Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a

Molecular Immunology - Tập 63 - Trang 456-463 - 2015
E. Arduin1, S. Arora1, P.R. Bamert2, T. Kuiper2, S. Popp1, S. Geisse1, R. Grau2, T. Calzascia1, G. Zenke1, J. Kovarik1
1Novartis Institutes for Biomedical Research, Novartis Campus, CH-4056 Basel, Switzerland
2Novartis Pharma AG, Novartis Campus, CH-4056 Basel, Switzerland

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