Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
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Fyles, 2006, Long-term performance of intestinal fluid pressure and hypoxia as prognostic factors in cervix cancer, Radiother Oncol, 80, 132, 10.1016/j.radonc.2006.07.014
Nordsmark, 2005, Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study, Radiother Oncol, 77, 18, 10.1016/j.radonc.2005.06.038
Nordsmark, 2006, The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study, Radiother Oncol, 80, 123, 10.1016/j.radonc.2006.07.010
Durand, 2001, Clinical relevance of intermittent tumour blood flow, Acta Oncol, 40, 929, 10.1080/02841860152708206
Brown, 1979, Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation, Br J Radiol, 52, 650, 10.1259/0007-1285-52-620-650
Dewhirst, 2007, Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting, Cancer Res, 67, 854, 10.1158/0008-5472.CAN-06-4744
Dewhirst, 1998, Temporal changes in PO2 of R3230AC tumors in Fischer-344 rats, Int J Radiat Oncol Biol Phys, 42, 723, 10.1016/S0360-3016(98)00304-6
Chaplin, 1987, Intermittent blood flow in a murine tumor: radiobiological effects, Cancer Res, 47, 597
Dewhirst, 2008, Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response, Nat Rev Cancer, 8, 425, 10.1038/nrc2397
Toffoli, 2008, Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours, FEBS J, 275, 2991, 10.1111/j.1742-4658.2008.06454.x
Mizushima, 2005, The pleiotropic role of autophagy: from protein metabolism to bactericide, Cell Death Differ, 12, 1535, 10.1038/sj.cdd.4401728
Tanida, 2004, LC3 conjugation system in mammalian autophagy, Int J Biochem Cell Biol, 36, 2503, 10.1016/j.biocel.2004.05.009
Kuma, 2004, The role of autophagy during the early neonatal starvation period, Nature, 432, 1032, 10.1038/nature03029
Mizushima, 2002, Autophagosome formation in mammalian cells, Cell Struct Funct, 27, 421, 10.1247/csf.27.421
Klionsky, 2008, Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes, Autophagy, 4, 151, 10.4161/auto.5338
Boya, 2005, Inhibition of macroautophagy triggers apoptosis, Mol Cell Biol, 25, 1025, 10.1128/MCB.25.3.1025-1040.2005
Yamamoto, 1998, Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells, Cell Struct Funct, 23, 33, 10.1247/csf.23.33
Klionsky, 2000, Autophagy as a regulated pathway of cellular degradation, Science, 290, 1717, 10.1126/science.290.5497.1717
Tan, 2008, Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases, Hum Mol Genet, 17, 431, 10.1093/hmg/ddm320
Mukhopadhyay, 2007, Proteasome-independent functions of ubiquitin in endocytosis and signaling, Science, 315, 201, 10.1126/science.1127085
Zhang, 2008, Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia, J Biol Chem, 283, 10892, 10.1074/jbc.M800102200
Chiu, 2006, Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations, PLoS Genet, 2, e116, 10.1371/journal.pgen.0020116
Koritzinsky, 2007, Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia, Radiother Oncol, 83, 353, 10.1016/j.radonc.2007.04.031
Li, 2002, Reactive species mechanisms of cellular hypoxia-reoxygenation injury, Am J Physiol Cell Physiol, 282, C227, 10.1152/ajpcell.00112.2001
Wouters, 2004, Targeting hypoxia tolerance in cancer, Drug Resist Updat, 7, 25, 10.1016/j.drup.2003.12.004
Deffieu, 2009, Glutathione participates in the regulation of mitophagy in yeast, J Biol Chem, 284, 14828, 10.1074/jbc.M109.005181
Kim, 2008, A critical role of superoxide anion in selenite-induced mitophagic cell death, Autophagy, 4, 76, 10.4161/auto.5119
Lum, 2005, Autophagy in metazoans: cell survival in the land of plenty, Nat Rev Mol Cell Biol, 6, 439, 10.1038/nrm1660
Wouters, 2008, Hypoxia signalling through mTOR and the unfolded protein response in cancer, Nat Rev Cancer, 10.1038/nrc2501
Pursiheimo, 2009, Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62, Oncogene, 28, 334, 10.1038/onc.2008.392
Karantza-Wadsworth, 2007, Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis, Genes Dev, 21, 1621, 10.1101/gad.1565707