RFXB and its splice variant RFXBSV mediate the antagonism between IFNγ and TGFβ on COL1A2 transcription in vascular smooth muscle cells

Hansson, 2006, The immune response in atherosclerosis: a double-edged sword, Nat. Rev. Immunol., 6, 508, 10.1038/nri1882

Katsuda, 2003, Atherosclerosis and extracellular matrix, J. Atheroscler. Thromb., 10, 267, 10.5551/jat.10.267

Libby, 2000, Changing concepts of atherogenesis, J. Intern. Med., 247, 349, 10.1046/j.1365-2796.2000.00654.x

Rekhter, 1993, Type I collagen gene expression in human atherosclerosis. Localization to specific plaque regions, Am. J. Pathol., 143, 1634

Warner, 1989, Immune interferon inhibits proliferation and induces 2′-5′-oligoadenylate synthetase gene expression in human vascular smooth muscle cells, J. Clin. Invest., 83, 1174, 10.1172/JCI113998

Frostegard, 1999, Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines, Atherosclerosis, 145, 33, 10.1016/S0021-9150(99)00011-8

Harvey, 2005, Interferon-gamma and atherosclerosis: pro- or anti-atherogenic?, Cardiovasc. Res., 67, 11, 10.1016/j.cardiores.2005.04.019

Feinberg, 2005, Role of transforming growth factor-beta1/Smads in regulating vascular inflammation and atherogenesis, Panminerva Med., 47, 169

Robertson, 2003, Disruption of TGF-beta signaling in T cells accelerates atherosclerosis, J. Clin. Invest., 112, 1342, 10.1172/JCI18607

Roberts, 1986, Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro, Proc. Natl Acad. Sci. USA, 83, 4167, 10.1073/pnas.83.12.4167

Rosenbloom, 1984, Transcriptional control of human diploid fibroblast collagen synthesis by gamma-interferon, Biochem. Biophys. Res. Commun., 123, 365, 10.1016/0006-291X(84)90422-4

Higashi, 2003, Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3, J. Biol. Chem., 278, 43470, 10.1074/jbc.M302339200

Dooley, 2006, Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects, J. Biol. Chem., 281, 1784, 10.1074/jbc.M510215200

Eickelberg, 2001, Molecular mechanisms of TGF-(beta) antagonism by interferon (gamma) and cyclosporine A in lung fibroblasts, FASEB J., 15, 797, 10.1096/fj.00-0233com

Ghosh, 2001, Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactivators, J. Biol. Chem., 276, 11041, 10.1074/jbc.M004709200

Tredget, 2000, Transforming growth factor-beta mRNA and protein in hypertrophic scar tissues and fibroblasts: antagonism by IFN-alpha and IFN-gamma in vitro and in vivo, J. Interferon Cytokine Res., 20, 143, 10.1089/107999000312540

Rishikof, 2004, Phenylbutyrate decreases type I collagen production in human lung fibroblasts, J. Cell Biochem., 91, 740, 10.1002/jcb.10742

Guenette, 1992, DNA methylation inhibits transcription of procollagen alpha 2(I) promoters, Biochem. J., 283, 699, 10.1042/bj2830699

Xu, 2003, Interferon gamma repression of collagen (COL1A2) transcription is mediated by the RFX5 complex, J. Biol. Chem., 278, 49134, 10.1074/jbc.M309003200

Xu, 2006, Regulatory factor for X-box family proteins differentially interact with histone deacetylases to repress collagen alpha2(I) gene (COL1A2) expression, J. Biol. Chem., 281, 9260, 10.1074/jbc.M511724200

Goldberg, 1992, Tissue-specific expression of the mouse alpha 2(I) collagen promoter. Studies in transgenic mice and in tissue culture cells, J. Biol. Chem., 267, 19622, 10.1016/S0021-9258(18)41820-0

Zhu, 2001, A 36-amino-acid region of CIITA is an effective inhibitor of CBP: novel mechanism of gamma interferon-mediated suppression of collagen alpha(2)(I) and other promoters, Mol. Cell Biol., 21, 7078, 10.1128/MCB.21.20.7078-7088.2001

Sengupta, 2005, Collagen alpha1(I) gene (COL1A1) is repressed by RFX family, J. Biol. Chem., 280, 21004, 10.1074/jbc.M413191200

Zhu, 2000, Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter, Mol. Cell Biol., 20, 6051, 10.1128/MCB.20.16.6051-6061.2000

Tsai, 2002, Regulation of histone deacetylase 2 by protein kinase CK2, J. Biol. Chem., 277, 31826, 10.1074/jbc.M204149200

Nagarajan, 1999, RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency, Immunity, 10, 153, 10.1016/S1074-7613(00)80016-3

Xu, 2004, Major histocompatibility class II transactivator (CIITA) mediates repression of collagen (COL1A2) transcription by interferon gamma (IFN-gamma), J. Biol. Chem., 279, 41319, 10.1074/jbc.M404174200

Sengupta, 2002, The RFX family interacts at the collagen (COL1A2) start site and represses transcription, J. Biol. Chem., 277, 24926, 10.1074/jbc.M111712200

Sobral, 2007, Opposite effects of TGF-beta1 and IFN-gamma on transdifferentiation of myofibroblast in human gingival cell cultures, J. Clin. Periodontol., 34, 397, 10.1111/j.1600-051X.2007.01063.x

Gu, 2004, Effect of IFN-gamma and dexamethasone on TGF-beta1-induced human fetal lung fibroblast-myofibroblast differentiation, Acta. Pharmacol. Sin., 25, 1479

Das, 2002, Differential splicing generates Tvl-1/RFXANK isoforms with different functions, J. Biol. Chem., 277, 45172, 10.1074/jbc.M204117200

Zika, 2003, Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation, Mol. Cell Biol., 23, 3091, 10.1128/MCB.23.9.3091-3102.2003

Kook, 2003, Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop, J. Clin. Invest., 112, 863, 10.1172/JCI19137

Velican, 1969, Relationship between regional aortic susceptibility to atherosclerosis and macromolecular structural stability, J. Atheroscler. Res., 9, 193, 10.1016/S0368-1319(69)80054-2

Amento, 1991, Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells, Arterioscler Thromb, 11, 1223, 10.1161/01.ATV.11.5.1223

Hall, 2006, Molecular anatomy of a speckle, Anat. Rec. A Discov. Mol. Cell Evol. Biol., 288, 664, 10.1002/ar.a.20336

Misteli, 2007, Beyond the sequence: cellular organization of genome function, Cell, 128, 787, 10.1016/j.cell.2007.01.028

Bridoux, 1997, Transforming growth factor beta (TGF-beta)-dependent inhibition of T helper cell 2 (Th2)-induced autoimmunity by self-major histocompatibility complex (MHC) class II-specific, regulatory CD4(+) T cell lines, J. Exp. Med., 185, 1769, 10.1084/jem.185.10.1769

Nandan, 1997, TGF-beta attenuates the class II transactivator and reveals an accessory pathway of IFN-gamma action, J. Immunol., 158, 1095, 10.4049/jimmunol.158.3.1095

Panek, 1995, TGF-beta suppression of IFN-gamma-induced class II MHC gene expression does not involve inhibition of phosphorylation of JAK1, JAK2, or signal transducers and activators of transcription, or modification of IFN-gamma enhanced factor X expression, J. Immunol., 154, 610, 10.4049/jimmunol.154.2.610

Cunha, 2008, Exon organization and novel alternative splicing of the human ANK2 gene: implications for cardiac function and human cardiac disease, J. Mol. Cell Cardiol., 45, 724, 10.1016/j.yjmcc.2008.08.005