Micropillar arrays as potential drug screens: Inhibition of micropillar-mediated activation of the FAK–Src–paxillin signaling pathway by the CK2 inhibitor CX-4945
Tài liệu tham khảo
Curtis, 1997, Topographical control of cells, Biomaterials, 18, 1573, 10.1016/S0142-9612(97)00144-0
Bettinger, 2009, Engineering substrate topography at the micro- and nanoscale to control cell function, Angew. Chem. Int. Ed., 48, 5406, 10.1002/anie.200805179
Stevens, 2005, Exploring and engineering the cell surface interface, Science, 310, 1135, 10.1126/science.1106587
MacQueen, 2013, Mesenchymal stem cell mechanobiology and emerging experimental platforms, J. R. Soc. Interface, 10, 20130179, 10.1098/rsif.2013.0179
Badique, 2013, Biomaterials, 34, 2991, 10.1016/j.biomaterials.2013.01.018
Nematollahi, 2009, Hexagonal micron scale pillars influence epithelial cell adhesion, morphology, proliferation, migration, and cytoskeletal arrangement, J. Biomed. Mater. Res., 91A, 149, 10.1002/jbm.a.32202
Bucaro, 2012, Fine-tuning the degree of stem cell polarization and alignment on ordered arrays of high-aspect-ratio nanopillars, ACS Nano, 6, 6222, 10.1021/nn301654e
Zhang, 2013, Effects of a hybrid micro/nanorod topography-modified titanium implant on adhesion and osteogenic differentiation in rat bone marrow mesenchymal stem cells, Int. J. Nanomed., 8, 257
Su, 2006, The geometric pattern of a pillared substrate influences the cell-process distribution and shapes of fibroblasts, Micron, 37, 699, 10.1016/j.micron.2006.03.007
Chevolleau, 2008, The motility of normal and cancer cells in response to the combined influence of substrate rigidity and anisotropic microstructure, Biomaterials, 29, 1541, 10.1016/j.biomaterials.2007.12.016
Frey, 2006, Cellular responses to substrate topography: role of myosin ii and focal adhesion kinase, Biophys. J., 90, 3774, 10.1529/biophysj.105.074526
Ankam, 2013, Substrate topography and size determine the fate of human embryonic stem cells to neuronal or glial lineage, Acta Biomater., 9, 4535, 10.1016/j.actbio.2012.08.018
Park, 2005, Chemically nanopatterned surfaces using polyelectrolytes and ultraviolet-cured hard molds, Nano Lett., 5, 1347, 10.1021/nl050592p
Cho, 2014, Replication of flexible polymer membranes with geometry-controllable nano-apertures via a hierarchical mould-based dewetting, Nat. Commun., 5, 3137, 10.1038/ncomms4137
Liliensiek, 2010, Modulation of human vascular endothelial cell behaviors by nanotopographic cues, Biomaterials, 31, 5418, 10.1016/j.biomaterials.2010.03.045
Jeon, 2015, Combined effects of substrate topography and stiffness on endothelial cytokine and chemokine secretion, ACS Appl. Mater. Int., 7, 4525, 10.1021/acsami.5b00554
Downing, 2013, Biophysical regulation of epigenetic state and cell reprogramming, Nat. Mater., 12, 1154, 10.1038/nmat3777
Sattler, 2000, Role of the cytoskeletal protein paxillin in oncogenesis, Crit. Rev. Oncogenesis, 11, 14, 10.1615/CritRevOncog.v11.i1.30
Kim, 2009, Src kinases as therapeutic targets for cancer, Nat. Rev. Clin. Oncol., 6, 587, 10.1038/nrclinonc.2009.129
Sachdev, 2009, Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion, BMC Cancer, 9, 12, 10.1186/1471-2407-9-12
Avizienyte, 2005, Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition, Curr. Opin. Cell Biol., 17, 542, 10.1016/j.ceb.2005.08.007
Tumbarello, 2005, Regulation of paxillin family members during epithelial–mesenchymal transformation: a putative role for paxillin δ, J. Cell. Sci., 118, 4849, 10.1242/jcs.02615
Parsons, 2000, Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement, Oncogene, 19, 5606, 10.1038/sj.onc.1203877
Owen, 1999, Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2, Mol. Cell Biol., 19, 4806, 10.1128/MCB.19.7.4806
Schaller, 2001, Paxillin: a focal adhesion-associated adaptor protein, Oncogene, 20, 6459, 10.1038/sj.onc.1204786
Wang, 2001, Focal adhesi‘on kinase is involved in mechanosensing during fibroblast migration, Proc. Natl. Acad. Sci. U.S.A., 98, 11295, 10.1073/pnas.201201198
Sonoda, 2000, Anti-apoptotic Role of Focal Adhesion Kinase (FAK): Induction of inhibitor-of-apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60, J. Biol. Chem., 275, 16309, 10.1074/jbc.275.21.16309
Mitra, 2006, Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors, Oncogene, 25, 5969, 10.1038/sj.onc.1209588
Kong, 2011, Down-regulation of phospho-non-receptor Src tyrosine kinases contributes to growth inhibition of cervical cancer cells, Med. Oncol., 28, 1495, 10.1007/s12032-010-9583-3
Li, 2009, Fibronectin promotes tyrosine phosphorylation of paxillin and cell invasiveness in the gastric cancer cell line AGS, Tumori, 95, 769, 10.1177/030089160909500621
Kalluri, 2009, The basics of epithelial–mesenchymal transition, J. Clin. Invest., 119, 1420, 10.1172/JCI39104
Cicchini, 2008, TGF β-induced EMT requires focal adhesion kinase (FAK) signaling, Exp. Cell Res., 314, 143, 10.1016/j.yexcr.2007.09.005
Lim, 2007, The regulation of integrin-mediated osteoblast focal adhesion and focal adhesion kinase expression by nanoscale topography, Biomaterials, 28, 1787, 10.1016/j.biomaterials.2006.12.020
Hamilton, 2007, The effect of substratum topography on osteoblast adhesion mediated signal transduction and phosphorylation, Biomaterials, 28, 1806, 10.1016/j.biomaterials.2006.11.041
Ghrebi, 2013, The effect of surface topography on cell shape and early ERK1/2 signaling in macrophages; linkage with FAK and Src, J. Biomed. Mater. Res. A, 101A, 2118, 10.1002/jbm.a.34509
Pierre, 2011, Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer, J. Med. Chem., 54, 635, 10.1021/jm101251q
Kim, 2012, Druggability of the CK2 inhibitor CX-4945 as an anticancer drug and beyond, Arch. Pharm. Res., 35, 1293, 10.1007/s12272-012-0800-9
Kim, 2013, CK2 inhibitor CX-4945 blocks TGF-β 1-induced epithelial-to-mesenchymal transition in A549 human lung adenocarcinoma cells, PLoS One, 8, e74342, 10.1371/journal.pone.0074342
Voulgari, 2009, Epithelial–mesenchymal transition in cancer metastasis: Mechanisms, markers and strategies to overcome drug resistance in the clinic, BBA Rev. Cancer, 1796, 75
Wang, 2001, Uniaxial cyclic stretch induces focal adhesion kinase (FAK) tyrosine phosphorylation followed by mitogen-activated protein kinase (MAPK) activation, Biochem. Biophys. Res. Commun., 288, 356, 10.1006/bbrc.2001.5775
Goffin, 2006, Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers, J. Cell Biol., 172, 259, 10.1083/jcb.200506179
Hamilton, 2005, “Gap guidance” of fibroblasts and epithelial cells by discontinuous edged surfaces, Exp. Cell Res., 309, 429, 10.1016/j.yexcr.2005.06.015