Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements
Robert Thänert1,2, JooHee Choi1, Kimberly A. Reske3, Tiffany Hink3, Anna Thänert1, Meghan A. Wallace3, Bin Wang1,2, Sondra Seiler3, Candice Cass3, Margaret H. Bost3, Emily L. Struttmann3, Zainab Hassan Iqbal3, Steven R. Sax3, Victoria J. Fraser3, Arthur W. Baker4,5, Katherine R. Foy4,5, Brett Williams6, Ben Xu6, Pam Capocci-Tolomeo7,8, Ebbing Lautenbach7,8,9
1The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO, USA
2Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA
3Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA
4Division of Infectious Diseases, Duke University School of Medicine, Durham, NC, USA
5Duke Center for Antimicrobial Stewardship and Infection Prevention, Durham, NC, USA
6Division of Infectious Diseases, Department of Internal Medicine, Rush Medical College, Chicago, IL, USA
7Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
8Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
9Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
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Cell Host & Microbe
Tập 30
1034-1047.e6
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