Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit

Cell - Tập 70 - Trang 419-429 - 1992
Ian D. Hiles1, Masayuki Otsu1, Stefano Volinia1, Michael J. Fry1, Ivan Gout1, Ritu Dhand1, George Panayotou1, Fernanda Ruiz-Larrea2, Andrew Thompson1, Nicholas F. Totty1, J.Justin Hsuan1, Sara A. Courtneidge3, Peter J. Parker3, Michael D. Waterfield1,4
1Ludwig Institute for Cancer Research London W1P 8BT England
2Department of Biochemistry and Molecular Biology University College London, England
3Differentiation Programme European Molecular Biology Laboratory 6900 Heidelberg, Germany
4Imperial Cancer Research Fund, Lincoln's Inn Fields, London, England

Tài liệu tham khảo

Ashmun, 1989, Monoclonal antibodies to the human CSF-1 receptor (c-fms proto-oncogene product) detect epitopes on normal mononuclear phagocytes and on human myeloid leukemic blast cells, Blood, 73, 827, 10.1182/blood.V73.3.827.827 Auger, 1991, Novel polyphosphoinositides in cell growth and activation, Cancer Cells, 3, 263 Auger, 1989, Phosphatidylinositol 3-kinase and its novel product, phosphatidylinositol 3-phosphate, are present in Saccharomyces cerevisiae, J. Biol. Chem., 264, 20181, 10.1016/S0021-9258(19)47043-9 Berridge, 1989, Inositol phosphates and cell signaling, Nature, 341, 197, 10.1038/341197a0 Cantley, 1991, Oncogenes and signal transduction, Cell, 64, 281, 10.1016/0092-8674(91)90639-G Carpenter, 1990, Purification and characterization of phosphatidylinositol 3-kinase from rat liver, J. Biol. Chem., 265, 19704, 10.1016/S0021-9258(17)45429-9 Chirgwin, 1979, Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease, Biochemistry, 18, 294, 10.1021/bi00591a005 Coughlin, 1989, Role of phosphatidylinositol kinase in PDGF receptor signal transduction, Science, 243, 1191, 10.1126/science.2466336 Courtneidge, 1987, An 81 kd protein complexed with middle T antigen and pp60c-src: a possible phosphatidylinositol kinase, Cell, 50, 1031, 10.1016/0092-8674(87)90169-3 Devereux, 1984, A comprehensive set of sequence analysis programs for the VAX, Nucl. Acids Res., 12, 387, 10.1093/nar/12.1Part1.387 Downes, 1991, Phosphoinositide 3-kinase: a new effector in signal transduction?, Cellular Signalling, 3, 501, 10.1016/0898-6568(91)90027-R Downes, 1990, myo -Inositol metabolites as cellular signals, Eur. J. Biochem., 193, 1, 10.1111/j.1432-1033.1990.tb19297.x Endemann, 1987, Bovine brain contains two types of phosphatidylinositol kinase, Biochemistry, 26, 6845, 10.1021/bi00395a039 Escobedo, 1988, A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF, Nature, 335, 85, 10.1038/335085a0 Escobedo, 1991, A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine, Mol. Cell. Biol., 11, 1125, 10.1128/MCB.11.2.1125 Escobedo, 1991, cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor, Cell, 65, 75, 10.1016/0092-8674(91)90409-R Frohman, 1988, Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer, 85, 8998 Hanks, 1988, The protein kinase family: conserved feature and deduced phylogeny of the catalytic domains, Science, 241, 42, 10.1126/science.3291115 Harvey, 1991, Random-primed cDNA synthesis facilitates the isolation of multiple 5′-cDNA ends by RACE, Nucl. Acids Res., 19, 4002, 10.1093/nar/19.14.4002 Henikoff, 1984, Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing, Gene, 28, 351, 10.1016/0378-1119(84)90153-7 Herman, 1990, Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae, Mol. Cell. Biol., 10, 6742, 10.1128/MCB.10.12.6742 Hu, 1992, Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors, Mol. Cell. Biol., 12, 981, 10.1128/MCB.12.3.981 Kaplan, 1986, Phosphatidylinositol metabolism and polyoma-mediated transformation, 83, 3624 Kaplan, 1987, Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity, Cell, 50, 1021, 10.1016/0092-8674(87)90168-1 Kaufman, 1989, The phosphorylation state of eukaryotic initiation factor 2 alters translational efficiency of specific mRNAs, Mol. Cell. Biol., 9, 946, 10.1128/MCB.9.3.946 Kazlauskas, 1989, Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins, Cell, 58, 1121, 10.1016/0092-8674(89)90510-2 Kazlauskas, 1990, Phosphorylation of the PDGF receptor β subunit creates a tight binding site for phosphatidylinositol 3 kinase, EMBO J., 9, 3279, 10.1002/j.1460-2075.1990.tb07527.x Kazlauskas, 1991, Functions of the major tyrosine phosphorylation site of the PDGF receptor β subunit, Cell Regulation, 2, 413, 10.1091/mbc.2.6.413 Kelly, 1992, Phosphatidylinositol-3-kinase in isolated rat adipocytes, J. Biol. Chem., 267, 3423, 10.1016/S0021-9258(19)50748-7 Knighton, 1991, Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase, Science, 253, 407, 10.1126/science.1862342 Knighton, 1991, Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase, Science, 253, 414, 10.1126/science.1862343 Koch, 1991, SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins, Science, 252, 668, 10.1126/science.1708916 Kozak, 1987, An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs, Nucl. Acids Res., 15, 8125, 10.1093/nar/15.20.8125 Kucera, 1990, Human platelets form 3-phosphorylated phosphoinositides in response to α-thrombin, U46-619, or GTPγS, J. Biol. Chem., 265, 5345, 10.1016/S0021-9258(19)39361-5 Kypta, 1990, Association between the PDGF receptor and members of the src family of tyrosine kinases, Cell, 62, 481, 10.1016/0092-8674(90)90013-5 Lips, 1989, Phosphatidylinositol 3-phosphate is present in normal and transformed fibroblasts and is resistant to hydrolysis by bovine brain phospholipase C II, J. Biol. Chem., 264, 8759, 10.1016/S0021-9258(18)81858-0 Majerus, 1990, Recent insights in phosphatidylinositol signaling, Cell, 63, 459, 10.1016/0092-8674(90)90442-H Maniatis, 1982 McGlade, 1992, SH2 domains of the p85α subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors, Mol. Cell. Biol., 12, 991, 10.1128/MCB.12.3.991 Morgan, 1990, Purification and characterization of bovine brain type I phosphatidylinositol kinase, Eur. J. Biochem., 191, 761, 10.1111/j.1432-1033.1990.tb19185.x Otsu, 1991, Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase, Cell, 65, 91, 10.1016/0092-8674(91)90411-Q Page, 1989, p36C: an improved baculovirus expression vector for producing high levels of mature recombinant proteins, Nucl. Acids Res., 17, 454, 10.1093/nar/17.1.454 Rhee, 1991, Inositol phospholipid-specific phospholipase C: interaction of the γ1 isoform with tyrosine kinase, Trends Biochem. Sci., 16, 297, 10.1016/0968-0004(91)90122-C Rigby, 1977, Labelling oligonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I, J. Mol. Biol., 113, 237, 10.1016/0022-2836(77)90052-3 Robinson, 1988, Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases, Mol. Cell. Biol., 8, 4936, 10.1128/MCB.8.11.4936 Saraste, 1990, The P-loop: a common motif in ATP- and GTP-binding proteins, Trends Biochem. Sci., 15, 430, 10.1016/0968-0004(90)90281-F Serunian, 1989, Polyphosphoinositides produced by the phosphatidylinositol 3-kinase are poor substrates for phospholipase C from rat liver and bovine brain, J. Biol. Chem., 264, 17809, 10.1016/S0021-9258(19)84645-8 Shibasaki, 1991, Two types of phosphatidylinositol 3-kinase from bovine thymus, J. Biol. Chem., 266, 8108, 10.1016/S0021-9258(18)92948-0 Shurtleff, 1990, Structural features of the colonystimulating factor 1 receptor that affect its association with phosphatidylinositol 3-kinase, EMBO J., 9, 2415, 10.1002/j.1460-2075.1990.tb07417.x Skolnik, 1991, Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases, Cell, 65, 83, 10.1016/0092-8674(91)90410-Z Stephens, 1991, Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in neutrophils, Nature, 351, 33, 10.1038/351033a0 Summers, 1987, A manual of methods for baculovirus vectors and insect cell culture procedures, Texas Agri. Exp. Station Bull. No 155 Talmage, 1989, Phosphorylation of middle T by pp60c-src: a switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesis, Cell, 59, 55, 10.1016/0092-8674(89)90869-6 Totty, 1992, Accelerated high sensitivity microsequencing of proteins and peptides using a miniature reaction cartridge, Protein Science, 1, 10.1002/pro.5560010914 Traynor-Kaplan, 1988, An inositol tetrakisphosphate-containing phospholipid in activated neutrophils, Nature, 334, 353, 10.1038/334353a0 Ullrich, 1990, Signal transduction by receptors with tyrosine kinase activity, Cell, 61, 203, 10.1016/0092-8674(90)90801-K Ulug, 1990, Phosphatidylinositol metabolism in cells transformed by polyoma middle T antigen, J. Virol., 64, 3895, 10.1128/JVI.64.8.3895-3904.1990 Varticovski, 1989, The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol 3-kinase, Nature, 342, 699, 10.1038/342699a0 Whitley, 1987, SGHTL-34, a thyrotrophin-responsive immortalized human thyroid cell line generated by transfection, Mol. Cell. Endocrinol., 52, 279, 10.1016/0303-7207(87)90056-6 Whitman, 1985, Association of phosphatidylinositol kinase activity with polyoma middle-T component for transformation, Nature, 315, 239, 10.1038/315239a0 Whitman, 1987, Evidence for two distinct phosphatidylinositol kinases in fibroblasts, Biochem. J., 247, 165, 10.1042/bj2470165 Whitman, 1988, Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate, Nature, 332, 644, 10.1038/332644a0 Yanisch-Perron, 1985, Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors, Gene, 33, 103, 10.1016/0378-1119(85)90120-9