Regulation of ADMP and BMP2/4/7 at Opposite Embryonic Poles Generates a Self-Regulating Morphogenetic Field

Bertocchini, 2004, Determination of embryonic polarity in a regulative system: evidence for endogenous inhibitors acting sequentially during primitive streak formation in the chick embryo, Development, 131, 3381, 10.1242/dev.01178 Brivanlou, 2003, Stem cells. Setting standards for human embryonic stem cells, Science, 300, 913, 10.1126/science.1082940 Collavin, 2003, The secreted Frizzled-related protein Sizzled functions as a negative feedback regulator of extreme ventral mesoderm, Development, 130, 805, 10.1242/dev.00306 Dale, 2002, Xolloid-related: a novel BMP1/Tolloid-related metalloprotease is expressed during early Xenopus development, Mech. Dev., 119, 177, 10.1016/S0925-4773(02)00359-3 De Robertis, 2004, Dorsal-ventral patterning and neural induction in Xenopus embryos, Annu. Rev. Cell Dev. Biol., 20, 285, 10.1146/annurev.cellbio.20.011403.154124 Dosch, 2000, Requirement for anti-dorsalizing morphogenetic protein in organizer patterning, Mech. Dev., 90, 195, 10.1016/S0925-4773(99)00245-2 Enders, 2002, Implantation in the nine-banded armadillo: how does a single blastocyst form four embryos?, Placenta, 23, 71, 10.1053/plac.2001.0753 Harland, 2000, Neural induction, Curr. Opin. Genet. Dev., 10, 357, 10.1016/S0959-437X(00)00096-4 Harrison, 1918, Experiments on the development of the fore-limb of Amblystoma, a self-differentiating equipotential system, J. Exp. Zool., 25, 413, 10.1002/jez.1400250204 Huxley, 1934 Joubin, 1999, Molecular interactions continuously define the organizer during the cell movements of gastrulation, Cell, 98, 559, 10.1016/S0092-8674(00)80044-6 Khokha, 2005, Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures, Dev. Cell, 8, 401, 10.1016/j.devcel.2005.01.013 Kirschner, 2005, The meaning of systems biology, Cell, 121, 503, 10.1016/j.cell.2005.05.005 Klein, 1987, The first cleavage furrow demarcates the dorsal-ventral axis in Xenopus embryos, Dev. Biol., 120, 299, 10.1016/0012-1606(87)90127-8 Kuroda, 2004, Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus, PLoS Biol., 2, e92, 10.1371/journal.pbio.0020092 Larrain, 2001, Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling, Development, 128, 4439, 10.1242/dev.128.22.4439 Lele, 2001, Zebrafish admp is required to restrict the size of the organizer and to promote posterior and ventral development, Dev. Dyn., 222, 681, 10.1002/dvdy.1222 Macias-Silva, 1998, Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2, J. Biol. Chem., 273, 25628, 10.1074/jbc.273.40.25628 Meinhardt, 1992, Pattern formation in biology: a comparison of models and experiments, Rep. Prog. Phys., 55, 797, 10.1088/0034-4885/55/6/003 Moos, 1995, Anti-dorsalizing morphogenetic protein is a novel TGF-beta homolog expressed in the Spemann organizer, Development, 121, 4293, 10.1242/dev.121.12.4293 Munoz-Sanjuan, 2002, Neural induction, the default model and embryonic stem cells, Nat. Rev. Neurosci., 3, 271, 10.1038/nrn786 Neul, 1998, Spatially restricted activation of the SAX receptor by SCW modulates DPP/TKV signaling in Drosophila dorsal-ventral patterning, Cell, 95, 483, 10.1016/S0092-8674(00)81616-5 Niehrs, 2002, Modular feedback, Nature, 417, 35, 10.1038/417035a Niehrs, 1999, Synexpression groups in eukaryotes, Nature, 402, 483, 10.1038/990025 Oelgeschläger, 2003, Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos, Dev. Cell, 4, 219, 10.1016/S1534-5807(02)00404-5 Oelgeschläger, 2003, The pro-BMP activity of Twisted gastrulation is independent of BMP binding, Development, 130, 4047, 10.1242/dev.00633 Onichtchouk, 1999, Silencing of TGF-beta signalling by the pseudoreceptor BAMBI, Nature, 401, 480, 10.1038/46794 Piccolo, 1997, Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity, Cell, 91, 407, 10.1016/S0092-8674(00)80424-9 Reversade, 2005, Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos, Development, 132, 3381, 10.1242/dev.01901 Sadler, 2004 Schier, 2005, Molecular Genetics of Axis Formation in Zebrafish, Annu. Rev. Genet., 39, 561, 10.1146/annurev.genet.37.110801.143752 Shimmi, 2005, Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo, Cell, 120, 873, 10.1016/j.cell.2005.02.009 Smith, 1983, Dorsalization and neural induction: properties of the organizer in Xenopus laevis, J. Embryol. Exp. Morphol., 78, 299 Spemann, 1903, Entwicklungsphysiologische Studien am Tritonei III, Arch. f. Entw. Mech., 16, 551 Spemann, 1938 Spratt, 1960, Integrative mechanism in development of the early chick blastoderm. I. Regulative potentiality of separate parts, J. Exp. Zool., 145, 97, 10.1002/jez.1401450202 Stern, 2005, Neural induction: old problem, new findings, yet more questions, Development, 132, 2007, 10.1242/dev.01794 Wang, 2005, Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning, Nature, 434, 229, 10.1038/nature03318 Willot, 2002, Cooperative action of ADMP- and BMP-mediated pathways in regulating cell fates in the zebrafish gastrula, Dev. Biol., 241, 59, 10.1006/dbio.2001.0494 Yabe, 2003, Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling, Development, 130, 2705, 10.1242/dev.00506