Fructose: Metabolic, Hedonic, and Societal Parallels with Ethanol
Tài liệu tham khảo
2004, Trends in intake of energy and macronutrients—United States, 1971-2000, Morb Mortal Wkly Rep, 53, 80
Zivkovic, 2007, Comparative review of diets for the metabolic syndrome: Implications for nonalcoholic fatty liver disease, Am J Clin Nutr, 86, 285, 10.1093/ajcn/86.2.285
Cave, 2007, Nonalcoholic fatty liver disease: Predisposing factors and the role of nutrition, J Nutr Biochem, 18, 184, 10.1016/j.jnutbio.2006.12.006
Alkouri, 2009, Lipotoxicity in nonalcoholic fatty liver disease: Not all lipids are created equal, Expert Rev Gastroenterol Hepatol, 3, 445, 10.1586/egh.09.32
Verna, 2008, Role of fatty acids in the pathogenesis of obesity and fatty liver: Impact of bariatric surgery, Semin Liver Dis, 28, 407, 10.1055/s-0028-1091985
Tetri, 2008, Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent, Am J Physiol Gastrointest Liver Physiol, 295, G987, 10.1152/ajpgi.90272.2008
Nagao, 2005, Dietary conjugated linoleic acid alleviates nonalcoholic fatty liver disease in Zucker (fa/fa) rats, J Nutr, 135, 9, 10.1093/jn/135.1.9
Assy, 2009, Olive oil consumption and non-alcoholic fatty liver disease, World J Gastroenterol, 15, 1809, 10.3748/wjg.15.1809
Chanmugam, 2003, Did fat intake in the United States really decline between 1989-1991 and 1994-1996?, J Am Diet Assoc, 103, 867, 10.1016/S0002-8223(03)00381-X
York, 2009, Nonalcoholic fatty liver disease and low-carbohydrate diets, Ann Rev Nutr, 29, 365, 10.1146/annurev-nutr-070208-114232
Facchini, 1994, Light-to-moderate alcohol intake is associated with enhanced insulin sensitivity, Diabetes Care, 17, 115, 10.2337/diacare.17.2.115
Di Castelnuovo, 2009, Alcohol consumption and cardiovascular risk: Mechanisms of action and epidemiologic perspectives, Future Cardiol, 5, 467, 10.2217/fca.09.36
Athyros, 2007, Association of drinking pattern and alcohol beverage type with the prevalence of metabolic syndrome, diabetes, coronary heart disease, stroke, and peripheral arterial disease in a Mediterranean cohort, Angiology, 58, 689, 10.1177/0003319707306146
Sakurai, 1997, Relation of total and beverage-specific alcohol intake to body mass index and waist-to-hip ratio: A study of self-defense officials in Japan, Eur J Epidemiol, 13, 893, 10.1023/A:1007416322031
Baik, 2008, Prospective study of alcohol consumption and metabolic syndrome, Am J Clin Nutr, 87, 1455, 10.1093/ajcn/87.5.1455
Vos, 2008, Dietary fructose consumption among US children and adults: The Third National Health and Nutrition Examination Survey, Medscape J Med, 10, 160
Ludwig, 2001, Relation between consumption of sugar-sweetened drinks and childhood obesity: A prospective, observational analysis, Lancet, 357, 505, 10.1016/S0140-6736(00)04041-1
Warner, 2006, Soda consumption and overweight status of 2-year-old Mexican-American children in California, Obesity, 14, 1966, 10.1038/oby.2006.230
Faith, 2006, Fruit juice intake predicts increased adiposity gain in children from low-income families: Weight status-by-environment interaction, Pediatrics, 118, 2066, 10.1542/peds.2006-1117
Le, 2006, Metabolic effects of fructose, Curr Opin Nutr Metab Care, 9, 469, 10.1097/01.mco.0000232910.61612.4d
Rutledge, 2007, Fructose and the metabolic syndrome: Pathophysiology and molecular mechanisms, Nutr Rev, 65, S13, 10.1301/nr.2007.jun.S13-S23
Johnson, 2007, Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease, Am J Clin Nutr, 86, 899
Havel, 2005, Dietary fructose: Implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism, Nutr Rev, 63, 133, 10.1111/j.1753-4887.2005.tb00132.x
Gross, 2004, Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: An ecologic assessment, Am J Clin Nutr, 79, 774, 10.1093/ajcn/79.5.774
Elliott, 2002, Fructose, weight gain, and the insulin resistance syndrome, Am J Clin Nutr, 76, 911, 10.1093/ajcn/76.5.911
Dhingra, 2007, Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community, Circulation, 116, 480, 10.1161/CIRCULATIONAHA.107.689935
Brown, 2008, Sugary drinks in the pathogenesis of obesity and cardiovascular diseases, Int J Obes, 32, 528, 10.1038/ijo.2008.204
Bolton-Smith, 1990, Dietary composition and fat to sugar ratios in relation to obesity, Int J Obes, 18, 820
Johnson, 2009, Dietary sugars intake and cardiovascular health, Circulation, 120, 1011, 10.1161/CIRCULATIONAHA.109.192627
Reaven, 2006, The metabolic syndrome: Is this diagnosis necessary?, Am J Clin Nutr, 83, 1237, 10.1093/ajcn/83.6.1237
Brown, 2008, Selective versus total insulin resistance: A pathogenic paradox, Cell Metab, 7, 95, 10.1016/j.cmet.2007.12.009
Naïmi, 2007, Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes, Endocrinology, 148, 2424, 10.1210/en.2006-1411
Dong, 2008, Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation, Cell Metab, 8, 65, 10.1016/j.cmet.2008.06.006
Biddinger, 2008, Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis, Cell Metab, 7, 125, 10.1016/j.cmet.2007.11.013
Bizeau, 2005, Hepatic adaptations to sucrose and fructose, Metabolism, 54, 1189, 10.1016/j.metabol.2005.04.004
Di Rocco, 2008, Hepatocellular adenoma and metabolic balance in patients with type Ia glycogen storage disease, Mol Genet Metab, 93, 398, 10.1016/j.ymgme.2007.10.134
Glick, 1966, Effects of exercise on oxidative activities in rat liver mitochondria, Am J Physiol, 210, 1215, 10.1152/ajplegacy.1966.210.6.1215
Tonkonogi, 2002, Physical exercise and mitochondrial function in human skeletal muscle, Exerc Sport Sci Rev, 30, 129, 10.1097/00003677-200207000-00007
Palmieri, 2004, The mitochondrial transporter family (SLC25): Physiological and pathological implications, Pflugers Arch, 447, 689, 10.1007/s00424-003-1099-7
Bandsma, 2008, Increased de novo lipogenesis and delayed conversion of large VLDL into intermediate density lipoprotein particles contribute to hyperlipidemia in glycogen storage disease type 1a, Pediatr Res, 63, 702, 10.1203/PDR.0b013e31816c9013
Baraona, 2001, Gender differences in pharmacokinetics of alcohol, Alcohol Clin Exp Res, 25, 502, 10.1111/j.1530-0277.2001.tb02242.x
Farfán Labonne, 2009, Acetaldehyde-induced mitochondrial dysfunction sensitizes hepatocytes to oxidative damage, Cell Biol Toxicol, 25, 599, 10.1007/s10565-008-9115-5
Dey, 2006, Alcohol and oxidative liver injury, Hepatology, 43, S63, 10.1002/hep.20957
You, 2004, Molecular mechanisms of alcoholic fatty liver: Role of sterol regulatory element-binding proteins, Alcohol, 34, 39, 10.1016/j.alcohol.2004.07.004
Siler, 1999, De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption, Am J Clin Nutr, 70, 928, 10.1093/ajcn/70.5.928
McGarry, 1997, The mitochondrial carnitine palmitoyltransferase system, Eur J Biochem, 244, 1, 10.1111/j.1432-1033.1997.00001.x
Sozio, 2008, Alcohol and lipid metabolism, Am J Physiol Endocrinol Metab, 295, E10, 10.1152/ajpendo.00011.2008
Garcia-Villafranca, 2008, Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP activated protein kinase in rat liver, Biochimie, 90, 460, 10.1016/j.biochi.2007.09.019
Guzmán, 1990, Alterations in the regulatory properties of hepatic fatty acid oxidation and carnitine palmitoyltransferase I activity after ethanol feeding and withdrawal, Alcohol Clin Exp Res, 14, 472, 10.1111/j.1530-0277.1990.tb00506.x
Nanji, 2004, Alcoholic liver injury in the rat is associated with reduced expression of peroxisome proliferator-alpha (PPARalpha)-regulated genes and is ameliorated by PPARalpha activation, J Pharmacol Exp Ther, 310, 417, 10.1124/jpet.103.064717
Gambino, 2007, Polymorphism in microsomal triglyceride transfer protein: A link between liver disease and atherogenic postprandial lipid profile in NASH?, Hepatology, 45, 1097, 10.1002/hep.21631
Steinberg, 1991, Alcohol and atherosclerosis, Ann Intern Med, 114, 967, 10.7326/0003-4819-114-11-967
Suter, 2008, The effect of exercise, alcohol or both combined on health and physical performance, Int J Obes, 32, S48, 10.1038/ijo.2008.206
Schneider, 1976, Alteration of plasma lipids and intermediates of lipid metabolism in healthy fasting volunteers by ethanol and fructose, Res Exp Med, 167, 159, 10.1007/BF01851597
Yokoyama, 2007, Effects of excessive ethanol consumption on the diagnosis of the metabolic syndrome using its clinical diagnostic criteria, Intern Med, 46, 1345, 10.2169/internalmedicine.46.6196
Onishi, 2003, Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation, Biochem Biophys Res Comm, 303, 788, 10.1016/S0006-291X(03)00407-8
Lee, 2002, Temporal activation of p42/44 mitogen-activated protein kinase and c-Jun N-terminal kinase by acetaldehyde in rat hepatocytes and its loss after chronic ethanol exposure, J Pharmacol Exp Ther, 301, 908, 10.1124/jpet.301.3.908
Fiaschi, 1977, Fructose-induced hyperuricemia in essential hypertension, Metabolism, 26, 1219, 10.1016/0026-0495(77)90114-7
Taylor, 2008, Fructose consumption and the risk of kidney stones, Kidney Int, 73, 489, 10.1038/sj.ki.5002588
Nakagawa, 2006, Hypothesis: Fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome, Nat Clin Pract Nephrol, 1, 80, 10.1038/ncpneph0019
Johnson, 2009, Hypothesis: Could excessive fructose intake and uric acid cause type 2 diabetes?, Endocr Rev, 30, 96, 10.1210/er.2008-0033
Sánchez-Lozada, 2007, Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats, Am J Physiol Renal Physiol, 292, F423, 10.1152/ajprenal.00124.2006
Gao, 2007, Intake of added sugar and sugar-sweetened drink and serum uric acid concentration in US men and women, Hypertension, 50, 306, 10.1161/HYPERTENSIONAHA.107.091041
Nguyen, 2009, Sugar sweetened beverages, serum uric acid, and blood pressure in adolescents, J Pediatr, 154, 807, 10.1016/j.jpeds.2009.01.015
Savoca, 2004, The association of caffeinated beverages with blood pressure in adolescents, Arch Pediatr Adolesc Med, 158, 473, 10.1001/archpedi.158.5.473
Feig, 2008, Effects of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension, JAMA, 300, 924, 10.1001/jama.300.8.924
Bonsignore, 1962, A direct interconversion: D-fructose 6-phosphate to sedoheptulose 7-phosphate and D-xylulose 5-phosphate catalyzed by the enzymes transketolase and transaldolase, J Biol Chem, 237, 3597, 10.1016/S0021-9258(19)84494-0
Kabashima, 2003, Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver, Proc Natl Acad Sci U S A, 100, 5107, 10.1073/pnas.0730817100
Dentin, 2006, Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice, Diabetes, 55, 2159, 10.2337/db06-0200
Nagai, 2009, The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance, Cell Metab, 9, 252, 10.1016/j.cmet.2009.01.011
Shimomura, 1999, Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus, J Biol Chem, 274, 30028, 10.1074/jbc.274.42.30028
Araya, 2004, Increase in long-chain polyunsaturated fatty acid n- 6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease, Clin Sci (Lond), 106, 635, 10.1042/CS20030326
Donnelly, 2005, Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease, J Clin Invest, 115, 1343, 10.1172/JCI23621
Leitch, 1993, Measurement of human lipogenesis using deuterium incorporation, J Lipid Res, 34, 157, 10.1016/S0022-2275(20)41329-X
Hellerstein, 1991, Measurement of de novo hepatic lipogenesis in humans using stable isotopes, J Clin Invest, 87, 1841, 10.1172/JCI115206
Schwarz, 2003, Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets, Am J Clin Nutr, 77, 43, 10.1093/ajcn/77.1.43
Schwarz, 1995, Short-term alterations in carbohydrate energy intake in humans, J Clin Invest, 96, 2735, 10.1172/JCI118342
Aarsland, 1996, Contributions of de novo synthesis of fatty acids to total VLDL-triglyceride secretion during prolonged hyperglycemia/hyperinsulinemia in normal man, J Clin Invest, 98, 2008, 10.1172/JCI119005
Hudgins, 2000, Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects, J Lipid Res, 41, 595, 10.1016/S0022-2275(20)32407-X
Schwarz, 2009, Effects of short-term feeding with high- vs low- fructose isoenergetic diets on hepatic de novo lipogenesis, liver fat content and glucose regulation, Diabetes, 1476P
Faeh, 2005, Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men, Diabetes, 54, 1907, 10.2337/diabetes.54.7.1907
Stanhope, 2009, Consuming fructose-, not glucose-sweetened beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans, J Clin Invest, 119, 1322, 10.1172/JCI37385
Fried, 2003, Sugars, hypertriglyceridemia, and cardiovascular disease, Am J Clin Nutr, 78, 873S, 10.1093/ajcn/78.4.873S
Taghibiglou, 2002, Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose fed hamster model of insulin resistance, J Biol Chem, 277, 793, 10.1074/jbc.M106737200
Tsai, 2009, Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: Evidence for a link between hepatic inflammation and lipoprotein production, Am J Physiol Gastrointest Liver Physiol, 296, 1287, 10.1152/ajpgi.90540.2008
Hirano, 1989, Impaired very low-density lipoprotein-triglyceride catabolism in acute and chronic fructose-fed rats, Am J Physiol, 256, E559
Koo, 2008, Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver, Biochim Biophys Acta, 1782, 341, 10.1016/j.bbadis.2008.02.007
Roglans, 2007, Impairment of hepatic Stat-3 activation and reduction of PPARalpha activity in fructose-fed rats, Hepatology, 45, 778, 10.1002/hep.21499
Kelley, 2004, High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation, Endocrinology, 145, 548, 10.1210/en.2003-1167
Taghibiglou, 2000, Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance, J Biol Chem, 275, 8416, 10.1074/jbc.275.12.8416
Jurgens, 2005, Consuming fructose-sweetened beverages increases body adiposity in mice, Obes Res, 13, 1146, 10.1038/oby.2005.136
Teff, 2004, Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women, J Clin Endocrinol Metab, 89, 2963, 10.1210/jc.2003-031855
Chong, 2007, Mechanisms for the acute effect of fructose on postprandial lipemia, Am J Clin Nutr, 85, 1511, 10.1093/ajcn/85.6.1511
Teff, 2009, Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: Influence of insulin resistance on plasma triglyceride responses, J Clin Endocrinol Metab, 94, 1562, 10.1210/jc.2008-2192
Aeberli, 2007, Fructose intake is a predictor of LDL particle size in overweight schoolchildren, Am J Clin Nutr, 86, 1174, 10.1093/ajcn/86.4.1174
Hellerstein, 1996, Regulation of hepatic de novo lipogenesis in humans, Ann Rev Nutr, 16, 523, 10.1146/annurev.nu.16.070196.002515
Lê, 2009, Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes, Am J Clin Nutr, 89, 1760, 10.3945/ajcn.2008.27336
Zivkovic, 2007, Comparative review of diets for the metabolic syndrome: Implications for nonalcoholic fatty liver disease, Am J Clin Nutr, 86, 285, 10.1093/ajcn/86.2.285
Ackerman, 2005, Fructose-induced fatty liver disease: Hepatic effects of blood pressure and plasma triglyceride reduction, Hypertension, 45, 1012, 10.1161/01.HYP.0000164570.20420.67
Roden, 2006, Mechanisms of disease: Hepatic steatosis in type 2 diabetes-pathogenesis and clinical relevance, Nat Clin Pract Endo Metab, 2, 335, 10.1038/ncpendmet0190
Postic, 2008, Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice, J Clin Invest, 118, 829, 10.1172/JCI34275
Guzzaloni, 2000, Liver steatosis in juvenile obesity: Correlations with lipid profile, hepatic biochemical parameters and glycemic and insulinemic responses to an oral glucose tolerance test, Int J Obesity, 24, 772, 10.1038/sj.ijo.0801224
Valente, 2009, Association between sugar sweetened beverage consumption and serum alanine aminotransferase in obese children, Pediatr Acad Soc, 3854.45
Samuel, 2004, Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease, J Biol Chem, 279, 32345, 10.1074/jbc.M313478200
Wei, 2005, Fructose selectively modulates c-jun N-terminal kinase activity and insulin signaling in rat primary hepatocytes, J Nutr, 135, 1642, 10.1093/jn/135.7.1642
Hirosumi, 2002, A central role for JNK in obesity and insulin resistance, Nature, 420, 333, 10.1038/nature01137
Tuncman, 2006, Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance, Proc Natl Acad Sci U S A, 103, 10741, 10.1073/pnas.0603509103
Samuel, 2007, Inhibition of protein kinase C-epsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease, J Clin Invest, 117, 739, 10.1172/JCI30400
Wei, 2007, Fructose-mediated stress signaling in the liver: Implications for hepatic insulin resistance, J Nutr Biochem, 18, 1, 10.1016/j.jnutbio.2006.03.013
Kelley, 2004, High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation, Endocrinology, 145, 548, 10.1210/en.2003-1167
Bezerra, 2000, A high fructose diet affects the early steps of insulin action in muscle and liver of rats, J Nutr, 130, 1531, 10.1093/jn/130.6.1531
Melancon, 2006, Effects of high-sucrose feeding on insulin resistance and hemodynamic responses to insulin in spontaenously hypertensive rats, Am J Physiol Heart Circ Physiol, 290, 2571, 10.1152/ajpheart.01002.2005
Gonsolin, 2007, High dietary sucrose triggers hyperinsulinemia, increases myocardial ?-oxidation, reduces glycolytic flux, and delays post-ischemic contractile recovery, Mol Cell Biochem, 295, 217, 10.1007/s11010-006-9291-7
Michael, 2000, Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction, Mol Cell, 6, 87, 10.1016/S1097-2765(05)00015-8
D'Angelo, 2005, Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats, Hypertension, 46, 806, 10.1161/01.HYP.0000182697.39687.34
Sorensen, 2005, Effect of sucrose on inflammatory markers in overweight humans, Am J Clin Nutr, 82, 421, 10.1093/ajcn/82.2.421
Lê, 2006, A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans, Am J Clin Nutr, 84, 1374, 10.1093/ajcn/84.6.1374
Montell, 2001, DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells, Am J Physiol Endocrinol Metab, 280, E229, 10.1152/ajpendo.2001.280.2.E229
Krssak, 1999, Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: A 1H-NMR spectroscopy study, Diabetologia, 42, 113, 10.1007/s001250051123
Rajasekar, 2007, Effect of L-carnitine on skeletal muscle lipids and oxidative stress in rats fed high-fructose diet, Exp Diabetes Res, 2007, 72741, 10.1155/2007/72741
Sinha, 2002, Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: Relationships to insulin sensitivity, total body fat, and central adiposity, Diabetes, 51, 1022, 10.2337/diabetes.51.4.1022
Hesselink, 2004, Intramyocellular lipids and insulin sensitivity: Does size really matter?, Obesity Res, 12, 741, 10.1038/oby.2004.88
Kim, 2003, Primacy of hepatic insulin resistance in the development of the metabolic syndrome induced by an isocaloric moderate-fat diet in the dog, Diabetes, 52, 2453, 10.2337/diabetes.52.10.2453
Kabir, 2004, Molecular evidence supporting the portal theory: A causative link between visceral adiposity and hepatic insulin resistance, Am J Physiol Endocrinol Metab, 288, E454, 10.1152/ajpendo.00203.2004
Qu, 2007, PPAR? mediates the hypolipidemic action of fibrates by antagonizing FoxO1, Am J Physiol Endocrinol Metab, 292, E421, 10.1152/ajpendo.00157.2006
Poitout, 2008, Glucolipotoxicity: Fuel excess and beta-cell dysfunction, Endocr Rev, 29, 351, 10.1210/er.2007-0023
Cnop, 2008, An update on lipotoxic endoplasmic reticulum stress in pancreatic beta-cells, Biochem Soc Trans, 36, 909, 10.1042/BST0360909
Liu, 2007, Proinsulin maturation, misfolding, and proteotoxicity, Proc Natl Acad Sci U S A, 104, 15841, 10.1073/pnas.0702697104
Hotamisligil, 2008, Inflammation and endoplasmic reticulum stress in obesity and diabetes, Int J Obes, 32, S52, 10.1038/ijo.2008.238
Bergman, 2002, Accurate assessment of beta-cell function: The hyperbolic correction, Diabetes, 51, S212, 10.2337/diabetes.51.2007.S212
Lewis, 2004, Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglitazone, Diabetes, 53, 2893, 10.2337/diabetes.53.11.2893
Schulze, 2004, Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women, JAMA, 292, 927, 10.1001/jama.292.8.927
Montonen, 2007, Consumption of sweetened beverages and intakes of fructose and glucose predict type 2 diabetes occurrence, J Nutr, 137, 1447, 10.1093/jn/137.6.1447
Palmer, 2008, Sugar-sweetened beverages and incidence of type 2 diabetes mellitus in African American women, Arch Intern Med, 168, 1487, 10.1001/archinte.168.14.1487
Dills, 1993, Protein fructosylation: Fructose and the Maillard reaction, Am J Clin Nutr, 58, 779S, 10.1093/ajcn/58.5.779S
Figueroa-Romero, 2008, Mechanisms of disease: The oxidative stress theory of diabetic neuropathy, Rev Endocrinol Metab Dis, 9, 301, 10.1007/s11154-008-9104-2
Niemelä, 1995, Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease, Hepatology, 22, 1208, 10.1016/0270-9139(95)90630-4
Ahmed, 1992, Failure of common glycation assays to detect glycation by fructose, Clin Chem, 38, 1301, 10.1093/clinchem/38.7.1301
Schalkwijk, 2004, Fructose-mediated non-enzymatic glycation: Sweet coupling or bad modification, Diabetes Metab Res, 20, 369, 10.1002/dmrr.488
Bunn, 1981, Reaction of monosaccharides with proteins: Possible evolutionary significance, Science, 213, 222, 10.1126/science.12192669
Bose, 2008, Fructose-induced structural and functional modifications of hemoglobin: Implication for oxidative stress in diabetes mellitus, Biochim Biophys Acta, 1780, 800, 10.1016/j.bbagen.2008.02.001
Lee, 2009, Fructose and carbonyl metabolites and endogenous toxins, Chem Biol Interact, 178, 332, 10.1016/j.cbi.2008.10.011
Pickens, 2009, Dietary sucrose is essential to the development of liver injury in the MCD model of steatohepatitis, J Lipid Res, 50, 2072, 10.1194/jlr.M900022-JLR200
Assy, 2008, Soft drink consumption linked with fatty liver in the absence of traditional risk factors, Can J Gastroenterol, 22, 811, 10.1155/2008/810961
Abid, 2009, Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome, J Hepatol, 51, 918, 10.1016/j.jhep.2009.05.033
Kelley, 2002, Opioid modulation of taste hedonics within the ventral striatum, Physiol Behav, 76, 365, 10.1016/S0031-9384(02)00751-5
Carr, 2003, Evidence of increased dopamine receptor signaling in food-restricted rats, Neuroscience, 119, 1157, 10.1016/S0306-4522(03)00227-6
Wang, 2001, Brain dopamine and obesity, Lancet, 357, 354, 10.1016/S0140-6736(00)03643-6
Koob, 1998, Neurocircuitry targets in ethanol reward and dependence, Alcohol Clin Exp Res, 22, 3, 10.1111/j.1530-0277.1998.tb03611.x
Melis, 2009, Ethanol and acetaldehyde action on central dopamine systems: Mechanisms, modulation, and relationship to stress, Alcohol, 43, 531, 10.1016/j.alcohol.2009.05.004
Philpot, 2009, Repeated ethanol exposure during adolescence alters the developmental trajectory of dopaminergic output from the nucleus accumbens septi, Int J Dev Neurosci, 27, 805, 10.1016/j.ijdevneu.2009.08.009
Lind, 2009, Association between harmful alcohol consumption behavior and dopamine transporter (DAT1) gene polymorphisms in a male Finnish population, Psychiatr Genet, 19, 117, 10.1097/YPG.0b013e32832a4f7b
Heinz, 2009, Identifying the neural circuitry of alcohol craving and relapse vulnerability, Addict Biol, 14, 108, 10.1111/j.1369-1600.2008.00136.x
Tupala, 2004, Dopamine and alcoholism: Neurobiological basis of ethanol abuse, Prog Neuropsychopharmacol Biol Psychiatry, 28, 1221, 10.1016/j.pnpbp.2004.06.022
El-Haschimi, 2000, Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity, J Clin Invest, 105, 1827, 10.1172/JCI9842
Figlewicz, 2003, Adiposity signals and food reward: Expanding the CNS roles of insulin and leptin, Am J Physiol Regul Integr Comp Physiol, 284, R882, 10.1152/ajpregu.00602.2002
Farooqi, 2007, Leptin regulates striatal regions and human eating behavior, Science, 317, 1355, 10.1126/science.1144599
Shalev, 2001, Leptin attenuates food deprivation-induced relapse to heroin seeking, J Neurosci, 21, 121, 10.1523/JNEUROSCI.21-04-j0001.2001
Carvelli, 2002, PI3-kinase regulation of dopamine uptake, J Neurochem, 81, 859, 10.1046/j.1471-4159.2002.00892.x
Sipols, 2002, Intraventricular insulin decreases kappa opioid-mediated sucrose intake in rats, Peptides, 23, 2181, 10.1016/S0196-9781(02)00246-2
Anderzhanova, 2007, Altered basal and stimulated accumbens dopamine release in obese OLETF rats as a function of age and diabetic status, Am J Physiol Regul Integr Comp Physiol, 293, R603, 10.1152/ajpregu.00301.2007
Kellerer, 2001, Insulin inhibits leptin receptor signalling in HEK293 cells at the level of janus kinase-2: A potential mechanism for hyperinsulinaemia-associated leptin resistance, Diabetologia, 44, 1125, 10.1007/s001250100614
Hill, 2008, Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice, J Clin Invest, 118, 1796, 10.1172/JCI32964
Han, 2008, Insulin resistance, hyperinsulinemia, and energy intake in overweight children, J Pediatr, 152, 612, 10.1016/j.jpeds.2007.12.036
Lustig, 2006, Childhood obesity: Behavioral aberration or biochemical drive?, Nat Clin Pract Endocrinol Metab, 2, 447, 10.1038/ncpendmet0220
Brüning, 2000, Role of brain insulin receptor in control of body weight and reproduction, Science, 289, 2122, 10.1126/science.289.5487.2122
Banks, 2004, Triglycerides induce leptin resistance at the blood-brain barrier, Diabetes, 53, 1253, 10.2337/diabetes.53.5.1253
Druce, 2006, Subcutaneous administration of ghrelin stimulates energy intake in healthy lean human volunteers, Int J Obes, 30, 293, 10.1038/sj.ijo.0803158
Kamegai, 2000, Central effect of ghrelin, an endogenous growth hormone secretagogue, on hypothalamic peptide gene expression, Endocrinology, 141, 4797, 10.1210/endo.141.12.7920
Tschöp, 2000, Ghrelin induces adiposity in rodents, Nature, 407, 908, 10.1038/35038090
Cummings, 2001, A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans, Diabetes, 50, 1714, 10.2337/diabetes.50.8.1714
Lindqvist, 2008, Effects of sucrose, glucose and fructose on peripheral and central appetite signals, Regul Pept, 150, 26, 10.1016/j.regpep.2008.06.008
Cha, 2008, Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake, Proc Natl Acad Sci U S A, 105, 16871, 10.1073/pnas.0809255105
Lane, 2009, Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain, Biochem Biophys Res Comm, 382, 1, 10.1016/j.bbrc.2009.02.145
Erlanson-Albertsson, 2005, How palatable food disrupts appetite regulation, Basic Clin Pharmacol Toxicol, 97, 61, 10.1111/j.1742-7843.2005.pto_179.x
Pelchat, 2002, Of human bondage: Food craving, obsession, compulsion, and addiction, Physiol Behav, 76, 347, 10.1016/S0031-9384(02)00757-6
Spangler, 2004, Opiate-like effects of sugar on gene expression in reward areas of the rat brain, Mol Brain Res, 124, 134, 10.1016/j.molbrainres.2004.02.013
Pelchat, 2004, Images of desire: Food-craving activation during fMRI, Neuroimage, 23, 1486, 10.1016/j.neuroimage.2004.08.023
Avena, 2008, Evidence for sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake, Neurosci Biobehav Rev, 32, 20, 10.1016/j.neubiorev.2007.04.019
Casswell, 2009, Reducing harm from alcohol: Call to action, Lancet, 373, 2247, 10.1016/S0140-6736(09)60745-5
Cannon, 2004, Why the Bush administration and the global sugar industry are determined to demolish the 2004 WHO global strategy on diet, physical activity and health, Public Health Nutr, 7, 369, 10.1079/PHN2004625
Bleich, 2009, Increasing consumption of sugar-sweetened beverages among US adults: 1988-1994 to 1999-2004, Am J Clin Nutr, 89, 372, 10.3945/ajcn.2008.26883
Keyes, 2008, Socio-economic status and problem alcohol use: The positive relationship between income and the DSM-IV alcohol abuse diagnosis, Addiction, 103, 1120, 10.1111/j.1360-0443.2008.02218.x
Puhl, 2010, Obesity stigma: Important considerations for public health, Am J Public Health, 100, 1019, 10.2105/AJPH.2009.159491
Mulia, 2009, Disparities in alcohol-related problems among white, black, and Hispanic Americans, Alcohol Clin Exp Res, 33, 654, 10.1111/j.1530-0277.2008.00880.x
Burelle, 2006, Comparison of exogenous glucose, fructose and galactose oxidation during exercise using 13C-labelling, Br J Nutr, 96, 56, 10.1079/BJN20061799
Fung, 2009, Sweetened beverage consumption and risk of coronary heart disease in women, Am J Clin Nutr, 89, 1037, 10.3945/ajcn.2008.27140
Ropelle, 2009, Acute exercise modulates the Foxo1/PGC-1alpha pathway in the liver of diet-induced obesity rats, J Physiol, 587, 2069, 10.1113/jphysiol.2008.164202
Liese, 2005, Dietary glycemic index and glycemic load, carbohydrate and fiber intake, and measures of insulin sensitivity, secretion, and adiposity in the Insulin Resistance Atherosclerosis Study, Diabetes Care, 28, 2832, 10.2337/diacare.28.12.2832
Martlett, 2002, Position of the American Dietetic Association: Health implications of dietary fiber, J Am Diet Assoc, 102, 993, 10.1016/S0002-8223(02)90228-2
Pereira, 2001, Dietary fiber and body weight regulation, Pediatr Clin North Am, 48, 969, 10.1016/S0031-3955(05)70351-5
1991
Lim, 2010, Role of fructose in the pathogenesis of NAFLD and the metabolic syndrome, Nat Rev Gastroenterol Hepatol, 7, 251, 10.1038/nrgastro.2010.41