Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

Molecular Cell - Tập 49 Số 2 - Trang 359-367 - 2013
Gregory Hannum1, Justin Guinney2, Ling Zhao3,4,5, Li Zhang3,6,4,5, Guy Hughes3,4, SriniVas R. Sadda7, Brandy Klotzle8, Marina Bibikova8, Jian-Bing Fan8, Yuan Gao9, Rob Deconde1,10, Menzies Chen1, Indika Rajapakse11, Stephen Friend2, Trey Ideker1,10,4, Kang Zhang3,4,5
1Department of Bioengineering, University of California, San Diego, San Diego, CA 92093, USA
2Sage Bionetworks, Seattle, WA 98109, USA
3Department of Ophthalmology, University of California, San Diego, San Diego, CA 92093, USA
4Institute for Genomic Medicine, University of California, San Diego, San Diego, CA 92093, USA
5Molecular Medicine Research Center and Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China
6Guangzhou iGenomics, Guangzhou 510300, China
7Doheny Eye Institute, University of Southern California, Los Angeles, CA, 90033, USA
8Illumina, San Diego, CA 92122, USA
9Lieber Institute, Johns Hopkins University, Baltimore, MD 21205, USA
10Department of Medicine, University of California, San Diego, San Diego, CA 92093, USA
11Division of Basic Sciences and Biostatistics, Fred Hutchinson Cancer Research Center, Seattle, WA 98110, USA

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