Alterations in Expression of p11 and SERT in Mucosal Biopsy Specimens of Patients With Irritable Bowel Syndrome

Dunlop, 2005, Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome, Clin Gastroenterol Hepatol, 3, 349, 10.1016/S1542-3565(04)00726-8 Atkinson, 2006, Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome, Gastroenterology, 130, 34, 10.1053/j.gastro.2005.09.031 Lesch, 1996, Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region, Science, 274, 1527, 10.1126/science.274.5292.1527 Coates, 2004, Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome, Gastroenterology, 126, 1657, 10.1053/j.gastro.2004.03.013 Camilleri, 2002, Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome, Gastroenterology, 123, 425, 10.1053/gast.2002.34780 Maroteaux, 1992, Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers, Proc Natl Acad Sci U S A, 89, 3020, 10.1073/pnas.89.7.3020 Moret, 2000, The possible role of 5-HT(1B/D) receptors in psychiatric disorders and their potential as a target for therapy, Eur J Pharmacol, 404, 1, 10.1016/S0014-2999(00)00581-1 Coulie, 1997, Sumatriptan, a selective 5-HT1 receptor agonist, induces a lag phase for gastric emptying of liquids in humans, Am J Physiol, 272, G902 Boeckxstaens, 2002, The proximal stomach and postprandial symptoms in functional dyspeptics, Am J Gastroenterol, 97, 40, 10.1111/j.1572-0241.2002.05421.x Tack, 2004, Role of tension receptors in dyspeptic patients with hypersensitivity to gastric distention, Gastroenterology, 127, 1058, 10.1053/j.gastro.2004.07.005 Svenningsson, 2006, Alterations in 5-HT1B receptor function by p11 in depression-like states, Science, 311, 77, 10.1126/science.1117571 Deora, 2004, An annexin 2 phosphorylation switch mediates p11-dependent translocation of annexin 2 to the cell surface, J Biol Chem, 279, 43411, 10.1074/jbc.M408078200 Okuse, 2002, Annexin II light chain regulates sensory neuron-specific sodium channel expression, Nature, 417, 653, 10.1038/nature00781 van de Graaf, 2003, Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex, EMBO J, 22, 1478, 10.1093/emboj/cdg162 Girard, 2002, p11, An annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1, EMBO J, 21, 4439, 10.1093/emboj/cdf469 Daub, 2003, Expression of members of the S100 Ca2+-binding protein family in guinea-pig smooth muscle, Cell Calcium, 33, 1, 10.1016/S0143-4160(02)00167-7 Zimmer, 2005, S100-mediated signal transduction in the nervous system and neurological diseases, Cell Mol Biol, 51, 201 Talley, 1990, Assessment of functional gastrointestinal disease: the bowel disease questionnaire, Mayo Clin Proc, 65, 1456, 10.1016/S0025-6196(12)62169-7 Thompson, 1999, Functional bowel disorders and functional abdominal pain, Gut, 45, II43, 10.1136/gut.45.2008.ii43 Livak KJ. ABI Prism 7700 Sequence Detection System, user bulletin 2, PE Applied Biosystems, 1997. Kim, 2004, Association of distinct α(2) adrenoceptor and serotonin transporter polymorphisms with constipation and somatic symptoms in functional gastrointestinal disorders, Gut, 53, 829, 10.1136/gut.2003.030882 Jenkins, 1997, Guidelines for the initial biopsy diagnosis of suspected chronic idiopathic inflammatory bowel disease, J Clin Pathol, 50, 93, 10.1136/jcp.50.2.93 Sharp, 2006, Neuroscience, Science, 311, 45, 10.1126/science.1122819 Caspi, 2003, Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene, Science, 301, 386, 10.1126/science.1083968 Hariri, 2002, Serotonin transporter genetic variation and the response of the human amygdala, Science, 297, 400, 10.1126/science.1071829 Sibille, 2006, SERT-ainly involved in depression, but when?, Am J Psychiatry, 163, 8, 10.1176/appi.ajp.163.1.8 Donier, 2005, Annexin II light chain p11 promotes functional expression of acid-sensing ion channel ASIC1a, J Biol Chem, 280, 38666, 10.1074/jbc.M505981200 Cervero, 2004, Understanding the signaling and transmission of visceral nociceptive events, J Neurobiol, 61, 45, 10.1002/neu.20084 Quartero, 2005, Bulking agents, antispasmodic and antidepressant medication for the treatment of irritable bowel syndrome, Cochrane Database Syst Rev, 2, 10.1002/14651858.CD003460.pub2