The ERK1/2 Signaling Pathway Regulates 11beta-Hydroxysteroid Dehydrogenase Type 2 Expression in Human Trophoblast Cells Through a Transcriptional Mechanism1
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1995, Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation, Genes Dev, 9, 1608, 10.1101/gad.9.13.1608
1995, Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need, Nature, 373, 427, 10.1038/373427a0
1994, Glucocorticoids and small babies, Q J Med, 87, 259
1997, Placental 11 beta-hydroxysteroid dehydrogenase: barrier to maternal glucocorticoids, Rev Reprod, 2, 129, 10.1530/ror.0.0020129
1999, Dual function of 11beta-hydroxysteroid dehydrogenase in placenta: modulating placental glucocorticoid passage and local steroid action, Biol Reprod, 60, 234, 10.1095/biolreprod60.2.234
1996, Apparent mineralocorticoid excess due to 11 beta-hydroxysteroid dehydrogenase deficiency: a possible cause of intrauterine growth retardation, Clin Endocrinol (Oxf), 44, 353, 10.1046/j.1365-2265.1996.677500.x
2009, Altered placental function of 11beta-hydroxysteroid dehydrogenase 2 knockout mice, Endocrinology, 150, 1287, 10.1210/en.2008-1100
1998, 11Beta-hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction, Hum Reprod, 13, 799, 10.1093/humrep/13.4.799
2001, Reduced placental 11beta-hydroxysteroid dehydrogenase type 2 mRNA levels in human pregnancies complicated by intrauterine growth restriction: an analysis of possible mechanisms, J Clin Endocrinol Metab, 86, 4979
2001, Decreased gene expression of 11beta-hydroxysteroid dehydrogenase type 2 and 15-hydroxyprostaglandin dehydrogenase in human placenta of patients with preeclampsia, J Clin Endocrinol Metab, 86, 1313
2003, Placental 11 beta-hydroxysteroid dehydrogenase-2 and fetal cortisol/cortisone shuttle in small preterm infants, J Clin Endocrinol Metab, 88, 493, 10.1210/jc.2002-021378
2007, Simultaneously reduced gene expression of cortisol-activating and cortisol-inactivating enzymes in placentas of small-for-gestational-age neonates, Am J Obstet Gynecol, 197, e1
2008, Placental 11beta-hydroxysteroid dehydrogenase type 2 is reduced in pregnancies complicated with idiopathic intrauterine growth restriction: evidence that this is associated with an attenuated ratio of cortisone to cortisol in the umbilical artery, Placenta, 29, 193, 10.1016/j.placenta.2007.10.010
2009, The p38 mitogen-activated protein kinase regulates 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) expression in human trophoblast cells through modulation of 11beta-HSD2 messenger ribonucleic acid stability, Endocrinology, 150, 4278, 10.1210/en.2009-0479
2006, Cadmium reduces 11 beta-hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells, Am J Physiol Endocrinol Metab, 290, E135, 10.1152/ajpendo.00356.2005
2012, Caffeine reduces 11beta-hydroxysteroid dehydrogenase type 2 expression in human trophoblast cells through the adenosine A(2B) receptor, PLoS One, 7, e38082, 10.1371/journal.pone.0038082
1986, Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae, Endocrinology, 118, 1567, 10.1210/endo-118-4-1567
2002, The expression of 11 beta-hydroxysteroid dehydrogenase type 2 is induced during trophoblast differentiation: effects of hypoxia, J Clin Endocrinol Metab, 87, 3696
2010, BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway, J Cell Physiol, 223, 658, 10.1002/jcp.22064
1995, Immunohistochemical localization of the 11 beta-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta, J Clin Endocrinol Metab, 80, 2203
2004, Glucocorticoids stimulate the expression of 11beta-hydroxysteroid dehydrogenase type 2 in cultured human placental trophoblast cells, J Clin Endocrinol Metab, 89, 5614, 10.1210/jc.2004-0113
2010, Prostasin regulates human placental trophoblast cell proliferation via the epidermal growth factor receptor signaling pathway, Hum Reprod, 25, 623, 10.1093/humrep/dep457
2010, EGF stimulates proliferation in the bovine placental trophoblast cell line F3 via Ras and MAPK, Placenta, 31, 67, 10.1016/j.placenta.2009.10.011
2013, CCN3 regulates proliferation and migration properties in Jeg3 trophoblast cells via ERK1/2, Akt and Notch signalling, Mol Hum Reprod, 19, 237, 10.1093/molehr/gas061
2009, Involvement of MAPK signalling in human villous trophoblast differentiation, Mini Rev Med Chem, 9, 962, 10.2174/138955709788681663
2008, Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway, Arch Biochem Biophys, 477, 390, 10.1016/j.abb.2008.06.015
2011, Cross talk between cAMP and p38 MAPK pathways in the induction of leptin by hCG in human placental syncytiotrophoblasts, Reproduction, 142, 369, 10.1530/REP-11-0053
2008, Effects of cadmium on MAPK signalling pathways and HSP70 expression in a human trophoblast cell line, Placenta, 29, 725, 10.1016/j.placenta.2008.05.004
1990, Regulation of 11 beta-hydroxysteroid dehydrogenase activity in the baboon placenta by estrogen, Endocrinology, 126, 2742, 10.1210/endo-126-5-2742
1999, Cloning of the 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-2 gene in the baboon: effects of estradiol on promoter activity of 11beta-HSD-1 and −2 in placental JEG-3 cells, Biochim Biophys Acta, 1444, 101, 10.1016/S0167-4781(98)00248-6
2001, Estrogen regulates 11 beta-hydroxysteroid dehydrogenase-1 and −2 localization in placental syncytiotrophoblast in the second half of primate pregnancy, Endocrinology, 142, 4496, 10.1210/endo.142.10.8434
2009, Role of human chorionic gonadotropin in maintaining 11beta-hydroxysteroid dehydrogenase type 2 expression in human placental syncytiotrophoblasts, Placenta, 30, 1023, 10.1016/j.placenta.2009.10.005
1999, Retinoic acid stimulates the expression of 11beta-hydroxysteroid dehydrogenase type 2 in human choriocarcinoma JEG-3 cells, Biol Reprod, 60, 541, 10.1095/biolreprod60.3.541
2003, Gestation-related and betamethasone-induced changes in 11beta-hydroxysteroid dehydrogenase types 1 and 2 in the baboon placenta, Am J Obstet Gynecol, 188, 13, 10.1067/mob.2003.62
1996, Regulation of 11 beta-hydroxysteroid dehydrogenase type 2 activity and mRNA in human choriocarcinoma cells, J Mol Endocrinol, 16, 269, 10.1677/jme.0.0160269
2011, The Sp1 transcription factor is crucial for the expression of 11beta-hydroxysteroid dehydrogenase type 2 in human placental trophoblasts, J Clin Endocrinol Metab, 96, E899, 10.1210/jc.2010-2852
1999, and leukotriene B4 are potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 2 activity in human choriocarcinoma JEG-3 cells, Biol Reprod, 61, 40, 10.1095/biolreprod61.1.40
1998, Regulation of 11beta-hydroxysteroid dehydrogenase type 2 by progesterone, estrogen, and the cyclic adenosine 5′-monophosphate pathway in cultured human placental and chorionic trophoblasts, Biol Reprod, 58, 1379, 10.1095/biolreprod58.6.1379
2006, Hypoxia blocks 11beta-hydroxysteroid dehydrogenase type 2 induction in human trophoblast cells during differentiation by a time-dependent mechanism that involves both translation and transcription, Placenta, 27, 832, 10.1016/j.placenta.2005.09.006