Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions

Cell Reports Medicine - Tập 4 - Trang 101003 - 2023
Tom G. Caniels1,2, Max Medina-Ramírez1,2, Jinsong Zhang3, Anita Sarkar4, Sonu Kumar4, Alex LaBranche3, Ronald Derking1,2, Joel D. Allen5, Jonne L. Snitselaar1,2, Joan Capella-Pujol1,2, Iván del Moral Sánchez1,2, Anila Yasmeen6, Marilyn Diaz3, Yoann Aldon1,2, Tom P.L. Bijl1,2, Sravani Venkatayogi7, Joshua S. Martin Beem7, Amanda Newman7, Chuancang Jiang6, Wen-Hsin Lee4
1Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
2Amsterdam Institute for Infection and Immunity, Infectious Diseases, Amsterdam, the Netherlands
3Applied Biomedical Science Institute, San Diego, CA, USA
4Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA
5School of Biological Sciences, University of Southampton, Southampton, UK
6Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY, USA
7Department of Surgery, Duke University School of Medicine, Durham, NC USA

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