Daucosterol promotes the proliferation of neural stem cells

Reynolds, 1992, Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system, Science, 255, 1707, 10.1126/science.1553558 Lee, 2007, Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease, Nat. Med., 13, 439, 10.1038/nm1548 Jensen, 2013, Survival and differentiation of transplanted neural stem cells derived from human induced pluripotent stem cells in a rat stroke model, J. Stroke Cerebrovasc Dis., 22, 304, 10.1016/j.jstrokecerebrovasdis.2011.09.008 Yu, 2013, Enhanced connexin 43 expression following neural stem cell transplantation in a rat model of traumatic brain injury, Arch. Med. Sci., 9, 132, 10.5114/aoms.2012.31438 Li, 2011, Soluble NgR fusion protein modulates the proliferation of neural progenitor cells via the Notch pathway, Neurochem. Res., 36, 2363, 10.1007/s11064-011-0562-7 Wong, 2004, The role of epidermal growth factor and its receptors in mammalian CNS, Cytokine Growth Factor Rev., 15, 147, 10.1016/j.cytogfr.2004.01.004 Mason, 2007, Initiation to end point: the multiple roles of fibroblast growth factors in neural development, Nat. Rev. Neurosci., 8, 583, 10.1038/nrn2189 Bouic, 1996, Jaarsveld, beta-sitosterol and beta-sitosterol glucoside stimulate human peripheral blood lymphocyte proliferation: implications for their use as an immunomodulatory vitamin combination, Int. J. Immunopharmacol., 18, 693, 10.1016/S0192-0561(97)85551-8 Choi, 2012, Anti-inflammatory effects of β-sitosterol-β-d-glucoside from Trachelospermum jasminoides (Apocynaceae) in lipopolysaccharide-stimulated RAW 264.7 murine macrophages, Nat. Prod. Res., 26, 2340, 10.1080/14786419.2012.654608 Patrick, 1999, Plant sterols and sterolin: A review of their immune-modulating properties, Altern. Med. Rev., 4, 170 Lee, 2007, Immunoregulatory activity by daucosterol, a beta-sitosterol glycoside, induces protective Th1 immune response against disseminated Candidiasis in mice, Vaccine, 25, 3834, 10.1016/j.vaccine.2007.01.108 Guo, 2007, Cyclosporine affects the proliferation and differentiation of neural stem cells in culture, Neuroreport, 18, 863, 10.1097/WNR.0b013e32811d6d36 Ubezio, 2007, Antiproliferative activity of cisplatin detected by CFSE in p53-proficient and p53-deficient cells, Immunol. Invest., 36, 847, 10.1080/08820130701674836 Munson, 2010, An improved technique for calculating relative response in cellular proliferation experiment, Cytometry A, 77, 909, 10.1002/cyto.a.20935 Wang, 2011, Calcium prevents tumorigenesis in a mouse model of colorectal cancer, PloS One, 6, e22566, 10.1371/journal.pone.0022566 Azuaje, 2010, Coordinated modular functionality and prognostic potential of a heart failure biomarker-driven interaction network, BMC Syst. Biol., 4, 60, 10.1186/1752-0509-4-60 Iwai, 2002, Three steps of neural stem cells development in gerbil dentate gyrus after transient ischemia, J. Cereb. Blood Flow Metab., 22, 4ll, 10.1097/00004647-200204000-00005 Iwai, 2003, Temporal profile of stem cell division, migration, and differentiation from subventricular zone to olfactory bulb after transient forebrain ischemia in gerbils, J. Cereb. Blood Flow Metab., 23, 33l, 10.1097/01.WCB.0000050060.57184.E7 Monograph, 2001, Plant sterols and sterolins, Altern. Med. Rev., 6, 203 Salway, 1913, The synthetical preparation of d-glucosides of sitosterol, cholesterol and some fatty alcohols, J. Chem. Soc., 103, 1022, 10.1039/CT9130301022 Davenport, 1999, The mouse mitotic checkpoint gene bub1b, a novel bub1 family member, is expressed in a cell cycle-dependent manner, Genomics, 55, 113, 10.1006/geno.1998.5629 Bohers, 2008, Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy, Hum. Genet., 124, 473, 10.1007/s00439-008-0572-y Abal, 2007, APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation, Gastroenterology, 132, 2448, 10.1053/j.gastro.2007.03.027 Burum-Auensen, 2007, Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis, J Clin. Pathol., 60, 1403, 10.1136/jcp.2006.044305 Sethi, 1991, The CDC20 gene product of Saccharomyces cerevisiae, a beta-transducin homolog, is required for a subset of microtubule-dependent cellular processes, Mol. Cell Biol., 11, 5592, 10.1128/MCB.11.11.5592 Palmer, 1989, The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae, J. Cell Biol., 109, 3355, 10.1083/jcb.109.6.3355 Lim, 1998, Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast, Curr. Biol., 8, 231, 10.1016/S0960-9822(98)70088-0 Kitagawa, 2002, The Cdc20 homolog, FZY-1, and its interacting protein, IFY-1, are required for proper chromosome segregation in Caenorhabditis elegans, Curr. Biol., 12, 2118, 10.1016/S0960-9822(02)01392-1 Santamaria, 2011, The Plk1-dependent phosphoproteome of the early mitotic spindle, Mol. Cell Proteomics., 10, 10.1074/mcp.M110.004457 De Luca, 2006, A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association, Cell Cycle, 5, 296, 10.4161/cc.5.3.2392 Sumara, 2004, Roles of polo-like kinase 1 in the assembly of functional mitotic spindles, Curr. Biol., 14, 1712, 10.1016/j.cub.2004.09.049 Zhang, 2011, Interaction of Sororin protein with polo-like kinase 1 mediates resolution of chromosomal arm cohesion, J. Biol. Chem., 286, 41826, 10.1074/jbc.M111.305888 Giménez-Abián, 2004, Regulation of sister chromatid cohesion between chromosome arms, Curr. Biol., 14, 1187, 10.1016/j.cub.2004.06.052 Hansen, 2006, CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit, Proc. Nat. Acad. Sci. U.S.A., 103, 608, 10.1073/pnas.0509549102 Schmidt, 2005, Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity, Genes. Dev., 19, 502, 10.1101/gad.320705 Zimmerman, 2007, Polo-like kinase 3 is required for entry into S phase, Proc. Nat. Acad. Sci. U.S.A., 104, 1847, 10.1073/pnas.0610856104 Zhang, 1990, Characterization of fetal porcine bone sialoproteins, secreted phosphoprotein I (SPPI, osteopontin), bone sialoprotein, and a 23-kDa glycoprotein. Demonstration that the 23-kDa glycoprotein is derived from the carboxyl terminus of SPPI, J. Biol. Chem., 265, 7583, 10.1016/S0021-9258(19)39154-9 Reinholt, 1990, Osteopontin—a possible anchor of osteoclasts to bone, Proc. Nat. Acad. Sci. U.S.A., 87, 4473, 10.1073/pnas.87.12.4473 Boskey, 1993, Osteopontin-hydroxyapatite interactions in vitro: inhibition of hydroxyapatite formation and growth in a gelatin-gel, Bone Miner., 22, 147, 10.1016/S0169-6009(08)80225-5 Kalluri, 2012, Osteopontin increases the proliferation of neural progenitor cells, Int. J. Dev. Neurosci., 30, 359, 10.1016/j.ijdevneu.2012.04.003 Eichenlaub-Ritter, 2010, Chromosomal and cytoplasmic context determines predisposition to maternal age-related aneuploidy: brief overview and update on MCAK in mammalian oocytes, Biochem. Soc. Trans., 38, 1681, 10.1042/BST0381681 Yang, 2007, Identification of a novel mitotic phosphorylation motif associated with protein localization to the mitotic apparatus, J. Cell Sci., 120, 4060, 10.1242/jcs.014795 Lan, 2004, Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity, Curr. Biol., 14, 273, 10.1016/j.cub.2004.01.055 Wheatley, 2004, Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo, J. Biol. Chem., 279, 5655, 10.1074/jbc.M311299200 Zeitlin, 2001, CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis, J. Cell Biol., 155, 1147, 10.1083/jcb.200108125 Crosio, 2002, Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases, Mol. Cell Biol., 22, 874, 10.1128/MCB.22.3.874-885.2002 Zhang, 2012, The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores, J. Cell Sci., 125, 3243, 10.1242/jcs.104208 Sundin, 2010, Kinetochores: NDC80 toes the line, Curr. Biol., 20, R1083, 10.1016/j.cub.2010.11.033 D’Ercole, 1996, The role of the insulin-like growth factors in the central nervous system, Mol. Neurobiol., 13, 227, 10.1007/BF02740625 Popken, 2004, In vivo effects of insulin-like growth factor-I (IGF-I) on prenatal and early postnatal development of the central nervous system, Eur. J. Neurosci., 19, 2056, 10.1111/j.0953-816X.2004.03320.x Cheng, 2001, Endogenous IGF1 enhances cell survival in the postnatal dentate gyrus, J. Neurosci. Res., 64, 341, 10.1002/jnr.1084 Yan, 2006, Insulin-like growth factor-1 is an endogenous mediator of focal ischemia-induced neural progenitor proliferation, Eur. J. Neurosci., 24, 45, 10.1111/j.1460-9568.2006.04872.x Sanchez-Calderon, 2007, A network of growth and transcription factors controls neuronal differentiation and survival in the developing ear, Int. J. Dev. Biol., 51, 557, 10.1387/ijdb.072373hs Russo, 2005, The insulin-like growth factor system and its pleiotropic functions in brain, Endocr. Rev., 26, 916, 10.1210/er.2004-0024 Magariños, 2010, RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development, PLoS One, 5, e14435, 10.1371/journal.pone.0014435 Vanhaesebroeck, 2000, The PI3K-PDK1 connection: more than just a road to PKB, Biochem. J., 346, 561, 10.1042/bj3460561 Mairet-Coello, 2009, IGF-1 promotes G1/S cell cycle progression through bidirectional regulation of cyclins and CDK inhibitors via the PI3K/Akt pathway in developing rat cerebral cortex, J. Neurosci., 29, 775, 10.1523/JNEUROSCI.1700-08.2009 Polyak, 1994, p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest, Genes. Dev., 8, 9, 10.1101/gad.8.1.9 Toyoshima, 1994, p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21, Cell, 78, 67, 10.1016/0092-8674(94)90573-8 Kato, 1994, Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation, Cell, 79, 487, 10.1016/0092-8674(94)90257-7 Gyuris, 1993, Cdi1 a human G1 and S phase protein phosphatase that associates with Cdk2, Cell, 75, 791, 10.1016/0092-8674(93)90498-F Donato, 2002, Human HTm4 is a hematopoietic cell cycle regulator, J. Clin. Invest., 109, 51, 10.1172/JCI0214025