The one-two punch: TIM-3 blockade targets immune and tumor cells to knock out pediatric brain tumors

Cancer Cell - Tập 41 - Trang 1843-1845 - 2023
Juyeun Lee1, Justin D. Lathia1,2,3
1Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA
2Case Comprehensive Cancer Center, Cleveland, OH, USA
3Rose Ella Burkhardt Brain Tumor Center, Cleveland Clinic, Cleveland, OH, USA

Tài liệu tham khảo

Pachocki, 2022, Current perspectives on diffuse midline glioma and a different role for the immune microenvironment compared to glioblastoma, J. Neuroinflammation, 19, 276, 10.1186/s12974-022-02630-8 Hwang, 2018, IMMU-09. Outcome of patients with recurrent diffuse intrinsic pontine glioma (DIPG) treated with pembrolizumab (anti-PD-1): A pediatric brain tumor consortium study (PBTC045), Neuro Oncol., 20, i100, 10.1093/neuonc/noy059.325 Persson, 2022, The intrinsic and microenvironmental features of diffuse midline glioma: Implications for the development of effective immunotherapeutic treatment strategies, Neuro Oncol., 24, 1408, 10.1093/neuonc/noac117 Ausejo-Mauleon, 2023, TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory, Cancer Cell, 41, 1911, 10.1016/j.ccell.2023.09.001 Wolf, 2020, TIM3 comes of age as an inhibitory receptor, Nat. Rev. Immunol., 20, 173, 10.1038/s41577-019-0224-6 Qin, 2020, Prognostic Values of TIM-3 Expression in Patients With Solid Tumors: A Meta-Analysis and Database Evaluation, Front. Oncol., 10, 1288, 10.3389/fonc.2020.01288 Krysko, 2012, Immunogenic cell death and DAMPs in cancer therapy, Nat. Rev. Cancer, 12, 860, 10.1038/nrc3380 Xie, 2022, Research progress in inducing immunogenic cell death of tumor cells, Front. Immunol., 13, 10.3389/fimmu.2022.1017400 Baek, 2022, Clinical Intervention Using Focused Ultrasound (FUS) Stimulation of the Brain in Diverse Neurological Disorders, Front. Neurol., 13, 10.3389/fneur.2022.880814