Bronchial artery infusion of mitomycin C in carcinoma of the lung
Tóm tắt
Fifteen patients with bronchial carcinoma were treated with infusions of 10 mg Mitomycin C (MMC) in the bronchial artery feeding the tumor. The treatment was repeated three times with 2–3 weeks interval between treatments. Half of the patients then received radiation to the tumor area and mediastinum. All tumors decreased in size, complete remission occurred in two and partial remission in five patients. Survival time, however, was not prolonged and esophageal complications occurred in several patients.
Tài liệu tham khảo
Brashear RE (1978) Should asymptomatic patients with inoperable bronchogenic carcinoma receive immediate radiotherapy? No. (editorial). Am Rev Respir Dis 117:411–414
Livingston RB (1977) Combination chemotherapy of broncogenic carcinoma. I. Non-oat cell. Cancer Treat Rev 4:153–165
Boijsen E, Dahlbäck O, Kugelberg J, Schüller H, Zsigmond M (1964) Die Behandlung des inoperablen Bronchuskarzinoms mit Zytostaticainfusion via AA. bronchiales. Thoraxchir Vask Chir 12:198–201
Kahn PC, Paul RE, Rheinlander HF (1965) Selective bronchial arteriography and intra-arterial chemotherapy in carcinoma of the lung. J Thorac Cardiovasc Surg 50:640–645
Haller JD, Bron KM, Wholey MH, Poller S, Enerson DM (1965) Selective bronchial artery catheterization for diagnostic and physiologic studies and chemotherapy for bronchogenic carcinoma. J Thoracic Cardiovasc Surg 51:143–152
Nordenström B (1966) Selective catheterization with Tifocyl injection of bronchomediastinal arteries in bronchial carcinoma. Acta Radiol Ther Phys Biol 4:298–304
Tate CF, Vamonte M, Agnew JR (1968) Bronchial arterial perfusion with cytotoxic agents for bronchogenic carcinoma. Am Rev Respir Dis 97:685–693
Neyazaki R, Ikeda M, Seki Y, Egawa N, Suzuki C (1969) Bronchial artery infusion therapy for lung cancer. Cancer 24:912–922
Ogata T, Yoneyama T (1975) Regional arterial infusion therapy for lung tumor (in Japanese). Gan To kagakuryoho (Cancer and Chemotherapy) p 921
Hellekant C (1979) Bronchial angiography and intra-arterial chemotherapy with mitomycin-C in bronchogenic carcinoma. Acta Radiol [Diagn] (Stockh) 20:478–494
Ekholm S, Albrechtsson U, Hellekant C, Jonsson K, Nyman U, Tylén U (1980) Cytostatic infusion into bronchial arteries in bronchogenic carcinoma. Ann Radiol (Paris) 4:346–348
Wakaki S, Marumo H, Tamioka K, Shimizu G, Kato E, Kamada H, Kudo S, Fujimoto (1958) Isolation of new fractions of antitumor Mitomycins. Antibiot Chemother 8:228–240
Lown JW (1979) The molecular mechanism of antitumor action of the Mitomycins. In: Carter, SK, Crooke ST (eds) Mitomycin C—current status and new developments. Academic Press, New York San Francisco London, pp 5–26
Lown JW, Begleiter A, Johnson D, Morgan AR (1976) Studies related to antitumor antibiotics. V. Reactions of Mitomycin C with DNA examined by ethidium fluorescence assay. Can J Biochem 54:100–119
Connors TA, Mitchley BCV, Rosenoer VM, Ross WCJ (1970) The effect of glucose pretreatment on the carcinostatic and toxic activities of some alkylating agents. Biochem Pharmacol 13:395–400
Reich SD (1979) Clinical pharmacology of Mitomycin C. In: Carter SK, Crooke ST (eds) Mitomycin C—current status and new developments. Academic Press, New York San Francisco London, pp 243–250
Frank W, Osterberg AE (1960) Mitomycin C (NSC-26980). An evaluation of the Japanese reports. Cancer Chemother Rep 9:114–119
Union Internationale Contre le Cancer (UICC) International Union Against Cancer (1974) Committee on Tumor Nomenclature (TNM). Classification of malignant tumors, 2nd edn. Geneva, Switzerland
Klopp CT, Alford TC, Bateman J, Berry GN, Winship T (1950) Fractionated intra-arterial cancer chemotherapy with methyl bis amine hydrochloride; a preliminary report. Ann Surg 132:811–832
Milne ENC (1967) Circulation of primary and metastatic pulmonary neoplasms. A postmortem microarteriographic study. AJR 100:603–619
Botenga ASJ (1970) Selective bronchial and intercostal arteriography. Williams and Wilkins, Baltimore
Hellekant C, Jonsson K (1981) Double blood supply of bronchogenic carcinoma from multiple arteries. Acta Radiol [Diagn] (Stockh) 22:403–406
Feigelson HH, Ravin HA (1965) Transverse myelitis following selective bronchial arteriography. Radiology 85:663–665
Mark JBD, Hockman RP, Carrington CB (1965) Experimental bronchial arterial-infusion of mechlorethamine. J Thorac Cardiovasc Surg 50:9–15
Steckel RJ, Doppman JL, Rolley RT, Martos EJ (1967) Rupture of the aorta after mechlorethamine HCl infusion of a bronchial artery. JAMA 199:936–939
Remy J, Wallaert C, Voisin C, Gerney-Rieux Ch (1968) Angiographie sélective des artères bronchiques. Presse Méd 76:729–732
Kardjien V, Symeonov A, Chankov I (1974) Etiology, pathogenesis and presentation of spinal cord lesions in selective angiography of the bronchial and intercostal arteries. Radiology 112:81–83