 12781, 10.1128/JVI.78.23.12781-12787.2004 Harris, 2003, DNA deamination mediates innate immunity to retroviral infection, Cell, 113, 803, 10.1016/S0092-8674(03)00423-9 Harris, 2003, DNA deamination, Nat. Immunol, 4, 641, 10.1038/ni0703-641 Hatziioannou, 2003, Restriction of multiple divergent retroviruses by Lv1 and Ref1, EMBO J, 22, 385, 10.1093/emboj/cdg042 Hatziioannou, 2004, Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid, J. Virol, 78, 6005, 10.1128/JVI.78.11.6005-6012.2004 Hatziioannou, 2004, Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha, Proc. Natl. Acad. Sci. USA, 101, 10774, 10.1073/pnas.0402361101 Henry, 1998, B30.2-like domain proteins, Mol. Biol. Evol, 15, 1696, 10.1093/oxfordjournals.molbev.a025896 Himathongkham, 1996, Restriction of HIV-1 (subtype B) replication at the entry step in rhesus macaque cells, Virology, 219, 485, 10.1006/viro.1996.0276 Hofmann, 1999, Species-specific, postentry barriers to primate immunodeficiency virus infection, J. Virol, 73, 10020, 10.1128/JVI.73.12.10020-10028.1999 Ikeda, 1985, Characterization of a molecularly cloned retroviral sequence associated with Fv-4 resistance, J. Virol, 55, 768, 10.1128/JVI.55.3.768-777.1985 Ikeda, 1989, Fv-4 resistance gene, J. Virol, 63, 5405, 10.1128/JVI.63.12.5405-5412.1989 Ikeda, 2004, Influence of gag on human immunodeficiency virus type 1 species-specific tropism, J. Virol, 78, 11816, 10.1128/JVI.78.21.11816-11822.2004 Kai, 1976, Mouse strain resistant to N-, B-, and NB-tropic murine leukemia viruses, J. Virol, 20, 436, 10.1128/JVI.20.2.436-440.1976 Kai, 1986, Relationship between the cellular resistance to Friend murine leukemia virus infection and the expression of murine leukemia virus-gp70-related glycoprotein on cell surface of BALB/c-Fv-4wr mice, Virology, 150, 509, 10.1016/0042-6822(86)90315-6 Kao, 2003, Human immunodeficiency virus type 1 Vif is efficiently packaged into virions during productive but not chronic infection, J. Virol, 77, 1131, 10.1128/JVI.77.2.1131-1140.2003 Kao, 2003, The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity, J. Virol, 77, 11398, 10.1128/JVI.77.21.11398-11407.2003 Kao, 2004, Production of infectious human immunodeficiency virus type 1 does not require depletion of APOBEC3G from virus-producing cells, Retrovirology, 1, 27, 10.1186/1742-4690-1-27 Keckesova, 2004, The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities, Proc. Natl. Acad. Sci. USA, 101, 10780, 10.1073/pnas.0402474101 Kobayashi, 2004, APOBEC3G targets specific virus species, J. Virol, 78, 8238, 10.1128/JVI.78.15.8238-8244.2004 Kootstra, 2003, Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells, Proc. Natl. Acad. Sci. USA, 100, 1298, 10.1073/pnas.0337541100 Kozak, 1996, Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance, Virology, 225, 300, 10.1006/viro.1996.0604 Lander, 2001, Initial sequencing and analysis of the human genome, Nature, 409, 860, 10.1038/35057062 Lecossier, 2003, Hypermutation of HIV-1 DNA in the absence of the Vif protein, Science, 300, 1112, 10.1126/science.1083338 Liddament, 2004, APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo, Curr. Biol, 14, 1385, 10.1016/j.cub.2004.06.050 Lilly, 1967, Susceptibility to two strains of Friend leukemia virus in mice, Science, 155, 461, 10.1126/science.155.3761.461 Lilly, 1973, Genetic control of murine viral leukemogenesis, Adv. Cancer Res, 17, 231, 10.1016/S0065-230X(08)60532-1 Limjoco, 1993, Transgenic Fv-4 mice resistant to Friend virus, J. Virol, 67, 4163, 10.1128/JVI.67.7.4163-4168.1993 Liu, 2004, Influence of primate lentiviral Vif and proteasome inhibitors on human immunodeficiency virus type 1 virion packaging of APOBEC3G, J. Virol, 78, 2072, 10.1128/JVI.78.4.2072-2081.2004 Luban, 1993, Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B, Cell, 73, 1067, 10.1016/0092-8674(93)90637-6 Luo, 2004, Amino-terminal region of the human immunodeficiency virus type 1 nucleocapsid is required for human APOBEC3G packaging, J. Virol, 78, 11841, 10.1128/JVI.78.21.11841-11852.2004 Madani, 1998, An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein, J. Virol, 72, 10251, 10.1128/JVI.72.12.10251-10255.1998 Mangeat, 2003, Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts, Nature, 424, 99, 10.1038/nature01709 Mangeat, 2004, A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action, J. Biol. Chem, 279, 14481, 10.1074/jbc.C400060200 Mariani, 2003, Species-specific exclusion of AOPBEC3G from HIV-1 virions by Vif, Cell, 114, 21, 10.1016/S0092-8674(03)00515-4 Marin, 2003, HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation, Nat. Med, 9, 1398, 10.1038/nm946 Mehle, 2004, Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway, J. Biol. Chem, 279, 7792, 10.1074/jbc.M313093200 Melchior, 2003, Sumo, Trends Biochem. Sci, 28, 612, 10.1016/j.tibs.2003.09.002 Meyer, 2003, Cluster of TRIM genes in the human MHC class I region sharing the B30.2 domain, Tissue Antigens, 61, 63, 10.1034/j.1399-0039.2003.610105.x Mitchell, 1997, The exosome, Cell, 91, 457, 10.1016/S0092-8674(00)80432-8 Munk, 2002, A dominant block to HIV-1 replication at reverse transcription in simian cells, Proc. Natl. Acad. Sci. USA, 99, 13843, 10.1073/pnas.212400099 Nisole, S., Lynch, C., Stoye, J.P., and Yap, M.W. (2004). A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1. Proc. Natl. Acad. Sci. USA. Odaka, 1981, Fv-4, J. Natl. Cancer Inst, 67, 1123 Owens, 2003, Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells, J. Virol, 77, 726, 10.1128/JVI.77.1.726-731.2003 Owens, 2004, Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsid, J. Virol, 78, 5423, 10.1128/JVI.78.10.5423-5437.2004 Perron, 2004, TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells, Proc. Natl. Acad. Sci. USA, 101, 11827, 10.1073/pnas.0403364101 Pincus, 1971, A major genetic locus affecting resistance to infection with murine leukemia viruses. I. Tissue culture studies of naturally occuring viruses, J. Exp. Med, 133, 1219, 10.1084/jem.133.6.1219 Pincus, 1975, A major genetic locus affecting resistance to infection with murine leukemia viruses. IV. Dose-response relationships in Fv-1 sensitive and resistant cell cultures, Virology, 65, 333, 10.1016/0042-6822(75)90039-2 Pryciak, 1992, Fv-1 restriction and its effects on murine leukemia virus integration in vivo and in vitro, J. Virol, 66, 5959, 10.1128/JVI.66.10.5959-5966.1992 Reymond, 2001, The tripartite motif family identifies cell compartments, EMBO J, 20, 2140, 10.1093/emboj/20.9.2140 Sayah, 2004, Selection for loss of Ref1 activity in human cells releases HIV-1 from cyclophilin A dependence during infection, J. Virol, 78, 12066, 10.1128/JVI.78.21.12066-12070.2004 Sayah, 2004, Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1, Nature, 430, 569, 10.1038/nature02777 Schafer, 2004, Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor, Virology, 328, 163, 10.1016/j.virol.2004.08.006 Schrofelbauer, 2004, A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif), Proc. Natl. Acad. Sci. USA, 101, 3927, 10.1073/pnas.0307132101 Schwartz, 1998, Antiviral activity of the proteasome on incoming human immunodeficiency virus type 1, J. Virol, 72, 3845, 10.1128/JVI.72.5.3845-3850.1998 Shaheen, 2004, Co-receptor antagonists as HIV-1 entry inhibitors, Curr. Opin. Infect. Dis, 17, 7, 10.1097/00001432-200402000-00003 Sheehy, 2002, Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein, Nature, 418, 646, 10.1038/nature00939 Sheehy, 2003, The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif, Nat. Med, 9, 1404, 10.1038/nm945 Shibata, 1995, Early replication block of human immunodeficiency virus type 1 in monkey cells, J. Gen. Virol, 76, 2723, 10.1099/0022-1317-76-11-2723 Shindo, 2003, The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity, J. Biol. Chem, 278, 44412, 10.1074/jbc.C300376200 Simon, 1998, Evidence for a newly discovered cellular anti-HIV-1 phenotype, Nat. Med, 4, 1397, 10.1038/3987 Simon, 1998, The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted, EMBO J, 17, 1259, 10.1093/emboj/17.5.1259 Smit, 1999, Interspersed repeats and other mementos of transposable elements in mammalian genomes, Curr. Opin. Genet. Dev, 9, 657, 10.1016/S0959-437X(99)00031-3 Song, 2005, The B30.2 (SPRY) domain of the retroviral restriction factor TRIM5a exhibits lineage-specific length and sequence variation in primates, J. Virol, in press Stopak, 2003, HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability, Mol. Cell, 12, 591, 10.1016/S1097-2765(03)00353-8 Stoye, 2002, An intracellular block to primate lentivirus replication, Proc. Natl. Acad. Sci. USA, 99, 11549, 10.1073/pnas.192449399 Stremlau, 2004, The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys, Nature, 427, 848, 10.1038/nature02343 Suzuki, 1975, FV-4, Jpn. J. Exp. Med, 45, 473 Svarovskaia, 2004, Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs, J. Biol. Chem, 279, 35822, 10.1074/jbc.M405761200 Thali, 1994, Functional association of cyclophilin A with HIV-1 virions, Nature, 372, 363, 10.1038/372363a0 Towers, 2000, A conserved mechanism of retrovirus restriction in mammals, Proc. Natl. Acad. Sci. USA, 97, 12295, 10.1073/pnas.200286297 Towers, 2002, Abrogation of Ref1 retrovirus restriction in human cells, J. Virol, 76, 2548, 10.1128/jvi.76.5.2548-2550.2002 Towers, 2003, Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors, Nat. Med, 9, 1138, 10.1038/nm910 Turelli, 2004, Inhibition of hepatitis B virus replication by APOBEC3G, Science, 303, 1829, 10.1126/science.1092066 Turelli, 2004, The innate antiretroviral factor APOBEC3G does not affect human LINE-1 retrotransposition in a cell culture assay, J. Biol. Chem, 279, 43371, 10.1074/jbc.C400334200 Vajdos, 1997, Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein, Protein Sci, 6, 2297, 10.1002/pro.5560061103 Wichroski, M.J., Ichiyama, K., and Rana, T.M. (2004). Analysis of HIV-1 Vif-mediated proteasome-dependent depletion of APOBEC3G: Correlating function and subcellular localization. J. Biol. Chem., in press. Published online November 10, 2004. Wiegand, 2004, A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins, EMBO J, 23, 2451, 10.1038/sj.emboj.7600246 Xu, 2004, A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion, Proc. Natl. Acad. Sci. USA, 101, 5652, 10.1073/pnas.0400830101 Xu, 2003, BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta, Exp. Cell Res, 288, 84, 10.1016/S0014-4827(03)00187-3 Yap, 2003, Intracellular localisation of Fv1, Virology, 307, 76, 10.1016/S0042-6822(02)00053-3 Yap, 2004, Trim5alpha protein restricts both HIV-1 and murine leukemia virus, Proc. Natl. Acad. Sci. USA, 101, 10786, 10.1073/pnas.0402876101 Yoo, 1997, Molecular recognition in the HIV-1 capsid/cyclophilin A complex, J. Mol. Biol, 269, 780, 10.1006/jmbi.1997.1051 Yu, 2004, Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome, Nat Struct Mol Biol, 11, 435, 10.1038/nsmb758 Yu, 2003, Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex, Science, 302, 1056, 10.1126/science.1089591 Zennou, 2004, APOBEC3G incorporation into human immunodeficiency virus type 1 particles, J. Virol, 78, 12058, 10.1128/JVI.78.21.12058-12061.2004 Zhang, 2003, The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA, Nature, 424, 94, 10.1038/nature01707 Zheng, 2004, Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication, J. Virol, 78, 6073, 10.1128/JVI.78.11.6073-6076.2004