The GABAA Receptor β Subunit Is Required for Inhibitory Transmission

Neuron - Tập 98 - Trang 718-725.e3 - 2018
Quynh-Anh Nguyen1, Roger A. Nicoll2,3
1Neuroscience Graduate Program, University of California San Francisco, San Francisco, CA 94158, USA
2Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158, USA
3Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA

Tài liệu tham khảo

Bezaire, 2013, Quantitative assessment of CA1 local circuits: knowledge base for interneuron-pyramidal cell connectivity, Hippocampus, 23, 751, 10.1002/hipo.22141 Cathala, 2000, Developmental profile of the changing properties of NMDA receptors at cerebellar mossy fiber-granule cell synapses, J. Neurosci., 20, 5899, 10.1523/JNEUROSCI.20-16-05899.2000 Chang, 1996, Stoichiometry of a recombinant GABAA receptor, J. Neurosci., 16, 5415, 10.1523/JNEUROSCI.16-17-05415.1996 Chen, 2016, Hunger neurons drive feeding through a sustained, positive reinforcement signal, eLife, 5, 5, 10.7554/eLife.18640 Chiu, 2018, Input-specific NMDAR-dependent potentiation of dendritic GABAergic inhibition, Neuron, 97, 368, 10.1016/j.neuron.2017.12.032 Di Cristo, 2004, Subcellular domain-restricted GABAergic innervation in primary visual cortex in the absence of sensory and thalamic inputs, Nat. Neurosci., 7, 1184, 10.1038/nn1334 Drexler, 2009, Distinct actions of etomidate and propofol at beta3-containing gamma-aminobutyric acid type A receptors, Neuropharmacology, 57, 446, 10.1016/j.neuropharm.2009.06.014 Fritschy, 2014, GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system, Eur. J. Neurosci., 39, 1845, 10.1111/ejn.12534 Gingrich, 1995, Dependence of the GABAA receptor gating kinetics on the alpha-subunit isoform: implications for structure-function relations and synaptic transmission, J. Physiol., 489, 529, 10.1113/jphysiol.1995.sp021070 Gray, 2011, Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo, Neuron, 71, 1085, 10.1016/j.neuron.2011.08.007 Herd, 2008, The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells, J. Physiol., 586, 989, 10.1113/jphysiol.2007.146746 Incontro, 2014, Efficient, complete deletion of synaptic proteins using CRISPR, Neuron, 83, 1051, 10.1016/j.neuron.2014.07.043 Jechlinger, 1998, Subunit composition and quantitative importance of hetero-oligomeric receptors: GABAA receptors containing alpha6 subunits, J. Neurosci., 18, 2449, 10.1523/JNEUROSCI.18-07-02449.1998 Kosaka, 1987, GABAergic neurons containing the Ca2+-binding protein parvalbumin in the rat hippocampus and dentate gyrus, Brain Res., 419, 119, 10.1016/0006-8993(87)90575-0 Laurie, 1992, The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development, J. Neurosci., 12, 4151, 10.1523/JNEUROSCI.12-11-04151.1992 Lee, 2014, Pyramidal neurons in prefrontal cortex receive subtype-specific forms of excitation and inhibition, Neuron, 81, 61, 10.1016/j.neuron.2013.10.031 Li, 1997, Coexistence of two beta subunit isoforms in the same gamma-aminobutyric acid type A receptor, J. Biol. Chem., 272, 16564, 10.1074/jbc.272.26.16564 Nusser, 2001, Disruption of GABA(A) receptors on GABAergic interneurons leads to increased oscillatory power in the olfactory bulb network, J. Neurophysiol., 86, 2823, 10.1152/jn.2001.86.6.2823 Oh, 2017, Using a novel PV-Cre rat model to characterize pallidonigral cells and their terminations, Brain Struct. Funct., 222, 2359, 10.1007/s00429-016-1346-2 Olsen, 2008, International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update, Pharmacol. Rev., 60, 243, 10.1124/pr.108.00505 Ramadan, 2003, GABA(A) receptor beta3 subunit deletion decreases alpha2/3 subunits and IPSC duration, J. Neurophysiol., 89, 128, 10.1152/jn.00700.2002 Ran, 2013, Genome engineering using the CRISPR-Cas9 system, Nat. Protoc., 8, 2281, 10.1038/nprot.2013.143 Rudolph, 2004, Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics, Annu. Rev. Pharmacol. Toxicol., 44, 475, 10.1146/annurev.pharmtox.44.101802.121429 Rudy, 2011, Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons, Dev. Neurobiol., 71, 45, 10.1002/dneu.20853 Sanjana, 2014, Improved vectors and genome-wide libraries for CRISPR screening, Nat. Methods, 11, 783, 10.1038/nmeth.3047 Schnell, 2002, Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number, Proc. Natl. Acad. Sci. USA, 99, 13902, 10.1073/pnas.172511199 Sieghart, 2006, Structure, pharmacology, and function of GABAA receptor subtypes, Adv. Pharmacol., 54, 231, 10.1016/S1054-3589(06)54010-4 Sieghart, 2002, Subunit composition, distribution and function of GABA(A) receptor subtypes, Curr. Top. Med. Chem., 2, 795, 10.2174/1568026023393507 Simon, 2004, Analysis of the set of GABA(A) receptor genes in the human genome, J. Biol. Chem., 279, 41422, 10.1074/jbc.M401354200 Somogyi, 2005, Defined types of cortical interneurone structure space and spike timing in the hippocampus, J. Physiol., 562, 9, 10.1113/jphysiol.2004.078915 Song, 2011, Tonic excitation or inhibition is set by GABA(A) conductance in hippocampal interneurons, Nat. Commun., 2, 376, 10.1038/ncomms1377 Sperk, 1997, GABA(A) receptor subunits in the rat hippocampus I: immunocytochemical distribution of 13 subunits, Neuroscience, 80, 987, 10.1016/S0306-4522(97)00146-2 Stoppini, 1991, A simple method for organotypic cultures of nervous tissue, J. Neurosci. Methods, 37, 173, 10.1016/0165-0270(91)90128-M Straub, 2014, CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons, PLoS ONE, 9, e105584, 10.1371/journal.pone.0105584 Sur, 2001, Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice, J. Neurosci., 21, 3409, 10.1523/JNEUROSCI.21-10-03409.2001 Xie, 2013, Target-specific IPSC kinetics promote temporal processing in auditory parallel pathways, J. Neurosci., 33, 1598, 10.1523/JNEUROSCI.2541-12.2013 Xu, 2010, Immunochemical characterization of inhibitory mouse cortical neurons: three chemically distinct classes of inhibitory cells, J. Comp. Neurol., 518, 389, 10.1002/cne.22229