Immunology of cancer stem cells in solid tumours. A review

European Journal of Cancer - Tập 50 - Trang 649-655 - 2014
Cristina Maccalli1, Andrea Volontè1, Carolina Cimminiello1, Giorgio Parmiani1
1Unit of Immuno-Biotherapy of Melanoma and Solid Tumors, Division of Molecular Oncology, San Raffaele Scientific Institute, Milan, Italy

Tài liệu tham khảo

Vezzoni, 2008, Limitations of the cancer stem cell theory, Cytotechnology, 10.1007/s10616-008-9166-8 Ricci-Vitiani, 2009, Colon cancer stem cells, J Mol Med, 87, 1097, 10.1007/s00109-009-0518-4 Clevers, 2011, The cancer stem cell: premises, promises and challenges, Nat Med, 17, 313, 10.1038/nm.2304 Maugeri-Saccà, 2011, Cancer stem cells and chemosensitivity, Clin Cancer Res, 17, 4942, 10.1158/1078-0432.CCR-10-2538 Dirck, 2008, Stem cell concepts renew cancer research, Blood, 112, 4793, 10.1182/blood-2008-08-077941 Lu, 2012, Fra-1 promotes breast cancer chemosensitivity by driving cancer stem cells from dormancy, Cancer Res, 72, 3451, 10.1158/0008-5472.CAN-11-2536 Li, 2011, Stem cell quiescence, Clin Cancer Res, 17, 4936, 10.1158/1078-0432.CCR-10-1499 Francipane, 2008, Crucial role of interleukin-4 in the survival of colon cancer stem cells, Cancer Res, 68, 4022, 10.1158/0008-5472.CAN-07-6874 Bao, 2008, Targeting cancer stem cells through L1CAM suppresses glioma growth, Cancer Res, 68, 6043, 10.1158/0008-5472.CAN-08-1079 Dihen, 2006, Cancer stem cells and radiotherapy: new insights into tumor radioresistance, J Natl Cancer Inst, 98, 1755, 10.1093/jnci/djj505 Irvin, 2010, T cells enhance stem-like properties and conditional malignancy in gliomas, PLoS One, 5, e10974, 10.1371/journal.pone.0010974 Elleback, 2012, Immunotherapy for metastatic colorectal cancer: present status and new options, Scand J Gastroenterol, 47, 315, 10.3109/00365521.2012.640831 Kalluri, 2009, The basics for epithelial–mesenchymal transition, J Clin Invest, 119, 1420, 10.1172/JCI39104 Magee, 2012, Cancer stem cells: impact, heterogeneity and uncertainty, Cancer Cell, 21, 283, 10.1016/j.ccr.2012.03.003 Lapidot, 1994, A cell initiating human myeloid leukemia after transplantation into SCID mice, Nature, 367, 645, 10.1038/367645a0 Bonnet, 1997, Human acute myeloid leukemia is organized as hierarchy that originates from a primitive hematopoietic cell, Nat Med, 3, 730, 10.1038/nm0797-730 Du, 2011, Overexpression of IL-3Ralpha on CD34+CD38− stem cells defines leukemia-initiating cells in Fanconi anemia AML, Blood, 117, 4243, 10.1182/blood-2010-09-309179 Huang, 2009, Aldehyde dehydrogenase 1 is a marker for normal and malignant human colon stem cells (SC) and tracks SC overpopulation during colon tumorigenesis, Cancer Res, 69, 3382, 10.1158/0008-5472.CAN-08-4418 Gerber, 2012, A clinically relevant population of leukemic CD34(+)CD38(−) cells in acute myeloid leukemia, Blood, 119, 3571, 10.1182/blood-2011-06-364182 Cho, 2008, Recent advances in cancer stem cells, Curr Opin Genet Dev, 18, 48, 10.1016/j.gde.2008.01.017 Wakamatsu, 2012, Expression of cancer stem cell markers ALDH1, CD44, and CD133 in primary tumor and lymph node metastasis of gastric cancer, Pathol Int, 62, 112, 10.1111/j.1440-1827.2011.02760.x Luo, 2012, ALDH1Aisozymes are markers of human melanoma stem cells and potential therapeutic targets, Stem cells, 30, 2100, 10.1002/stem.1193 Singh, 2004, Identification of human brain tumor initiating cells, Nature, 432, 396, 10.1038/nature03128 Schneider, 2012, Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker, BMC Cancer, 12, 96, 10.1186/1471-2407-12-96 Hermann, 2007, Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cells, Cell Stem Cells, 1, 313, 10.1016/j.stem.2007.06.002 Tirino, 2009, The role of CD133 in the identification and characterisation of tumor-initiating cells in non-small-cell lung cancer, Eur J Cardiothorac Surg, 36, 446, 10.1016/j.ejcts.2009.03.063 Curley, 2009, CD133 expression defines a tumor initiating cell population in primary human ovarian cancer, Stem Cells, 27, 2875, 10.1002/stem.236 Collins, 2005, Prospective identification of tumorigenic prostate cancer stem cells, Cancer Res, 65, 10946, 10.1158/0008-5472.CAN-05-2018 Chen, 2012, CD133(+)EpCAM(+) phenotype possesses more characteristics of tumor initiating cells in hepatocellular carcinoma Huh7 cells, Int J Biol Sci, 8, 992, 10.7150/ijbs.4454 Dalerba, 2008, Phenotypic characterization of human colorectal cancer stem cells, Proc Natl Acad Sci U S A, 104, 10158, 10.1073/pnas.0703478104 Li, 2007, Identification of pancreatic stem cells, Cancer Res, 67, 1030, 10.1158/0008-5472.CAN-06-2030 Saini, 2012, Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma, PLoS One, 7, e41401, 10.1371/journal.pone.0041401 Kemper, 2010, The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation, Cancer Res, 70, 719, 10.1158/0008-5472.CAN-09-1820 Al Hajj, 2003, Prospective identification of tumorigenic breast cancer cells, Proc Natl Acad Sci U S A, 100, 3983, 10.1073/pnas.0530291100 Schatton, 2008, Identification of cells initiating human melanomas, Nature, 451, 345, 10.1038/nature06489 Du, 2008, CD44 is of functional importance for colorectal cancer stem cells, Clin Cancer Res, 14, 6751, 10.1158/1078-0432.CCR-08-1034 Clay, 2010, Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde hydrogenase, Head Neck, 32, 1195, 10.1002/hed.21315 Choi, 2009, Cancer stem cell markers CD133 and CD24correlate with invasiveness and differentiation in colorectal adenocarcinoma, World J Gastroenterol, 15, 2258, 10.3748/wjg.15.2258 Zhang, 2012, Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis, Cell, 148, 259, 10.1016/j.cell.2011.11.050 Wang, 2012, ALDH1-bright epithelial ovarian cancer cells are associated with CD44 expression, drug resistance, and poor clinical outcome, Am J Pathol, 180, 1159, 10.1016/j.ajpath.2011.11.015 Yang, 2008, Significance of CD90+ cancer stem cells in human liver cancer, Cancer Cells, 13, 153, 10.1016/j.ccr.2008.01.013 Kong, 2008, CD34+CD38+CD19+ as well as CD34+CD38−CD19+ cells are leukemia-initiating cells with self-renewed capacity in human B-precursor ALL, Leukemia, 22, 1207, 10.1038/leu.2008.83 Nishizawa, 2012, HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells, Cancer Res, 2012, 2844, 10.1158/0008-5472.CAN-11-3062 Li, 2012, Cancer stem cells: distinct entities or dynamically regulated phenotypes?, Cancer Res, 72, 576, 10.1158/0008-5472.CAN-11-3070 Rosen, 2009, The increasing complexity of the cancer stem cell paradigm, Science, 324, 1670, 10.1126/science.1171837 Takeda, 2011, Interconversion between intestinal stem cell populations in distinct niches, Science, 334, 1420, 10.1126/science.1213214 Roesch, 2010, A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth, Cell, 141, 583, 10.1016/j.cell.2010.04.020 Kim, 2013, Aptamer identification of brain tumor-initiating cells, Cancer Res, 73, 4923, 10.1158/0008-5472.CAN-12-4556 Tu, 2013, MicroRNA-218 inhibits glioma invasion, migration, proliferation, and cancer stem-like cell self-renewal by targeting the polycomb group gene Bmi1, Cancer Res, 73, 6046, 10.1158/0008-5472.CAN-13-0358 Mani, 2008, The epithelial–mesenchymal transition generates cells with properties of stem cells, Cell, 133, 704, 10.1016/j.cell.2008.03.027 Podberezin, 2012, Cancer stem cells: a review of potential clinical applications, Arch Pathol Lab Med Li, 2011, C-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype, Proc Natl Acad Scie U S A, 108, 9951, 10.1073/pnas.1016912108 Hjelmeland, 2012, The quest for self-identity: not all cancer stem cells are the same, Clin Cancer Res, 18, 3495, 10.1158/1078-0432.CCR-12-1456 Zorniak, 2012, Differential expression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase and neural lineage markers correlate with glioblastoma xenograft infiltration and patient survival, Clin Cancer Res, 18, 3628, 10.1158/1078-0432.CCR-12-0339 Di Tomaso, 2010, Immunobiological characterization of cancer stem cells isolated from glioblastoma patients, Clin Cancer Res, 16, 800, 10.1158/1078-0432.CCR-09-2730 Schatton, 2010, Modulation of T-cell activation by malignant melanoma initiating cells, Cancer Res, 70, 697, 10.1158/0008-5472.CAN-09-1592 Wei, 2010, Glioma-associated cancer-initiating cells induce immunosuppression, Clin Cancer Res, 16, 461, 10.1158/1078-0432.CCR-09-1983 Lottaz, 2010, Transcriptional profiles of CD133+ and CD133− glioblastoma-derived cancer stem cell lines suggest different cells of origin, Cancer Res, 70, 2030, 10.1158/0008-5472.CAN-09-1707 Le Blanc, 2003, Expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells, Exp Hematol, 31, 890, 10.1016/S0301-472X(03)00110-3 Schatton, 2009, Antitumor immunity and cancer stem cells, Ann N Y Acad Sci, 1176, 154, 10.1111/j.1749-6632.2009.04568.x Kim, 2009, Soluble mediators from human neural stem cells play a critical role in suppression of T-cell activation and proliferation, J Neurosci Res, 87, 2264, 10.1002/jnr.22050 Tsuyada, 2012, CCL-2-Mediates cross-talk between cancer cells and sromal fibroblats that regulates breast cancer stem cells, Cancer Res, 72, 2768, 10.1158/0008-5472.CAN-11-3567 Parmiani, 2007, Universal and stemness-related tumor antigens: potential use in cancer immunotherapy, Clin Cancer Res, 13, 5675, 10.1158/1078-0432.CCR-07-0879 Engelmann, 2008, MCF7side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1, Cancer Res, 68, 2419, 10.1158/0008-5472.CAN-07-2249 Hirohashi, 2012, Cytotoxic T lymphocytes. Sniping cancer stem cells, Oncoimmunology, 1, 123, 10.4161/onci.1.1.18075 Segal, 2008, Epitope landscape in breast and colorectal cancer, Cancer Res, 68, 889, 10.1158/0008-5472.CAN-07-3095 Pleasance ED, Cheetham RK, Stephens PI, et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature. doi: o8658/doi10.1038. Gedye, 2009, Cancer/testis antigens can be immunological targets in clonogenic CD133 melanoma cells, Cancer Immunol Immunother, 58, 1635, 10.1007/s00262-009-0672-0 Koshio, 2013, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is an immunogenic target of cancer stem cells, Cancer Immunol Immunother, 62, 1619, 10.1007/s00262-013-1467-x Boiko, 2010, Human-melanoma initiating cells express neural crest nerve growth factor receptor CD271, Nature, 466, 10.1038/nature09161 Brown, 2012, Stem-like tumor-initiating cells isolated from IL13Ralpha2 expressing gliomas are targeted and killed by IL-13-zetakine-redirected T cells, Clin Cancer Res, 18, 2199, 10.1158/1078-0432.CCR-11-1669 Schmitz, 2007, Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy, Br J Cancer, 96, 1293, 10.1038/sj.bjc.6603696 Hua, 2011, The CD133+ tumor stem-like cells-associated antigens may elicit highly intense immune response against human malignant glioma, J Neurooncol, 105, 149, 10.1007/s11060-011-0572-y Inoda, 2011, Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells, Am J Pathol, 178, 1805, 10.1016/j.ajpath.2011.01.004 Mitra, 2012, EpCAM is a putative stem marker in retinoblastoma and an effective target for T-cell mediated immunotherapy, Mol Vis, 18, 290 Forshew, 2012, Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA, Sci Transl Med, 4, 136ra68, 10.1126/scitranslmed.3003726 Morgan, 2012, Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma, Hum Gene Ther, 23, 1043, 10.1089/hum.2012.041 Avril, 2012, Human glioblastoma stem-like cells are more sensitive to allogeneic NK and T cell-mediated killing compared with serum-cultured glioblastoma cells, Brain Pathol, 22, 159, 10.1111/j.1750-3639.2011.00515.x Todaro, 2009, Efficient killing of human colon cancer stem cells by γσT lymphocytes, J Immunol, 182, 7287, 10.4049/jimmunol.0804288 Tallerico, 2013, Human NK cells selective targeting of colon cancer-initiating cells: a role for natural cytotoxicity receptors and MHC class I molecules, J Immunol, 190, 2381, 10.4049/jimmunol.1201542 Pietra, 2009, Natural killer cells kill human melanoma cells with characteristics of cancer stem cells, Int Immunol, 21, 793, 10.1093/intimm/dxp047 Lai, 2012, Human ovarian cancer stem cells can be efficiently killed by γσT lymphocytes, Cancer Immunol Immunother, 61, 979, 10.1007/s00262-011-1166-4 Ning, 2012, Cancer stem cell vaccination confers significant antitumor immunity, Cancer Res, 72, 1853, 10.1158/0008-5472.CAN-11-1400 Visus, 2011, Targeting ALDH (bright) human carcinoma-initiating cells with ALDH1A1-specific CD8+ T cells, Clin Cancer Res, 17, 6174, 10.1158/1078-0432.CCR-11-1111 Glennie, 2005, Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells, Blood, 105, 2821, 10.1182/blood-2004-09-3696 Beyth, 2005, Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness, Blood, 105, 2214, 10.1182/blood-2004-07-2921 Roth, 2010, GDF-15 contributes to proliferation and immune escape of malignant gliomas, Clin Cancer Res, 16, 3851, 10.1158/1078-0432.CCR-10-0705 Noh, 2012, Cancer vaccination drives nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotypes, Cancer Res, 72, 1717, 10.1158/0008-5472.CAN-11-3758 Reim, 2009, Immunoselection of breast and ovarian cancer cells with trastuzumab and natural killer cells: selective escape of CD44high/CD24low/HER2low breast cancer stem cells, Cancer Res, 69, 8058, 10.1158/0008-5472.CAN-09-0834 Tao, 2012, Expression levels of Fas/FasL mRNA in human brain glioma stem cells, Mol Med Rep, 5, 1202 Schmidt, 2012, Cancer stem cells in the crosshairs, Cancer Discov, 2, 384, 10.1158/2159-8290.CD-ND2012-019 Kepp, 2011, Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy, Cancer Metastasis Rev, 30, 61, 10.1007/s10555-011-9273-4