IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways
Tóm tắt
Từ khóa
Tài liệu tham khảo
Miossec P: Interleukin-17 in rheumatoid arthritis. Arthritis Rheum. 2003, 48: 594-601. 10.1002/art.10816.
Cai L, Yin J, Starovasnik M, Hogue D, Hillan K, Mort J, Filvarorff E: Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo. Cytokine. 2001, 16: 10-21. 10.1006/cyto.2001.0939.
Bush K, Walker J, Lee C, Kirham B: Cytokine expression and synovial pathology in the initiation and spontaneous resolution phases of adjuvant arthritis: Interleukin-17 expression is upregulated in early disease. Clin Exp Immunol. 2001, 123: 487-495. 10.1046/j.1365-2249.2001.01469.x.
Kehlen A, Thiele K, Riemann D, Langer J: Expression, modulation and signaling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis. Clin Exp Immunol. 2002, 127: 539-546. 10.1046/j.1365-2249.2002.01782.x.
Katz Y, Nadiv O, Beer Y: Interleukin-17 enhances tumor necrosis factor α induced synthesis of interleukins 1, 6, and 8 in skin and synovial fibroblasts. Arthritis Rheum. 2001, 44: 2176-2184. 10.1002/1529-0131(200109)44:9<2176::AID-ART371>3.0.CO;2-4.
Alonzi T, Fattori E, Lazzaro D, Costa P, Probert L, Kollias G, De Benedetti F, Poli V, Ciliberto G: Interleukin 6 is required for the development of collagen-induced arthritis. J Exp Med. 1998, 187: 461-468. 10.1084/jem.187.4.461.
Joosten L, Lubberts E, Helsen M, Saxne T, Cornen-de Roo C, Heinegard D, van den Berg WB: Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis. Arthritis Res. 1999, 1: 81-91. 10.1186/ar14.
Lubberts E, Joosten L, Oppers B, van den Bersselaar L, Coenen-de Roo C, Kolls J, Schwarzenberger P, van de Loo F, van den Berg W: IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis. J Immunol. 2001, 167: 1004-1013.
Chabaud M, Lubberts E, Joosten L, van den Berg W, Miossec P: IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis. Arthritis Res. 2001, 3: 168-177. 10.1186/ar294.
Subramaniam S, Cooper R, Adunyah S: Evidence for the involvement of JAK/STAT pathway in the signaling mechanism of interleukin-17. Biochem Biophys Res Commun. 1999, 262: 14-19. 10.1006/bbrc.1999.1156.
Schwandner R, Yamaguchi K, Cao Z: Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction. J Exp Med. 2000, 191: 1233-1239. 10.1084/jem.191.7.1233.
Handel M, McMorrow L, Gravallese E: Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65. Arthritis Rheum. 1995, 38: 1762-1770.
Marok R, Winyard P, Coumbe A, Kus M, Blades S, Mapp P, Morris C, Blake D, Kaltschmidt C, Baeuerle P: Activation of the transcription factor nuclear factor-kappa B in human inflamed synovial tissue. Arthritis Rheum. 1996, 39: 583-591.
Georganas C, Liu H, Perlman H, Hoffmana A, Thimmapaya B, Pope R: Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-κB but not C/EBPβ or c-Jun. J Immunol. 2000, 165: 7199-7206.
Ziolkowska M, Koe A, Luszczykiewicz G, Ksiezopolska-Pietrzak K, Klimczak E, Chwalinska-Sadowska H, Maslinski W: High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporine A-sensitive mechanism. J Immunol. 2000, 164: 2832-2838.
Chabaud M, Durand J, Buchs N, Fossiez F, Page G, Frappart L, Miossec P: Human interleukin 17; a T cell-derived proinflammatory cytokine produced by the rheumatoid arthritis synovium. Arthritis Rheum. 1999, 42: 963-970. 10.1002/1529-0131(199905)42:5<963::AID-ANR15>3.0.CO;2-E.
Cho ML, Yoon CH, Hwang SY, Park MK, Min SY, Lee SH, Park SH, Kim HY: Effector function of type II collagen-stimulated T cells from rheumatoid arthritis patients. Arthritis Rheum.
Scuderi E, Convertino R, Molino N, Provenzano C, Marino M, Zoli A, Bartoccioni E: Effect of pro-inflammatory/anti-inflammatory agents on cytokine secretion by peripheral blood mononuclear cells in rheumatoid arthritis and systemic lupus erythematosus. Autoimmunity. 2003, 36: 71-77. 10.1080/0891693031000079275.
Woltman A, de Haji S, Boonstra J, Gobin S, Daha M, vab Kooten C: Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells. J Am Soc Nephrol. 2000, 11: 2044-2055.
Hata K, Andoh A, Shimada M, Fujino S, Bamba S, Araki Y, Okuno T, Fujiyama Y, Bamba T: IL-17 stimulates inflammatory responses via NF-κB and MAP kinase pathway in human colonic myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2002, 282: G1035-G1044.
Kim G, Jun J, Elkon K: Necessary role of phosphatidylinositol 3-kinase in transforming growth factor β-mediated activation of Akt in normal and rheumatoid arthritis synovial fibroblasts. Arthritis Rheum. 2002, 46: 1504-1511. 10.1002/art.10314.
Aidinis V, Plows D, Haralambous S, Armaka M, Papadopoulos P, Kanaki M, Koczan D, Thiesen J, Kollias G: Functional analysis of an arthritogenic synovial fibroblast. Arthritis Res Ther. 2003, 5: R140-R157. 10.1186/ar749.
Yamamura Y, Gupta R, Morita Y, He X, Pai R, Endres J, Freiberg A, Chung K, Fox D: Effector function of resting T cells: activation of synovial fibroblasts. J Immunol. 2001, 166: 2270-2275.
Chabaud M, Fossiez F, Taupin J-L, Miossec P: Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J Immunol. 1998, 161: 409-414.
Aggarwal S, Gurney A: IL-17: prototype member of an emerging cytokine family. J Leukoc Biol. 2002, 71: 1-8.
Shi Y, Ullrich S, Zhang J, Connolly K, Grzegorzewski K, Barber M, Wang W, Wathen K, Hodge V, Fisher C, Olsen H, Ruben S, Knyazev I, Cho Y-H, Kao V, Wilkinson K, Carrell J, Ebner R: A novel cytokine receptor-ligand pair. J Biol Chem. 2000, 275: 19167-19176. 10.1074/jbc.M910228199.
Lee J, Ho W-H, Maruoka M, Corpuz R, Baldwin D, Foster J, Goddard A, Yansura D, Vandlen R, Wood W, Gurney A: IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1. J Biol Chem. 2001, 276: 1660-1664. 10.1074/jbc.M008289200.
Kehlen A, Pachnio A, Thiele K, Langner J: Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6. Arthritis Res Ther. 2003, 5: R186-R192. 10.1186/ar762.
Shimada M, Andoh A, Hata K, Tasaki K, Araki Y, Fusiyama Y, Bamba T: IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators. J Immunol. 2002, 168: 861-868.
Hsu YM, Lucci J, Su L, Ehrenfels B, Garber E, Thomas D: Heteromultimeric complexes of CD40 ligand are present on the cell surface of human T lymphocytes. J Biol Chem. 1997, 272: 911-915. 10.1074/jbc.272.2.911.
Pietravalle F, Lecoanet-Henchoz S, Blasey H, Aubry JP, Elson G, Edgerton MD, Bonnefoy JY, Gauchat JF: Human native soluble CD40L is a biologically active trimer, processed inside microsomes. J Biol Chem. 1996, 271: 5965-5967. 10.1074/jbc.271.11.5965.
Morel J, Park C, Woods J, Koch A: A novel role for interleukin-18 in adhesion molecule induction through NFκB and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways. J Biol Chem. 2001, 276: 37069-37075. 10.1074/jbc.M103574200.